Results 71 to 80 of about 2,048,035 (343)
Formation of Metastable Solid Solutions in Bi-Ge Films during Low-Temperature Treatment
MetalsWe investigated the mechanism and kinetics of the formation of metastable BiGe solid phases during the amorphous-to-crystalline transformation of Ge films in contact with Bi.
Sergiy Bogatyrenko +3 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
PharmaceuticalsObjectives: This study was performed to simultaneously improve the solubility, permeability, and pharmacological activity of decoquinate (DQ). Methods: A ternary DQ solid dispersion with hydroxypropyl-β-cyclodextrin (HP-β-CD) and tea saponin (TS) was ...
Wei Wei, Qihong Zhang, Weike Su
doaj +1 more source
SOLUBILITY AND DESTRUCTION OF OIL IN SEA WATER
Юг России: экология, развитие, 2014 The solubility and the destruction of crude oil in seawater in conditions of the Caspian sea have been studied.
A. S. Abdusamadov +6 more
doaj +1 more source
Solubility of lignin and acetylated lignin in organic solvents.
, 2017 The solubility of four lignin samples and their acetylated forms was determined in a series of organic solvents to investigate the relationship between solubility and the solubility parameter.
J. Sameni, S. Krigstin, M. Sain
semanticscholar +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Journal of Applied Pharmaceutical ResearchBackground: The present work aimed to develop spherical agglomerates of Atazanavir (ATZR) with enhanced flow properties, compressibility, solubility, and dissolution. 22 full factorial design approach was employed to develop agglomerates.
Ashok T Jadhav, Sanjay S. Pekamwar
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
, 2014 Pharmaceutical particle technology is employed to improve poor aqueous solubility of drug compounds that limits in vivo bioavailability owing to their low dissolution rate in the gastrointestinal fluids following oral administration.
Prakash Khadka +8 more
semanticscholar +1 more source