Results 161 to 170 of about 7,307 (207)

Inhibitors of soluble epoxide hydrolase and cGAS/STING repair defects in amyloid-β clearance underlying vascular complications of Alzheimer's disease. [PDF]

J Alzheimers Dis
Fiala M, Hammock BD, Hwang SH, Whitelegge J, Paul K, Kaczor-Urbanowicz KE, Urbanowicz A, Kesari S.   +7 more
europepmc   +1 more source

Soluble epoxide hydrolase: a next-generation drug target for Alzheimer's disease and related dementias. [PDF]

Neural Regen Res
Gregory A, Tang C, Fan F.
europepmc   +1 more source

Microglial pro-inflammatory mechanisms induced by monomeric C-reactive protein are counteracted by soluble epoxide hydrolase inhibitors. [PDF]

Int Immunopharmacol
Bartra C, Vuraić K, Yuan Y, Codony S, Valdés-Quiroz H, Casal C, Slevin M, Máquez-Kisinousky L, Planas AM, Griñán-Ferré C, Pallàs M, Morisseau C, Hammock BD, Vázquez S, Suñol C, Sanfeliu C.   +15 more
europepmc   +1 more source

Inhibition of soluble epoxide hydrolase reverses bone loss in periodontitis by upregulating EMCN and inhibiting osteoclasts. [PDF]

Stem Cell Res Ther
Li J, Kou N, Shi X, Kong L, Chen W, Yang X, Zhao Y, Zhao J, Wang F.   +8 more
europepmc   +1 more source

Inhibitory Activity of Glycosides from Elsholtzia ciliata against Soluble Epoxide Hydrolase and Cytokines in RAW264.7 Cells. [PDF]

J Microbiol Biotechnol
Kim JH, Park JH, Han KS, Lee ES, Kim YG, Kim YI, Koo SC, Cho BO.   +7 more
europepmc   +1 more source

Preclinical Evaluation of Soluble Epoxide Hydrolase Inhibitor AMHDU against Neuropathic Pain. [PDF]

Int J Mol Sci
Babkov D, Eliseeva N, Adzhienko K, Bagmetova V, Danilov D, McReynolds CB, Morisseau C, Hammock BD, Burmistrov V.   +8 more
europepmc   +1 more source

Soluble epoxide hydrolase inhibition impairs triggering receptor expressed on myeloid cells-1 in periodontal tissue. [PDF]

J Periodontal Res
Vargas BDS, Vargas BSF, Clemente-Napimoga JT, Hammock BD, Abdalla HB, Van Dyke TE, Napimoga MH.   +6 more
europepmc   +1 more source

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Natural soluble epoxide hydrolase inhibitors from Alisma orientale and their potential mechanism with soluble epoxide hydrolase

International Journal of Biological Macromolecules, 2021
Inhibition of soluble epoxide hydrolase (sEH) is considered to be an effective treatment for inflammation-related diseases, and small molecules origin from natural products show promising activity against sEH. Two undescribed protostanes, 3β-hydroxy-25-anhydro-alisol F (1) and 3β-hydroxy-alisol G (2) were isolated from Alisma orientale and identified ...
Cheng-Peng Sun, Wen-Yu Zhao, Xiangge Tian   +2 more
exaly   +3 more sources