Results 11 to 20 of about 13,720 (213)

Soluble ST2 Blocks Interleukin-33 Signaling in Allergic Airway Inflammation [PDF]

Journal of Biological Chemistry, 2007
The ST2 gene produces a soluble secreted form and a transmembrane form, referred to as soluble ST2 and ST2L, respectively. A recent study has reported that interleukin (IL)-33 is a specific ligand of ST2L and induces production of T helper type 2 (Th2) cytokines. Although soluble ST2 is highly produced in sera of asthmatic patients and plays a critical
Hiroko, Hayakawa, Morisada, Hayakawa, Akihiro, Kume, Shin-ichi, Tominaga   +3 more
openaire   +4 more sources

Toll/Interleukin-1 receptor member ST2 exhibits higher soluble levels in type 2 diabetes, especially when accompanied with left ventricular diastolic dysfunction [PDF]

Cardiovascular Diabetology, 2011
Background Soluble ST2, a member of the of the Toll/IL-1 superfamily, is a novel biomarker with exceptional predictive value in heart failure and myocardial infarction- related mortality as well as in acute dyspneic states.
Fousteris Evangelos, Melidonis Andreas, Panoutsopoulos George, Tzirogiannis Konstantinos, Foussas Stefanos, Theodosis-Georgilas Anastasios, Tzerefos Stavros, Matsagos Spiridon, Boutati Eleni, Economopoulos Theofanis, Dimitriadis George, Raptis Sotirios   +11 more
doaj   +4 more sources

Serum Soluble ST2

Journal of the American College of Cardiology, 2010
Weir, Robin A.P., Miller, Ashley M., Murphy, Grace E.J., Clements, Suzanne, Steedman, Tracey, Connell, John M.C., McInnes, Iain B., Dargie, Henry J., McMurray, John J.V.   +8 more
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ST2 in patients with severe aortic stenosis and heart failure

Cardiology Journal, 2021
BACKGROUND: ST2 is a circulating biomarker that is well established for predicting outcome in heart failure (HF). This is the first study to look at ST2 concentrations in optimally treated patients with stable but significant left ventricular systolic ...
Andrew Cai, Alejandra Miyazawa, Nicholas Sunderland, Susan E. Piper, Thomas G.J. Gibbs, Duolao Wang, Sadie Redding, George Amin-Youseff, Olaf Wendler, Jonathan Byrne, Philip A. MacCarthy, Ajay M. Shah, Theresa A. McDonagh, Rafał Dworakowski   +13 more
doaj   +1 more source

Prognostic value of serum soluble ST2 in professional athletes (Valor pronóstico de ST2 soluble en suero en deportistas profesionales)

Retos, 2021
Background: The predictive value of serum soluble ST2 (sST2) biomarker for diagnostics of cardiovascular pathologies is still poorly understood as well as the role of psychological stress on the risk of heart disease. Aim: This study aimed at determining the diagnostic significance of the sST2 level in athletes involved in speed-strength sports.
Madina Baurzhan, Salim Berkinbayev, Kuat Abzaliyev, Zhanar Andassova, Yrysbubu Anvarbekova, Symbat Abzaliyeva, Karashash Absatarova, Shynar Tanabayeva, Gulnar Rakhimbekova, Ildar Fakhradiyev   +9 more
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Performance Evaluation of AFIAS ST2 and Ichroma ST2 Assays in Comparison with Presage ST2 Assay

Reviews in Cardiovascular Medicine, 2023
Background: Elevated soluble suppression of tumorigenicity 2 (sST2) levels may predict mortality in heart failure (HF) patients. The AFIAS ST2 assay (AFIAS ST2, Boditech Med Inc., Chuncheon, Korea) and ichroma ST2 assay (ichroma ST2, Boditech Med Inc ...
Hanah Kim, Tae-Hwan Lee, Mina Hur, Hyun-Joong Kim, Hyun Suk Yang, Kyeong Ryong Lee, Salvatore Di Somma   +6 more
doaj   +1 more source

A Multi-marker Model for Predicting Decompensated Heart Failure in Patients with Prior Acute Myocardial Infarction [PDF]

, 2020
The aim of the study was to assess the prognostic value of determining the plasma concentration of NT-proBNP and ST2 in the patients with decompensated HF and prior acute myocardial infarction and their combination in this category of patients.Materials ...
Levandovska, K. (Khrystyna)
core   +3 more sources

Pulmonary Production of Soluble ST2 in Heart Failure [PDF]

Circulation: Heart Failure, 2018
Background: Serum concentrations of ST2 (interleukin-1 receptor-like 1) represent a meaningful prognostic marker in cardiac diseases. Production of soluble ST2 (sST2) may be partially extracardiac. Identification of sST2 sources is relevant to design strategies for modulating its signaling.
Domingo A, Pascual-Figal, Maria T, Pérez-Martínez, Maria C, Asensio-Lopez, Jesús, Sanchez-Más, Maria E, García-García, Carlos M, Martinez, Miriam, Lencina, Ruben, Jara, James L, Januzzi, Antonio, Lax   +9 more
openaire   +2 more sources

Soluble ST2 predicts elevated SBP in the community [PDF]

Journal of Hypertension, 2013
Soluble ST2 (sST2) is an emerging prognostic biomarker in patients with existing cardiovascular disease. ST2 and its ligand, interleukin-33 (IL-33), are expressed in endothelial cells, and may play an important role in the development of early atherosclerosis and vascular biology.
Jennifer E, Ho, Martin G, Larson, Anahita, Ghorbani, Susan, Cheng, Ramachandran S, Vasan, Thomas J, Wang, James L, Januzzi   +6 more
openaire   +2 more sources

Role of the IL-33/ST2/p38 signaling pathway in the immune response of corneal epithelial cells to Aspergillus fumigatus infection [PDF]

International Journal of Ophthalmology, 2019
AIM: To investigate the expression of interleukin (IL)-33 in the cornea and human corneal epithelial cells (HCECs) exposed to Aspergillus fumigatus (A. fumigatus), and to determine the function of IL-33/ST2/p38 signaling pathway in the immune response of
Jia You, Jing Lin, Yi-Fan Zhou, Xu-Dong Peng, Hong He, Cui Li, Guo-Qiang Zhu, Xue-Qi Zhao, Gui-Qiu Zhao   +8 more
doaj   +1 more source