Results 141 to 150 of about 7,307 (207)

Structure-Based Design of PROTACS for the Degradation of Soluble Epoxide Hydrolase. [PDF]

J Med Chem
Schönfeld J, Brunst S, Ciomirtan L, Willmer L, Chromik MA, Kumar A, Froemel T, Liebisch N, Hackspacher A, Ehrler JHM, Wintermeier L, Hesse C, Fiedler J, Heering J, Freitag H, Zardo P, Fieguth HG, Brüggerhoff A, Jakob J, Häupl B, Weizel L, Kaiser A, Schubert-Zsilavecz M, Oellerich T, Fleming I, Schebb NH, Fürst R, Kannt A, Knapp S, Proschak E, Hiesinger K.   +30 more
europepmc   +1 more source

Structural modification of 5-alkyl-4-phenyl-thiazole-based fatty acid amide hydrolase and soluble epoxide hydrolase inhibitors to alleviate orofacial inflammatory pain in the rat. [PDF]

BBA Adv
Gorostiza G, Mercado M, Pavana L, Carr D, Yuan C, Tsang A, Gomez K, Minton I, Carrillo D, Berumen M, Pecic S, Kandasamy R.   +11 more
europepmc   +1 more source

Transplantation of Soluble Epoxide Hydrolase Inhibitor-Treated Human Brown Adipocytes Promotes Adipose Tissue Activation in High-Fat-Diet-Fed Nude Mice. [PDF]

Int J Mol Sci
Wu H, Xu X, Chen J, Morisseau C, Hammock BD, Tseng YH, Zhao L.   +6 more
europepmc   +1 more source

Inhibition of Soluble Epoxide Hydrolase Prevents Docetaxel-Induced Painful Peripheral Neuropathy. [PDF]

Int J Mol Sci
Wagner KM, Yang J, Morisseau C, Hammock BD.   +3 more
europepmc   +1 more source

Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy. [PDF]

JACC Basic Transl Sci
Panigrahy D, Kelly AG, Quinlivan KM, Wang W, Yang J, Hwang SH, Gillespie M, Howard IV, Bueno-Beti C, Asimaki A, Penna V, Lavine K, Edin ML, Zeldin DC, Hammock BD, Saffitz JE.   +15 more
europepmc   +1 more source

Dual therapy with vildagliptin and sacubitril/valsartan alleviates portal hypertension and inhibits soluble epoxide hydrolase in cirrhotic rats. [PDF]

World J Gastroenterol
Oyama M, Kaji K, Nishimura N, Hanatani J, Nakatani T, Nishimura N, Shibamoto A, Asada S, Tsuji Y, Kitagawa K, Sato S, Namisaki T, Yoshiji H.   +12 more
europepmc   +1 more source

Allosteric Ensembles Elucidate Mechanisms of Inhibition in Human Soluble Epoxide Hydrolase

Conte M, Qiu Q, Carmona OG, Abis G, Fraternali F.   +4 more
europepmc   +1 more source

Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: <i>in vivo</i> efficacy in a murine model of chemotherapy-induced neuropathic pain. [PDF]

J Enzyme Inhib Med Chem
Codony S, Jora B, Santos-Caballero M, Qiu Q, Calvó-Tusell C, Escriche C, Turcu AL, Prischi F, Bartra C, Val C, Morisseau C, Pérez B, Bertran-Mostazo A, Osuna S, Corpas R, Griñán-Ferré C, Galdeano C, Loza MI, Pallàs M, Sanfeliu C, Hammock BD, Brea J, Feixas F, Conte MR, Cobos EJ, Vázquez S.   +25 more
europepmc   +1 more source

Intradomain Allosteric Regulation of Soluble Epoxide Hydrolase by Its Substrates. [PDF]

Int J Mol Sci
Matsumura S, Shida A, Tsuchii M, Wada M, Charneau J, Tsuji M, Hasumi K, Suzuki E.   +7 more
europepmc   +1 more source

Endothelial soluble epoxide hydrolase links polyunsaturated fatty acid metabolism to oxidative stress and atherosclerosis progression. [PDF]

Redox Biol
Cao M, Li M, Li X, Li Y, Chen Y, Drekolia MK, Cheng X, Lagos FD, Bibli SI, Hu J.   +9 more
europepmc   +1 more source