Results 21 to 30 of about 402 (126)
Journal for ImmunoTherapy of Cancer, 2023 Background Chimeric antigen receptor (CAR)-T cell-based immunotherapy constitutes a revolutionary advance for treatment of relapsed/refractory hematological malignancies.
Alvaro Urbano-Ispizua +17 more
doaj +1 more source
Serum Soluble ST2 and Diastolic Dysfunction in Hypertensive Patients [PDF]
Disease Markers, 2017 Background. Echocardiographic evaluation of left ventricular (LV) structural and functional alterations in hypertension has some limitations, potentially overcome by using biomarkers. ST2, a prognostic biomarker for heart failure and myocardial infarction patients, was less studied in hypertension. Aim.
Anca Daniela Farcaş +5 more
openaire +2 more sources
The Prognostic Value of Soluble ST2 in Adults with Pulmonary Hypertension [PDF]
Journal of Clinical Medicine, 2019 Soluble ST2 (sST2) is upregulated in response to myocardial stress and may serve as biomarker in adults with pulmonary hypertension (PH). This prospective cohort study investigated sST2 levels and its association with echocardiographic and hemodynamic measures, and adverse clinical outcomes in adults with PH of different etiologies.
Laurie W. Geenen +7 more
openaire +3 more sources
Soluble ST2 Testing: A Promising Biomarker in the Management of Heart Failure
Arquivos Brasileiros de Cardiologia, 2016 ST2 is a member of the interleukin-1 receptor family biomarker and circulating soluble ST2 concentrations are believed to reflect cardiovascular stress and fibrosis.
Humberto Villacorta, Alan S. Maisel
doaj +1 more source
Pifu-xingbing zhenliaoxue zazhi, 2020 Objective: To investigate the clinical significance of interleukin-33(IL-33) and soluble ST2 (sST2) in patients with vitiligo. Methods: The serum concentrations of IL-33 and sST2 were determined by enzyme linked immunosorbent assay (ELISA) respectively ...
Li YANG, Dong-qing LU, Han MA
doaj +1 more source
Correlation of Suppression of Tumourigenicity 2 with hsCRP, NT-proBNP and Left Ventricular Ejection Fraction in Patients with Myocardial Infarction [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Soluble Suppression of Tumourigenicity 2 (sST2) represents a clinically relevant biomarker and has predictive evidence in acute Myocardial Infarction (MI) and predicts cardiovascular death and risk of heart failure development in these ...
Mainuddin Khan +4 more
doaj +1 more source
The Diagnostic Value of Soluble ST2 in Heart Failure: A Meta-Analysis [PDF]
Frontiers in Cardiovascular Medicine, 2021 Objective: The diagnostic performance of soluble suppression of tumorigenicity (sST2) in heart failure (HF) had been investigated in multiple studies, but the results were inconsistent. This meta-analysis evaluated the diagnostic value of sST2 in HF.Methods: Pubmed, Web of Science, Embase, and Cochrane Library databases were searched until March 2021 ...
Chaojun Yang +6 more
openaire +3 more sources
Soluble ST2 suppresses the effect of interleukin-33 on lung type 2 innate lymphoid cells
Biochemistry and Biophysics Reports, 2016 Type 2 innate lymphoid cells (ILC2) in lungs produce interleukin (IL)-5 and IL-13 in response to IL-33 and may contribute to the development of allergic diseases such as asthma.
Hiroko Hayakawa +2 more
doaj +1 more source
The miRNA199a/SIRT1/P300/Yy1/sST2 signaling axis regulates adverse cardiac remodeling following MI
Scientific Reports, 2021 Left ventricular remodeling following myocardial infarction (MI) is related to adverse outcome. It has been shown that an up-regulation of plasma soluble ST2 (sST2) levels are associated with lower pre-discharge left ventricular (LV) ejection fraction ...
Maria Carmen Asensio-Lopez +5 more
doaj +1 more source
A novel interleukin 33/ST2 signaling regulates inflammatory response in human corneal epithelium. [PDF]
PLoS ONE, 2013 Interleukin (IL) 33, a member of IL-1 cytokine family, is well known to promote Th2 type immune responses by signaling through its receptor ST2. However, it is not clear whether ST2 is expressed by mucosal epithelium, and how it responds to IL-33 to ...
Jing Lin +6 more
doaj +1 more source