Results 61 to 70 of about 176,621 (285)

PERSPECTIVE OF INNOVATION DRUG FORMULATION WITH DARUNAVIR ETHANOLAT

open access: yesРазработка и регистрация лекарственных средств, 2019
Article shows the results of development and technological issues of darunavir ethanolate in capsule form. Soluplus was used to increase the biopharmaceutical characteristics of current drug formulation.
S. A. Zolotov   +3 more
doaj  

Speciation and Mobilization of Toxic Heavy Metal Ions by Methanogenic Bacteria [PDF]

open access: yes, 1993
HWRIC Project HWR 92 ...
Conver, Shawn   +5 more
core  

Production of protein extracts from Swedish red, green, and brown seaweeds, Porphyra umbilicalis Kützing, Ulva lactuca Linnaeus, and Saccharina latissima (Linnaeus) J. V. Lamouroux using three different methods [PDF]

open access: yes, 2018
peer-reviewedThe demand for vegetable proteins increases globally and seaweeds are considered novel and promising protein sources. However, the tough polysaccharide-rich cell walls and the abundance of polyphenols reduce the extractability and ...
Carlsson, Nils-Gunnar   +5 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Hydrotropic Hydrogels Prepared from Polyglycerol Dendrimers: Enhanced Solubilization and Release of Paclitaxel

open access: yesGels, 2022
Polyglycerol dendrimers (PGD) exhibit unique properties such as drug delivery, drug solubilization, bioimaging, and diagnostics. In this study, PGD hydrogels were prepared and evaluated as devices for controlled drug release with good solubilization ...
Tooru Ooya, Jaehwi Lee
doaj   +1 more source

The Carboxyl-Terminal Segment of Apolipoprotein A-V Undergoes a Lipid-Induced Conformational Change [PDF]

open access: yes, 2010
Apolipoprotein (apo) A-V is a 343-residue, multidomain protein that plays an important role in regulation of plasma triglyceride homeostasis. Primary sequence analysis revealed a unique tetraproline sequence (Pro293-Pro296) near the carboxyl terminus of ...
Lee, B. L.   +4 more
core   +2 more sources

Obtaining a bioadsorbent from orange peel suitable for batch and continous treatment [PDF]

open access: yes, 2020
One form of chemical contamination involves the contribution of heavy metals to the ecosystem mainly from industrial spills and mining operations. The most toxic heavy metals are cadmium, copper, chromium, mercury, nickel, lead and zinc.
García Raurich, Josep   +2 more
core   +3 more sources

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Phosphate Solubilizing Microorganism Bacillus sp. MVY-004 and Its Significance for Biomineral Fertilizers’ Development in Agrobiotechnology

open access: yesBiology, 2022
In this study, a phosphate solubilizing microorganism was isolated from the soil of an agricultural field in Lithuania. Based on 16S rRNA gene sequence analysis, the strain was identified as Bacillus sp.
Raimonda Mažylytė   +5 more
doaj   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

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