Results 51 to 60 of about 224,815 (311)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Influence of temperature, concentration and shear rate on the rheological behavior of malay apple (Syzygium malaccense) juice

Brazilian Journal of Food Technology
Summary The aim of this study was to evaluate the rheological behavior of malay apple, a traditional Amazonian fruit with high bioactive properties, at different temperatures and soluble solids concentrations.
Pedro Henrique Santos, Luiza Helena Meller da Silva, Antônio Manoel da Cruz Rodrigues, José Antonio Ribeiro de Souza   +3 more
doaj   +1 more source

Identifying Consumer Perceptions of Fresh-market Blackberries [PDF]

, 2019
Blackberries are grown worldwide for commercial fresh markets, but there is limited information on consumer perceptions of this fruit. In this study, physiochemical and consumer sensory attributes of three Arkansas-grown fresh-market blackberry genotypes
Dunteman, Aubrey
core   +2 more sources

Diffusivity and solubility of oxygen in solid palladium [PDF]

Journal of Materials Science, 2009
The solid solubility cO of oxygen in palladium in equilibrium with gaseous oxygen has been determined from absorption-desorption experiments for temperatures T of 1123 and 1173 K and oxygen partial pressures \( p_{{{\text{O}}_{2} }} \) between 2.7 × 103 and 4.0 × 104 Pa.
Gegner, J., Hoerz, G., Kirchheim, Reiner
openaire   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Comparative Nutritional and Antioxidant Compounds of Organic and Conventional Vegetables during the Main Market Availability Period

Nitrogen, 2021
Seven winter and five summer vegetables produced under organic and conventional systems were collected from a supermarket seven times between January and April and between July and October for winter and summer vegetables, respectively, and their ...
Constantinos Roumeliotis, Anastasios S. Siomos, Dimitrios Gerasopoulos   +2 more
doaj   +1 more source

PHYSICOCHEMICAL PROPERTIES AND ACCEPTANCE OF JELLY AND NECTAR OF ARAZA AND PAPAYA [PDF]

, 2012
The main objective of this work was to evaluate the acceptance of jelly and nectars made from araza (Eugenia stipitata Mc Vaugh) and papaya. The following percentages of araza and papaya were, respectively, used: 50:50; 40:60; 30:70 and 20:80.
Baptista, F.J., Chaves, M.A., Pinto, E.G., Sacramento, C.K., Soares, E.C., Soares, R.D.   +5 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Constituent Loads and Trends in the Upper Illinois River Watershed and Upper White River Basin: 2015 October through 2018 September [PDF]

, 2019
The Arkansas Natural Resources Commission (ANRC) identified two priority hydrologic unit code (HUC) 8 watersheds, the Upper White River Basin (UWRB; HUC 11010001) and the Upper Illinois River Watershed (UIRW; 11110103), in northwest Arkansas.
Haggard, Brian E., Scott, Erin E.
core   +2 more sources

REVIEW ARTICLE: SOLUBILITY ENHANCEMENT BY SOLID DISPERSION

International Journal of Current Pharmaceutical Research, 2017
Enhancement of solubility, dissolution rate and bioavailability of the drug is a very challenging task in drug development, nearly 40% of the new chemical entities currently being discovered are poorly water soluble drugs. The solubility behaviour of the drugs remains one of the most challenging aspects in formulation development.
D. M. Shinkar, A. N. Patil, R. B. Saudagar   +2 more
openaire   +2 more sources