Results 141 to 150 of about 467,321 (167)

A novel soluble guanylate cyclase activator, avenciguat, in combination with empagliflozin, protects against renal and hepatic injury in diabetic <i>db/db</i> mice. [PDF]

Am J Physiol Endocrinol Metab
Sharma N, Liu W, Tsai XE, Wang Z, Outtrim C, Tang A, Pieper MP, Reinhart GA, Huang Y.   +8 more
europepmc   +1 more source

Pharmacological Stimulation of Soluble Guanylate Cyclase Counteracts the Profibrotic Activation of Human Conjunctival Fibroblasts. [PDF]

Cells
Fioretto BS, Rosa I, Andreucci E, Mencucci R, Marini M, Romano E, Manetti M.   +6 more
europepmc   +1 more source

Pericyte signaling via soluble guanylate cyclase shapes the vascular niche and microenvironment of tumors. [PDF]

EMBO J
Zhu J, Yang W, Ma J, He H, Liu Z, Zhu X, He X, He J, Chen Z, Jin X, Wang X, He K, Wei W, Hu J.   +13 more
europepmc   +1 more source

Soluble guanylate cyclase stimulators and activators: new horizons in the treatment of priapism associated with sickle cell disease. [PDF]

Front Pharmacol
Pereira DA, Silveira THR, Calmasini FB, Silva FH.   +3 more
europepmc   +1 more source

Soluble guanylate cyclase stimulators for heart failure: a network meta-analysis and subgroup analyses of reduced and preserved ejection fraction. [PDF]

Egypt Heart J
Abuelazm MT, Attia A, Abdelnabi M, Jafar U, Almaadawy O, Elzeftawy MA, Mahmoud A, Albakri K, Abdelazeem B.   +8 more
europepmc   +1 more source

Safety, tolerability, pharmacokinetics, and pharmacodynamics of a soluble guanylate cyclase stimulator, HEC95468, in healthy volunteers: a randomized, double-blinded, placebo-controlled phase 1 trial. [PDF]

Front Pharmacol
Gui YZ, Wang W, Wu QQ, Ding QC, Qian HJ, Lu QB, Zhang YJ, Zhuang YL, Deng L, Zuo YL, Luo L, Jia JY.   +11 more
europepmc   +1 more source

Mitochondrial soluble adenylyl cyclase (sAC) cooperates with membrane adenylyl cyclase in the regulation of complex I turnover and activity.

, 2012
Domenico De Rasmo, Sergio Papa Mitochondrial soluble adenylyl cyclase sAC cooperates with membrane adenylyl cyclase in the regulation of complex I turnover, Giuseppe Capitanio, activity, Arcangela Santeramo, Anna Signorile   +5 more
core  

Expression and activity of soluble guanylate cyclase in injury and repair of anti-thy1 glomerulonephritis [PDF]

Kidney International, 2004
Expression and activity of soluble guanylate cyclase in injury and repair of anti-thy1 glomerulonephritis.BackgroundActivation of soluble guanylate cyclase and generation of cyclic 3′,5′-guanosine monophosphate (cGMP) is the main signal transducing event
Harm Peters, Susanne Kron, Sebastian Martini   +2 more
exaly   +2 more sources

Stimulation of soluble guanylate cyclase slows progression in anti-thy1-induced chronic glomerulosclerosis [PDF]

Kidney International, 2005
Stimulation of soluble guanylate cyclase slows progression in anti-thy1-induced chronic glomerulosclerosis.BackgroundA critical role of soluble guanylate cyclase and nitric oxide-dependent cyclic 3′,5′-guanosine monophosphate (cGMP) production for ...
Hiroshi Kawachi, Harm Peters, Susanne Kron   +2 more
exaly   +2 more sources

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Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease

Circulation, 2011
Pal Pacher, Johannes-Peter Stasch, Oleg V Evgenov   +2 more
exaly