Humanized Antibodies Targeting Ectodomains of IL-6R and GP130 Suppress IL-6/STAT3 Signalling and Tumour Growth in Breast Cancer Models. [PDF]
Pereira SD +10 more
europepmc +1 more source
Interleukin-6 and soluble interleukin-6 receptor levels in posttraumatic stress disorder: associations with lifetime diagnostic status and psychological context. [PDF]
Newton TL +3 more
europepmc +1 more source
This study innovates a Ca2+‐responsive hydrogel dressing that releases AIE photosensitizers on‐demand. Low Ca2+ enhances bacterial hyaluronidase (HAase) activity, degrading hyaluronic acid dressing to trigger antibacterial ROS release, while high Ca2+ inhibits HAase, preventing overdosing.
Rongwei Cui +12 more
wiley +1 more source
The role of interleukin-6 in diabetic retinal disease: pathophysiology and therapeutic targeting. [PDF]
Harlow REA +4 more
europepmc +1 more source
Schematic illustration of the effect of microneedles incorporating cerium‐based MOF loading dihydrocapsaicin (MN‐MOF@DHC) to scavenge reactive oxygen species (ROS) generation, beanti‐inflammatory, inhibit the apoptosis of endothelial cells (ECs), promote angiogenesis, and accelerate diabetic wound healing. ABSTRACT Diabetic foot ulcers (DFUs) present a
Yuxu Wu +11 more
wiley +1 more source
Synovial Fluid Biomarkers Associated With Anterior Cruciate Ligament Injury and Reconstruction: A Systematic Review. [PDF]
Touhey DC +7 more
europepmc +1 more source
Quadruplex Bioactive FAND for Treating Acute Liver Failure Induced by Acetaminophen or Hepatectomy
This work developed a bioactive quadruplex FANDHP@FuEVs with intrinsic inflammation‐targeting properties of M2‐EVs and MSC‐EVs, harnessing the synergistic biological activities by leveraging four natural active components—M2‐EVs, MSC‐EVs, HGF, and PPC—to deliver pleiotropic therapies, including antioxidant, anti‐inflammatory, pro‐regenerative, and M1 ...
Meng Sun +10 more
wiley +1 more source
A schematic illustration of an engineered nature‐based sonosensitizer enables early‐stage high‐power ultrasound to generate substantial reactive oxygen species for antibacterial effects and late‐stage low‐power sono‐ionic therapy for infected bone repair, infected wound biofilm therapy, and wound regeneration.
Liang Ma +13 more
wiley +1 more source
Tocilizumab as a novel bridging therapy for surgery in dedifferentiated liposarcoma complicated by paraneoplastic leukemoid reaction, severe anemia, and thrombocytopenia: a case report. [PDF]
Li J +6 more
europepmc +1 more source
Pectin, a versatile natural polymer, is extracted through conventional and emerging green extraction methods, offering multifunctional bioactive properties useful in food, pharmaceutical, and environmental applications. ABSTRACT Pectin, a molecular tapestry woven from diverse polysaccharides, holds a pivotal role across food, pharmaceutical, and ...
Afra Anika Rafique +3 more
wiley +1 more source

