Results 81 to 90 of about 514,430 (322)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Transparent ultraviolet-shielding composite films made from dispersing pristine zinc oxide nanoparticles in low-density polyethylene

open access: yesNanotechnology Reviews, 2020
This work proposes an approach to fabricate flexible transparent ultraviolet (UV)-shielding membrane by casting method, which uniformly disperses pristine zinc oxide nanoparticles (NPs) in low-density polyethylene (LDPE). The critical conditions for film
Cui Lina   +4 more
doaj   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

THERMODYNAMIC STUDY OF THE SOLUBILITY OF SODIUM SULFADIAZINE IN SOME ETHANOL + WATER COSOLVENT MIXTURES

open access: yesVitae, 2010
Sodium sulfadiazine (SD-Na) is a drug extensively used for the treatment of certain infections caused by several kinds of microorganisms. Although SD-Na is widely used nowadays in therapeutics, the physicochemical information about their aqueous ...
Daniel R. DELGADO, Fleming MARTÍNEZ R.
doaj  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

On locally defined formations of soluble Lie and Leibniz algebras [PDF]

open access: yesarXiv, 2011
It is well-known that all saturated formations of finite soluble groups are locally defined and, except for the trivial formation, have many different local definitions. I show that for Lie and Leibniz algebras over a field of characteristic 0, the formations of all nilpotent algebras and of all soluble algebras are the only locally defined formations ...
arxiv  

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

On groups with all subgroups subnormal or soluble of bounded derived length [PDF]

open access: yesGlasgow Math. J. 56 no. 1 (2014), 221--227, 2012
In this paper, we deal with locally graded groups whose subgroups are either subnormal or soluble of bounded derived length, say d. In particular, we prove that every locally (soluble-by-finite) group with this property is either soluble or an extension of a soluble group of derived length at most d by a finite group, which fits between a minimal ...
arxiv  

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