Results 121 to 130 of about 7,307 (207)

The involvement of soluble epoxide hydrolase in the development of cardiovascular diseases through epoxyeicosatrienoic acids

Frontiers in Pharmacology
Arachidonic acid (AA) has three main metabolic pathways: the cycloxygenases (COXs) pathway, the lipoxygenases (LOXs) pathway, and the cytochrome P450s (CYPs) pathway. AA produces epoxyeicosatrienoic acids (EETs) through the CYPs pathway.
Shan Jiang, Shan Jiang, Siyi Han, Dao Wen Wang, Dao Wen Wang   +4 more
doaj   +1 more source

Downregulation of osteoclast differentiation and activation by the soluble epoxide hydrolase inhibition. [PDF]

J Pharmacol Exp Ther
Martins G, Oliveira D, Rivas CA, Clemente-Napimoga JT, Hammock BD, Van Dyke TE, Napimoga MH, Abdalla HB.   +7 more
europepmc   +1 more source

Inhibition of soluble epoxide hydrolase ameliorates renal injury in IgA nephropathy by restoring epoxyeicosatrienoic acids. [PDF]

iScience
Yin HH, Fu X, Qiao Q, Yang E, Liu YN, Bai Y, Huang L, Chen YY, Huang ZY, Yu DC, Dai P, Pan QJ, Meng YW, Yin SY, Liu X, Nie S, Deng BQ, He Y, Liu JY.   +18 more
europepmc   +1 more source

Soluble Epoxide Hydrolase Inhibitors Improve Cornea Alkali Wound Healing. [PDF]

FASEB J
Lu X, Morisseau C, Jain K, Chen Z, Estes AJ, Zeldin D, Gruzdev A, Ahmed A, Cook H, Hammock BD, Watsky MA.   +10 more
europepmc   +1 more source

Novel Pyridone Carboxamide Derived Compounds as Soluble Epoxide Hydrolase Inhibitors for Treating Diabetic Retinopathy. [PDF]

ACS Med Chem Lett
Sabnis RW.
europepmc   +1 more source

Soluble epoxide hydrolase in the liver orchestrates abdominal aortic aneurysm formation in mice. [PDF]

Commun Biol
Kim DS, Horimatsu T, Ogbi M, Goo B, Shi H, Veerapaneni P, Chouhaita R, Cyriac N, Moses M, Prasad R, Cave S, Benson TW, Harb R, Aboud G, Sellers HG, Shivers M, Haigh S, Fulton DJ, Csányi G, Huo Y, Long X, Coffey P, Lee R, Guha A, Zhi W, Young L, Zeldin DC, Hwang SH, Hammock BD, Weintraub NL, Kim HW.   +30 more
europepmc   +1 more source

A novel inhibitor of soluble epoxide hydrolase that adducts C521 is cardioprotective. [PDF]

Redox Biol
Charles RL, Fernandez-Caggiano M, Rudyk O, Tyson-Hirst I, Ehteramyan M, Switzer CH, Buccafusca R, Rajeeve V, Bianchi K, Morales V, Finch AJ, Eaton P.   +11 more
europepmc   +1 more source

Limonin induces ferroptosis in cervical squamous cell carcinoma by activating the expression of soluble epoxide hydrolase 2 protein. [PDF]

PLoS One
Wu Q, Bai S, Wang P, Han L, Song L, Su L, Ren Y.   +6 more
europepmc   +1 more source

Inactivation of the Phosphatase Activity of Soluble Epoxide Hydrolase Modulates SIRT3 and Attenuates Experimental Pulmonary Hypertension. [PDF]

Compr Physiol
Leuillier M, Chelgham M, Messaoudi H, Tu L, Ménoret S, Thuillet R, Groussard D, Lillich FF, Ottaviani M, Nicol L, Mulder P, Humbert M, Richard V, Anegon I, Morisseau C, Proschak E, Guignabert C, Bellien J.   +17 more
europepmc   +1 more source

Soluble epoxide hydrolase inhibition preserves alveolar bone in experimental periodontitis with estrogen deficiency. [PDF]

Front Immunol
Ritter C, Silva Pacheco P, Mattos LBT, Soares MQS, Moreira DD, Rubira-Bullen IRF, Duarte MAH, Van Dessel J, Hammock BD, Carbone L, Clemente-Napimoga JT, Abdalla HB, Napimoga MH.   +12 more
europepmc   +1 more source