Results 291 to 300 of about 460,443 (348)

A Comparison of the Mechanical Properties of ECM Components and Synthetic Self‐Assembling Peptides

Advanced Healthcare Materials, Volume 14, Issue 11, April 25, 2025.
Self‐assembling peptide hydrogels are increasingly utilized in biomedical applications. The authors review the key mechanical properties of these structures across multiple size scales and compare them to that of native extracellular matrix components, which are found to display a much wider range of structural attributes.
Alex Hartley, Philip Michael Williams, Alvaro Mata   +2 more
wiley   +1 more source

Soluble PD-L1: From Immune Evasion to Cancer Therapy. [PDF]

Life (Basel)
Dragu D, Necula LG, Bleotu C, Diaconu CC, Chivu-Economescu M.   +4 more
europepmc   +1 more source

FXa‐Responsive Hydrogels to Craft Corneal Endothelial Lamellae

Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
This study introduces a sacrificial, multicomponent biohybrid hydrogel system enabling stable scaffold‐free tissue engineering. Its efficacy is demonstrated through the ex vivo development, detachment, and transplantation of human corneal endothelial lamellae, achieving clinically relevant sizes for Descemet Membrane Endothelial Keratoplasty.
Mikhail V. Tsurkan, Juliane Bessert, Rabea Selzer, Sarah D. Tsurkan, Dagmar Pette, Manfred F. Maitz, Petra B. Welzel, Carsten Werner   +7 more
wiley   +1 more source

Cytokines are the Basis of the Development and Suppression of Inflammation in Atherosclerosis. [PDF]

Rev Cardiovasc Med
Blagov AV, Churov AV, Starodubtseva IA, Kovyanova TI, Pecherina TB, Sukhorukov VN.   +5 more
europepmc   +1 more source

Iron‐MOFs for Biomedical Applications

Advanced Healthcare Materials, Volume 14, Issue 8, March 25, 2025.
This review introduces the unique properties of iron‐based metal–organic frameworks (Fe‐MOFs), the advances in synthesis and formulation, and their state‐of‐the‐art applications in biomedicine. It discusses the challenges in transitioning Fe‐MOFs from research to clinical use, emphasizing the need for eco‐friendly production methods, and a deeper ...
Zhihao Yu, Mathilde Lepoitevin, Christian Serre   +2 more
wiley   +1 more source

The Role of NK Cells in Cancer Immunotherapy: Mechanisms, Evasion Strategies, and Therapeutic Advances. [PDF]

Biomedicines
Morcillo-Martín-Romo P, Valverde-Pozo J, Ortiz-Bueno M, Arnone M, Espinar-Barranco L, Espinar-Barranco C, García-Rubiño ME.   +6 more
europepmc   +1 more source

Leveraging Organ‐on‐Chip Models to Investigate Host–Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease

Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
The challenges of studying inflammatory bowel disease (IBD), highlighting limitations of traditional 2D cell cultures and animal models are discussed here. It introduces human intestine organ‐on‐chip (OoC) models as a promising alternative, capable of more accurately mimicking the intestinal microenvironment.
Tim Kaden, Raquel Alonso‐Román, Johannes Stallhofer, Mark S. Gresnigt, Bernhard Hube, Alexander S. Mosig   +5 more
wiley   +1 more source

Plasma Soluble Progenitor Cell Receptors as Biomarkers for Severe Anemia Among Malaria-Infected Pediatrics: A Prospective Study in Ghana. [PDF]

Health Sci Rep
Nkansah C, Appiah SK, Osei-Boakye F, Appiah-Kubi E, Abbam G, Daud S, Derigubah CA, Bani SB, Banyeh M, Mensah K, Tater R, Mensah JO, Natornaa A, Adjei I, Tanko MM, Amankwaa G, Selleh PK, Aboagye SB, Chima OK, Kpangkpari SM, Ottah P, Boadi E, Quansah Y, Chukwurah EF, Ukwah BN, Usanga VU.   +25 more
europepmc   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

Redirecting immune signaling with cytokine adaptors. [PDF]

Nat Commun
Abhiraman GC, Householder KD, Rodriguez GE, Glassman CR, Saxton RA, Breuer CB, Wilson SC, Su L, Yen M, Hsu C, Pillarisetty VG, Reticker-Flynn NE, Garcia KC.   +12 more
europepmc   +1 more source