Results 81 to 90 of about 202,290 (315)
Advanced Science, EarlyView.A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu +17 more
wiley +1 more source
Original paper Predictors of juvenile idiopathic arthritis course
Rheumatology, 2015 Introduction : Juvenile idiopathic arthritis (JIA) is a heterogeneous group of inflammatory diseases of joints in children with various and often unfavourable prognosis.
Jaryna J. Bojko +2 more
doaj +1 more source
Advanced Science, EarlyView.This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka +4 more
wiley +1 more source
Indian Heart Journal, 2018 Cardiovascular diseases are leading cause of mortality and morbidity, and are responsible for 1 out of every 6 deaths in the United States.1 Cardiac remodeling is an important determinant of long term outcomes and occurrence of heart failure (HF).
Aditi Dattagupta, Sathyamurthy Immaneni
doaj +1 more source
Interleukin-6 and Soluble Interleukin-6 Receptor Levels as Markers of Disease Extent and Prognosis in Neuroblastoma [PDF]
Clinical Cancer Research, 2008 Abstract Purpose: To explore the relationships between interleukin-6 (IL-6) and soluble IL-6 receptor (sIL-6R) levels and disease extent and clinical outcome in childhood neuroblastoma. Experimental Design: Pretreatment peripheral blood (PB; n = 53) and bone marrow (n = 18) samples from patients with neuroblastoma were ...
Rachel A, Egler +3 more
openaire +2 more sources
Advanced Science, EarlyView.It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou +8 more
wiley +1 more source
Serum levels of interleukin-6 are not dependent on the kidney function
Mediators of Inflammation, 1992 Interleukin-6, also named B-cell stimulatory factor, is a glycoprotein with a molecular weight of 26 kDa. Increased serum levels of interleukin-6 (IL-6) are found in several disease conditions.
L. Nässberger
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Archives of Medical Science, 2016 Introduction: Increased expression of interleukin-6 (IL-6) has been described in left ventricular dysfunction in the course of chronic heart failure.
Katarzyna Ptaszynska-Kopczynska +9 more
doaj +1 more source
Advanced Science, EarlyView.A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li +6 more
wiley +1 more source
Interleukin 6 and 8 Levels in Plasma and Fibroblast Cultures in Psoriasis
Mediators of Inflammation, 2006 Fibroblasts have been implicated in psoriatic inflammatory processes. The aim of the study was to evaluate soluble interleukin 2 receptor (sIL-2R), interleukin 6 (IL-6), and interleukin 8 (IL-8) plasma levels in psoriatic patients and IL-6 and IL-8 ...
Anna Zalewska +5 more
doaj +2 more sources