Results 11 to 20 of about 6,809 (170)

Soluble ST2 and Galectin-3 and Progression of CKD [PDF]

Kidney International Reports, 2019
Introduction: Cardiac biomarkers soluble ST2 (sST2) and galectin-3 may reflect cardiac inflammation and fibrosis. It is plausible that these mechanisms may also contribute to the progression of kidney disease.
Mariam L. Alam, Ronit Katz, Keith A. Bellovich, Zeenat Y. Bhat, Frank C. Brosius, Ian H. de Boer, Crystal A. Gadegbeku, Debbie S. Gipson, Jennifer J. Hawkins, Jonathan Himmelfarb, Bryan R. Kestenbaum, Matthias Kretzler, Cassianne Robinson-Cohen, Susan P. Steigerwalt, Courtney Tuegel, Nisha Bansal   +15 more
doaj   +3 more sources

Soluble ST2 levels are associated with bleeding in patients with severe Leptospirosis. [PDF]

PLoS Neglected Tropical Diseases, 2009
Severe leptospirosis features bleeding and multi-organ failure, leading to shock and death. Currently it is assumed that both exaggerated inflammation and immune suppression contribute to mortality in sepsis. Indeed, several proinflammatory cytokines are
Jiri F P Wagenaar, M Hussein Gasem, Marga G A Goris, Mariska Leeflang, Rudy A Hartskeerl, Tom van der Poll, Cornelis van 't Veer, Eric C M van Gorp   +7 more
doaj   +4 more sources

A role for soluble ST2 in vascular remodeling associated with obesity in rats. [PDF]

PLoS ONE, 2013
BackgroundThe function of the Interleukin-33 (IL-33)/ST2 system has been mainly investigated on immunological aspects, but recent data suggest that this pathway plays also an important role in cardiovascular system and adipose tissue.
Ernesto Martínez-Martínez, María Miana, Raquel Jurado-López, Elodie Rousseau, Patrick Rossignol, Faiez Zannad, Victoria Cachofeiro, Natalia López-Andrés   +7 more
doaj   +5 more sources

Soluble ST2 Is a Sensitive and Specific Biomarker for Fulminant Myocarditis. [PDF]

J Am Heart Assoc, 2022
Background The aim of the study was to identify biomarkers that can facilitate early diagnosis and treatment of fulminant myocarditis (FM) in order to reduce mortality. Methods and Results First, the expression profiles of circulating cytokines were determined in the plasma samples ...
Wang J, He M, Li H, Chen Y, Nie X, Cai Y, Xie R, Li L, Chen P, Sun Y, Li C, Yu T, Zuo H, Cui G, Miao K, Zhao C, Jiang J, Heidecker B, Barnett O, Maisel A, Chen C, Wang DW.   +21 more
europepmc   +4 more sources

ST2 in patients with severe aortic stenosis and heart failure

Cardiology Journal, 2021
BACKGROUND: ST2 is a circulating biomarker that is well established for predicting outcome in heart failure (HF). This is the first study to look at ST2 concentrations in optimally treated patients with stable but significant left ventricular systolic ...
Andrew Cai, Alejandra Miyazawa, Nicholas Sunderland, Susan E. Piper, Thomas G.J. Gibbs, Duolao Wang, Sadie Redding, George Amin-Youseff, Olaf Wendler, Jonathan Byrne, Philip A. MacCarthy, Ajay M. Shah, Theresa A. McDonagh, Rafał Dworakowski   +13 more
doaj   +1 more source

Pulmonary Production of Soluble ST2 in Heart Failure [PDF]

Circulation: Heart Failure, 2018
Background: Serum concentrations of ST2 (interleukin-1 receptor-like 1) represent a meaningful prognostic marker in cardiac diseases. Production of soluble ST2 (sST2) may be partially extracardiac. Identification of sST2 sources is relevant to design strategies for modulating its signaling.
Pascual Figal, Domingo Andrés, Pérez Martínez, María T, Asensio López, María del Carmen, Sánchez Mas, Jesús, García García, María E, Martínez, Carlos M, Lencina, Miriam, Jara, Ruben, Januzzi, James L, Lax Pérez, Antonio Manuel   +9 more
openaire   +2 more sources

Performance Evaluation of AFIAS ST2 and Ichroma ST2 Assays in Comparison with Presage ST2 Assay

Reviews in Cardiovascular Medicine, 2023
Background: Elevated soluble suppression of tumorigenicity 2 (sST2) levels may predict mortality in heart failure (HF) patients. The AFIAS ST2 assay (AFIAS ST2, Boditech Med Inc., Chuncheon, Korea) and ichroma ST2 assay (ichroma ST2, Boditech Med Inc ...
Hanah Kim, Tae-Hwan Lee, Mina Hur, Hyun-Joong Kim, Hyun Suk Yang, Kyeong Ryong Lee, Salvatore Di Somma   +6 more
doaj   +1 more source

Clinical value of soluble ST2 in cardiology

Advances in Clinical and Experimental Medicine, 2020
We are constantly looking for new parameters and markers that can help in the assessment of patients with various diseases, including cardiac disorders; this can translate into better care and improved prognosis. Suppression of tumorigenicity 2 (ST2) has recently gained interest as a potential biomarker in many fields: it is involved in many ...
Magdalena Dudek, Marta Kałużna-Oleksy, Jacek Migaj, Ewa Straburzyńska-Migaj   +3 more
openaire   +2 more sources

Soluble ST2 predicts elevated SBP in the community [PDF]

Journal of Hypertension, 2013
Soluble ST2 (sST2) is an emerging prognostic biomarker in patients with existing cardiovascular disease. ST2 and its ligand, interleukin-33 (IL-33), are expressed in endothelial cells, and may play an important role in the development of early atherosclerosis and vascular biology.
Jennifer E, Ho, Martin G, Larson, Anahita, Ghorbani, Susan, Cheng, Ramachandran S, Vasan, Thomas J, Wang, James L, Januzzi   +6 more
openaire   +2 more sources

Role of the IL-33/ST2/p38 signaling pathway in the immune response of corneal epithelial cells to Aspergillus fumigatus infection [PDF]

International Journal of Ophthalmology, 2019
AIM: To investigate the expression of interleukin (IL)-33 in the cornea and human corneal epithelial cells (HCECs) exposed to Aspergillus fumigatus (A. fumigatus), and to determine the function of IL-33/ST2/p38 signaling pathway in the immune response of
Jia You, Jing Lin, Yi-Fan Zhou, Xu-Dong Peng, Hong He, Cui Li, Guo-Qiang Zhu, Xue-Qi Zhao, Gui-Qiu Zhao   +8 more
doaj   +1 more source