Results 71 to 80 of about 1,117,205 (307)

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Flory-Huggins theory for the solubility of heterogeneously-modified polymers

open access: yes, 2007
Many water soluble polymers are chemically modified versions of insoluble base materials such as cellulose. A Flory-Huggins model is solved to determine the effects of heterogeneity in modification on the solubility of such polymers.
Warren, Patrick B.
core   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Chitosan Grafted With β-Cyclodextrin: Synthesis, Characterization, Antimicrobial Activity, and Role as Absorbefacient and Solubilizer

open access: yesFrontiers in Chemistry, 2019
We synthesized chitosan grafted with β-cyclodextrin (CD-g-CS) from mono-6-deoxy-6-(p-toluenesulfonyl)-β-cyclodextrin and chitosan. Two different amounts of immobilized β-cyclodextrin (β-CD) on CD-g-CS (QCD: 0.643 × 103 and 0.6 × 102 μmol/g) were ...
Wen-Ya Ding   +19 more
doaj   +1 more source

Path Integral Solubility of a General Two-Dimensional Model [PDF]

open access: yes, 1994
The solubility of a general two dimensional model, which reduces to various models in different limits, is studied within the path integral formalism.
A. Bassetto   +14 more
core   +2 more sources

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Physicochemical Characterization of Finasteride Nanosystem for Enhanced Topical Delivery

open access: yesInternational Journal of Nanomedicine, 2021
Malik Muhammad Irfan,1,2 Shefaat Ullah Shah,1,2 Ikram Ullah Khan,3 Muhammad Usman Munir,4 Nauman Rahim Khan,1,2 Kifayat Ullah Shah,1 Saif Ur Rehman,5 Muhammad Sohaib,1,2 Hafiz Muhammad Basit,1,2 Saima Mahmood1,2 1Department of Pharmaceutics, Faculty of ...
Irfan MM   +9 more
doaj  

The concentration of homocysteine-derived disulfides in human coronary artery [PDF]

open access: yes, 2007
*Background* Based on previous findings, we have estimated that, in injured coronary artery tissue, the low molecular weight disulfides homocystine and cysteine-homocysteine, otherwise identified as oxidized homocysteine equivalents (OHcyE ...
Gaetano De Tommaso   +3 more
core   +1 more source

Entropic Stabilization and Retrograde Solubility in Zn4Sb3

open access: yes, 2010
Zn4Sb3 is shown to be entropically stabilized versus decomposition to Zn and ZnSb though the effects of configurational disorder and phonon free energy. Single phase stability is predicted for a range of compositions and temperatures.
Pomrehn, Gregory S.   +3 more
core   +1 more source

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