Results 121 to 130 of about 1,040,538 (251)

Riparian and stream enhancement project evaluation

, 2002
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF title page (viewed on Oct. 19, 2006)"8-30-02."

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Mevacor/Poly(vinyl acetate/2-hydroxyethyl methacrylate) as Solid Solution: Preparation, Solubility Enhancement and Drug Delivery. [PDF]

Polymers (Basel), 2023
Alassaf M, Alqahtani SM, Al Khulaifi RS, Saeed WS, Alsubaie FS, Semlali A, Aouak T.   +6 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Enhancement of Rice Bran Protein Solubility via pH-Driven Modification

Shipin gongye ke-ji
To enhance the solubility of rice bran protein (RBP) and thereby improve its application performance in food processing, the pH-driven method was employed in this study, under which RBP was treated at pH conditions of 1.5, 2.5, 3.5, 10, 11, and 12, and ...
Fengzhu TIAN, Dan LI, Feng ZUO, Hao HU
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

A new model to correlate solubility of drug compounds in supercritical carbon dioxide

Chemical Thermodynamics and Thermal Analysis
A new solubility model based on enhancement factor concept is proposed to correlate solubility of drug compounds in supercritical carbon dioxide (SCCO2). The correlating ability of the new model is compared with existing solubility model.
Amrithaa Raghavan, Ratna Surya Alwi, Geetha Devi M, Chandrasekhar Garlapati   +3 more
doaj   +1 more source

Erratum: Development of a quaternary ammonium poly (amidoamine) dendrimer-based drug carrier for the solubility enhancement and sustained release of furosemide. [PDF]

Front Chem, 2023
Frontiers Production Office.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Eplerenone Crystal Nanosuspension for Solubility Enhancement: Preparation and Evaluation

Ma’aen Journal for Medical Sciences, 2023
Hawraa k. Khafeef, Nawal A. Rajab
doaj   +2 more sources

Solubility Enhancement of Antidiabetic Drugs Using a Co-Crystallization Approach. [PDF]

ChemistryOpen, 2021
Batisai E.
europepmc   +1 more source