Results 161 to 170 of about 1,433,465 (359)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Machine learning models for the prediction of hydrogen solubility in aqueous systems. [PDF]

Sci Rep
Maleki M, Akbari A, Kazemzadeh Y, Ranjbar A.   +3 more
europepmc   +1 more source

Distribution of Total Soluble Solids, Ascorbic Acid, Total Acid, and Bromelin Activity in The Fruit of the Natal Pineapple (Ananas Comosus L. MERR.)

, 1953
Erston V. Miller, Gladys Downey Hall
openalex   +2 more sources

CXXVII.—Isolation and synthesis of p-hydroxyphenylethylamine, an active principle of ergot soluble in water [PDF]

, 1909
George Barger
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Data-driven frameworks to robustly predict solubility parameter of diverse polymers. [PDF]

Sci Rep
Hassan R, Kazemi MR.
europepmc   +1 more source

Solubility Products and Solubility Concepts

, 2017
Tadeusz Michałowski, Anna Maria Michałowska-Kaczmarczyk, Aneta Spórna-Kucab   +2 more
openaire   +3 more sources

XXXIV.—Solubilities of the calcium salts of the acids of the acetic series [PDF]

, 1902
John S. Lumsden
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Data-driven organic solubility prediction at the limit of aleatoric uncertainty. [PDF]

Nat Commun
Attia L, Burns JW, Doyle PS, Green WH.
europepmc   +1 more source