Results 21 to 30 of about 13,720 (213)

Clinical value of soluble ST2 in cardiology

Advances in Clinical and Experimental Medicine, 2020
We are constantly looking for new parameters and markers that can help in the assessment of patients with various diseases, including cardiac disorders; this can translate into better care and improved prognosis. Suppression of tumorigenicity 2 (ST2) has recently gained interest as a potential biomarker in many fields: it is involved in many ...
Magdalena Dudek, Marta Kałużna-Oleksy, Jacek Migaj, Ewa Straburzyńska-Migaj   +3 more
openaire   +2 more sources

Soluble human Suppression of Tumorigenicity 2 is associated with endoscopic activity in patients with moderate-to-severe ulcerative colitis treated with golimumab [PDF]

, 2019
Suppressor of Tumorigenicity 2 (ST2) is an IL33 receptor detected in the mucosa and serum of ulcerative colitis (UC) patients. We evaluated soluble ST2 (sST2) as a surrogate biomarker of disease outcome and therapeutic response, in moderate-to-severe UC ...
Diogo Branquinho, Fernando Magro, Francisco Portela, Fátima Carneiro, George Philip, Gisbert JP, Helena Tavares de Sousa, Isabel Redondo, Jaime Ramos, Joana Afonso, Joanne Lopes, Kim DB, Luís Correia, Magro F, Marco Silva, Marta Patita, Marília Cravo, Patrícia Machado, Paula Lago, Paulo Caldeira, Rosa Coelho, Samuel Fernandes, Susana Lopes   +22 more
core   +3 more sources

Elevated Levels of Soluble ST2 were Associated with Rheumatoid Arthritis Disease Activity and Ameliorated Inflammation in Synovial Fibroblasts

Chinese Medical Journal, 2018
Background: Much evidence has demonstrated that interleukin (IL)-33 plays an important role in rheumatoid arthritis (RA). However, there have been limited studies about soluble ST2, a receptor for IL-33, in RA.
Lian-Jie Shi, Chen Liu, Jian-Hong Li, Xiao-Yun Zhu, Ying-Ni Li, Jiang-Tao Li   +5 more
doaj   +1 more source

Soluble ST2 levels are associated with bleeding in patients with severe Leptospirosis. [PDF]

PLoS Neglected Tropical Diseases, 2009
Severe leptospirosis features bleeding and multi-organ failure, leading to shock and death. Currently it is assumed that both exaggerated inflammation and immune suppression contribute to mortality in sepsis. Indeed, several proinflammatory cytokines are
Jiri F P Wagenaar, M Hussein Gasem, Marga G A Goris, Mariska Leeflang, Rudy A Hartskeerl, Tom van der Poll, Cornelis van 't Veer, Eric C M van Gorp   +7 more
doaj   +1 more source

Characterization of the endotheliopathy, innate-immune activation and hemostatic imbalance underlying CAR-T cell toxicities: laboratory tools for an early and differential diagnosis

Journal for ImmunoTherapy of Cancer, 2023
Background Chimeric antigen receptor (CAR)-T cell-based immunotherapy constitutes a revolutionary advance for treatment of relapsed/refractory hematological malignancies.
Alvaro Urbano-Ispizua, Sara Fernández, Pedro Castro, Francesc Fernández-Avilés, Enric Carreras, Adrián Téllez, Valentín Ortiz-Maldonado, Carlos Fernández de Larrea, Julio Delgado, Olaf Penack, Ana Belen Moreno-Castaño, Helena Ventosa, Marta Palomo, Julia Martinez-Sanchez, Alex Ramos, J M Nicolás, Gines Escolar, Maribel Diaz-Ricart   +17 more
doaj   +1 more source

Rorc restrains the potency of ST2+ regulatory T cells in ameliorating intestinal graft-versus-host disease [PDF]

, 2019
Soluble stimulation-2 (ST2) is increased during graft-versus-host disease (GVHD), while Tregs that express ST2 prevent GVHD through unknown mechanisms.
Blazar, Bruce R., Griesenauer, Brad, Hippen, Keli L., Liu, Hong, Loschi, Michael, Paczesny, Sophie, Ramadan, Abdulraouf, Reichenbach, Dawn K., Yang, Jinfeng, Zhang, Jilu   +9 more
core   +1 more source

Association of soluble ST2 with all-cause and cardiovascular mortality in renal transplant recipients: a single-centre cohort study

BMC Nephrology, 2020
Background Soluble ST2 is a novel biomarker of myocardial fibrosis with an established role in prognostication of patients with heart failure. Its role in cardiovascular risk prediction for renal transplant recipients has not been investigated despite ...
Paul A. Devine, Christopher Cardwell, Alexander P. Maxwell   +2 more
doaj   +1 more source

ST2 and Multimarker Testing in Acute Decompensated Heart Failure [PDF]

, 2015
Most data on heart failure biomarkers have been derived from patient cohorts with chronic disease. However, risk prediction in patients admitted with acute decompensated heart failure (ADHF) remains a challenge.
Antoni, Md, Bayes, Genis, DI SOMMA, Salvatore, Maisel, Alan S., Md,, Md,, Md,, Mebazaa, Alexandre   +7 more
core   +1 more source

CORELATION OF GLOBAL LONGITUDINAL STRAIN (GLS) – LEFT VENTRICLE AND SOLUBLE SUPRESSION OF TUMORGENICITY 2 (sST2) IN ACUTE HEART FAILURE WITH SYSTOLIC DYSFUNCTION

Majalah Kardiologi Indonesia, 2019
Background  :  Assessment of  left  ventricular  function  in  patients with   acute heart failure is important for prognostication, determination of treatment plan, for decisions related to  expensive device therapies and for assessing response  to ...
Herlina Yulidia, Muhammad Aminuddin, Budi S Pikir   +2 more
doaj   +1 more source

Clinical roles of soluble ST2 for the outcomes of cardiac valve operations [PDF]

Research Ideas and Outcomes, 2016
Soluble ST2 is a novel cardiac biomarker that reflects cardiac injury and the response to treatment. Previous studies showed that ST2 has less confounding and more specific than NT-proBNP. ACCF/AHA has proposed 2013 Guidelines for the Management of Heart
Robert Chen
doaj   +2 more sources