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Variations in serum soluble IL‐2 receptor concentration

Pediatric Allergy and Immunology, 1994
Soluble interleukin‐2 receptor (sIL‐2R) concentrations were measured in the sera of 18 healthy adult volunteers, 40 healthy children aged 5 months ‐ 16 years 8 months and cord blood from 10 babies, using two commercially available ELISA kits (T‐cell Sciences and Serotec).
A C, Jones   +3 more
openaire   +2 more sources

Soluble IL‐2 receptors in acute and subacute encephalitis

Annals of Neurology, 1987
AbstractElevated levels of soluble interleukin‐2 receptors were present in the serum from patients with acute primary and postinfectious encephalitis and subacute sclerosing panencephalitis. In addition, soluble interleukin‐2 receptors were detected in the cerebrospinal fluid from patients with acute primary encephalitis.
B, Boutin   +5 more
openaire   +2 more sources

Neuroleptic treatment increases soluble IL-2 receptors and decreases soluble IL-6 receptors in schizophrenia

European Archives of Psychiatry and Clinical Neuroscience, 1997
The cytokines interleukin-2 (IL-2) and interleukin-6 (IL-6) increase during immune activation, they are released from activated astrocytes and microglial cells in the central nervous system (CNS), and they are able to enhance the catecholaminergic neurotransmission. This study focused on the soluble receptors of IL-2 and IL-6 (sIL-2R, sIL-6R) as a part
N, Müller   +4 more
openaire   +2 more sources

MIXED LYMPHOCYTE REACTION-INDUCED RELEASE OF SOLUBLE IL-2 RECEPTOR

Transplantation, 1991
We studied the release of soluble interleukin 2 receptor (sIL-2R) by PBMC in mixed lymphocyte reaction (MLR) in order to clarify the significance of high plasma levels of sIL-2R in transplant patients undergoing rejection. Levels of sIL-2R were shown to increase progressively after the first day of the MLR and reached their peak on day 5.
D, Degiannis   +4 more
openaire   +2 more sources

Chitotriosidase and soluble IL‐2 receptor: Comparison of two markers of sarcoidosis severity

Scandinavian Journal of Clinical and Laboratory Investigation, 2008
Sarcoidosis is a multisystemic granulomatous disease with an unpredictable clinical course characterized by accumulation of activated proliferating T lymphocytes and mononuclear phagocytes in affected organs.The aims of this study were to describe the clinical, radiological and immunological features of a population of sarcoidosis patients followed at ...
BARGAGLI, E.   +7 more
openaire   +4 more sources

Serum soluble interleukin 2 (IL-2) receptor (sIL-2R) in differentiated thyroid carcinoma

Journal of Endocrinological Investigation, 1994
Increased concentrations of serum soluble interleukin-2 (IL-2) receptor (sIL-2R), a marker of T-lymphocyte activation, have been found in several metastatic solid tumors. To our knowledge, no information is available on serum sIL-2R in differentiated thyroid carcinoma (DTC).
MARIOTTI, STEFANO   +7 more
openaire   +4 more sources

Clinical utility of soluble IL-2 receptor alpha in haemophagocytic lymphohistiocytosis

Pathology, 2012
Haemophagocytic lymphohistiocytosis (HLH) is characterised by lymphocyte and macrophage activation, resulting in fever, hepa-tosplenomegaly, coagulopathy, cytopenias and other features of inflammation. Diagnosis of HLH can be established when five of eight criteria, one of which is elevated soluble IL2-receptor-alpha (sIL2-Ra), are fulfilled.1 ...
Kuang-Chih Hsiao   +4 more
openaire   +1 more source

Interleukin 2 (IL 2) inhibitor in rheumatoid synovial fluid: Correlation with prognosis and soluble IL 2 receptor levels

Journal of Clinical Immunology, 1990
A soluble activity inhibiting over 50% of the CTLL-2 cell line response to recombinant human interleukin 2 (IL 2) was found in 17 of 29 (59%) rheumatoid synovial fluids. To study the prognosis value of this activity, 16 rheumatoid synovial fluids were collected before a radiation synovectomy of the knee with 7 mCi of 90Yt. Patients with a good clinical
P, Miossec   +5 more
openaire   +2 more sources

The role of interleukin 2 (IL-2) and serum-soluble IL-2 receptor cells in idiopathic IgA nephropathy

Clinical Immunology and Immunopathology, 1992
Interleukin 2 (IL-2) plays a central role in the immune response and may be involved in the derangement of cellular immunoregulation of idiopathic IgA nephropathy (IgAN). The aim of this study was to investigate the serum levels and production of IL-2 from peripheral blood mononuclear cells (PBMC) and the distribution of IL-2 receptor cells and serum ...
M, Parera   +3 more
openaire   +2 more sources

[The soluble IL-2 receptor in malignant hemopathies].

Recenti progressi in medicina, 1993
The increase in the serum levels of the IL-2 receptors is due to its release both in vivo and in vitro from activated cells or neoplastic cells expressing it constitutively. The diagnostic, prognostic and physiopathologic significance of the sIL-2R was investigated by testing the serum of 271 haemopathic patients in various stages of the disease.
S, Rupoli   +8 more
openaire   +1 more source

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