Results 121 to 130 of about 467,321 (167)

Chronic Hyperammonemia in Rats Impairs Activation of Soluble Guanylate Cyclase in Neurons and in Lymphocytes: A Putative Peripheral Marker for Neurological Alterations

, 2009
Chronic hyperammonemia impairs the glutamate-nitric oxide- cGMP pathway in rat brain in vivo. The aims of this work were to assess whether hyperammonemia impairs modulation of soluble guanylate cyclase, and to look for a peripheral marker for impairment ...
鄧哲明, Miñana, Marı́a-Dolores; Corbalán, Regina; Montoliu, Carmina; Teng, Che-Ming; Felipo, Vicente   +1 more
core  

The Distribution of Nitric Oxide-Synthesizing Neurons and Soluble Guanylate Cyclase in Relation to Dopaminergic Systems in the Pigeon Brain. [PDF]

J Comp Neurol
Steinemer A, Ziegler M, Haselhuhn K, Güntürkün O, Rook N.   +4 more
europepmc   +1 more source

Effects of a Soluble Guanylate Cyclase Stimulator Riociguat on Contractility of Isolated Pulmonary Artery and Hemodynamics of U46619-Induced Pulmonary Hypertension in Dogs. [PDF]

Vet Sci, 2023
Kameshima S, Nakamura Y, Uehara K, Kodama T, Yamawaki H, Nishi K, Okano S, Niijima R, Kimura Y, Itoh N.   +9 more
europepmc   +1 more source

Cardioprotective Effects of Soluble Guanylate Cyclase and Its α1 Subunit on Myocardial Ischemia/Reperfusion Injury via the PGC-1α/UCP2 Pathway. [PDF]

J Cardiovasc Pharmacol
Li J, Li X, Chen Y, Fang L, Li Q, Wu H, Liu Y, Qi X, Wei L, Wei L.   +9 more
europepmc   +1 more source

Neuroprotective Effect of a Novel Soluble Guanylate Cyclase Activator Runcaciguat in Diabetic and Ischemic Retinopathy. [PDF]

Diabetes
Duh EJ, Xu Z, Cho H, Wu S, Schubert W, Terjung C, Baschiera F, Zhou L, Wu L, Lee G, Xie Y, Hui Q, Guerra J, Mertz J, Nassar K.   +14 more
europepmc   +1 more source

Soluble guanylate cyclase activator BAY 54-6544 improves vasomotor function and survival in an accelerated ageing mouse model. [PDF]

Aging Cell, 2022
Ataei Ataabadi E, Golshiri K, Jüttner AA, de Vries R, Van den Berg-Garrelds I, Nagtzaam NMA, Khan HN, Leijten FPJ, Brandt RMC, Dik WA, van der Pluijm I, Danser AHJ, Sandner P, Roks AJM.   +13 more
europepmc   +1 more source

Soluble Guanylate Cyclase Activators as Potential Novel Pad Therapeutics

JVS - Vascular Science
Shaunak Adkar, Sabina Sorondo, Mozhgan Lotfi, Sharika Bamezai, Ryan Choi, Ole Dyg Pedersen, Sisse Ostrowski, Jonas Ghouse, Henning Bundgaard, Michael Levin, Scott M. Damrauer, Nicholas J. Leeper, Derek Klarin   +12 more
doaj   +1 more source

Soluble guanylate cyclase deficiency drives retinal ganglion cell neurodegeneration with age in female mice through disrupted oxidative metabolism. [PDF]

Sci Rep
Bossardet OL, Clark KL, Wade S, Snyder LA, Mecca S, Holden JM, Almaoui E, Konety R, Ghanem GOB, Korobkina ED, Rex TS, Wareham LK.   +11 more
europepmc   +1 more source

Benign prostatic hyperplasia/obstruction ameliorated using a soluble guanylate cyclase activator. [PDF]

J Pathol, 2022
Zabbarova IV, Ikeda Y, Kozlowski MG, Tyagi P, Birder LA, Chakrabarty B, Perera SK, Dhir R, Straub AC, Sandner P, Andersson KE, Drake MJ, Fry CH, Kanai AJ.   +13 more
europepmc   +1 more source

Influence of Soluble Guanylate Cyclase on Cardiac, Vascular, and Renal Structure and Function: A Physiopathological Insight. [PDF]

Int J Mol Sci
De Feo D, Massari F, Campanella C, Livrieri A, Ciccone MM, Caldarola P, De Palo M, Scicchitano P.   +7 more
europepmc   +1 more source