Results 61 to 70 of about 686,634 (303)
Determining the number of replicates required to produce statistically testable results based on previously conducted tests is important to minimize labor costs via the use of existing information.
Bernardo Bezerra de Araújo Junior +4 more
doaj +1 more source
Solubility enhancement and solid-state characterisation [PDF]
The concept of “molecular inflation”1, where the molecular weight of patented and marketed drugs is increasing (as is their molecular complexity), is now demonstrated to be a reality.
openaire +2 more sources
Nitrogen solubility in solid niobium [PDF]
The solubility of nitrogen in solid niobium was measured in the temperature range 2473 to 2673 K using electromagnetic levitation technique. Nitrogen solution obeyed Sieverts’ law. The standard heat and entropy of solution of nitrogen in niobium were found to be −1.99 × 105 kJ/kg-atom and −52.3 kJ/kg-atom K, respectively.
M. Alam, T. DebRoy
openaire +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Fruit samples were analysed to investigate the suitability of Fourier transform near infrared spectroscopy (FT-NIR) for the rapid discrimination of elderberry genotypes.
Virág Csorba +3 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Performance of juice and wine grape cultivars in different training systems
The increase of rural tourism activities has led growers to use different grape cultivars for the production of wine and/or juice. Thus, the aim of this study was to evaluate the phytotechnical characteristics of grapevines and physicochemical ...
Mário José Pedro Júnior +2 more
doaj +1 more source
Improvement in solubility of poor water-soluble drugs by solid dispersion
This article is intended to combine recent literature on solid dispersion technology for solubility enhancement with special emphasis on mechanism responsible for the same by solid dispersion, various preparation methods, and evaluation parameters. Solubility behavior is the most challenging aspect for various new chemical entities as 60% of the new ...
Sareen, Swati +2 more
openaire +3 more sources
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Rootstock-scion interaction:5. Effect on the evolution of Cabernet Sauvignon grape ripening
The rootstock effect on grapevine yield components, grape must and wine composition and wine sensory characteristics were evaluated in previous studies.
Alberto Miele, Luiz Antenor Rizzon
doaj +1 more source

