CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
CO<sub>2</sub> Solubility in Aqueous Solutions of Amine-Ionic Liquid Blends: Experimental Data for Mixtures with AMP and MAPA and Modeling with the Modified Kent-Eisenberg Model. [PDF]
Kontos G, Tsivintzelis I.
europepmc +1 more source
The Acid-soluble Nucleotides of Barley and Oat Plants. [PDF]
Rolf Bergkvist +6 more
openalex +1 more source
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Terpene-Derived Low-Viscosity Deep Eutectic Solvent for Energy-Efficient CO<sub>2</sub> Absorption. [PDF]
Hait S, Mahanta U.
europepmc +1 more source
Structure and composition of soluble feather keratin [PDF]
A. M. Woodin
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Solubility and Thermodynamics of Lithium Carbonate in Its Precipitation Mother Liquors. [PDF]
Ge H, Wang H, Wang M.
europepmc +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
Light-Cured Dental Fillings Containing Quinoline and Quinoxaline Derivatives: The Influence of Sorption and Solubility on Color Change-Part III. [PDF]
Pyszka I +2 more
europepmc +1 more source

