Results 191 to 200 of about 13,720 (213)
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Soluble ST2 in Ventricular Dysfunction

2015
Heart failure is a commonly encountered condition associated with increased morbidity, mortality, and healthcare cost. For years, its management has been strongly influenced by the use of B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide biomarkers. In some cases, this approach does not always identify patients with heart failure
Silvia, Lupu, Lucia, Agoston-Coldea
openaire   +2 more sources

Soluble ST2 and Galectin-3 in Heart Failure

Clinics in Laboratory Medicine, 2014
Circulating biomarkers that directly reflect disease progression, hemodynamics, and ventricular remodeling at a molecular level are critical to risk stratification in heart failure (HF), affording unique insights into pathophysiology not fully captured by traditional risk markers.
Ravi V, Shah, James L, Januzzi
openaire   +2 more sources

Soluble ST2 Serum Concentration and Renal Function in Heart Failure

Journal of Cardiac Failure, 2013
Soluble ST2 (sST2) provides important prognostic information in patients with heart failure (HF). How sST2 serum concentration is related to renal function is uncertain. We evaluated the association between sST2 and renal function and compared its prognostic value in HF patients with renal insufficiency.Patients (n = 879; median age 70.4 years; 71.8 ...
Bayes-Genis, A   +9 more
openaire   +3 more sources

Soluble ST2 and Soluble Markers of Fibrosis: Emerging Roles for Prognosis and Guiding Therapy

Current Cardiology Reports, 2020
Biomarkers of cardiac fibrosis closely track the disease state that gives rise to heart failure. The purpose of this review is to highlight recent data on the use of soluble ST2, galectin-3, and procollagen, three markers of cardiac fibrosis, for aiding with prognostication, and to explore the use of these biomarkers for guiding therapy.Soluble ST2 ...
Justin, Sharim, Lori B, Daniels
openaire   +2 more sources

Soluble ST2 as a prognostic marker in community-acquired pneumonia

Journal of Infection, 2015
Community-acquired pneumonia (CAP) is associated with high mortality when initial treatment fails. Early identification of these patients allows physicians to modify treatments earlier, increasing survival.Ninety-one hospitalized patients with CAP were studied.
Masato, Watanabe   +13 more
openaire   +2 more sources

Long-term stability of soluble ST2 in frozen plasma samples

Clinical Biochemistry, 2010
The aim of this study was to investigate the long-term in vitro stability of soluble ST2 (sST2).EDTA plasma samples were drawn from 15 individuals with various diseases. The Presage ST2 assay was used for measurement of sST2 concentrations directly after blood collection and after storing plasma samples for 18 months at -20 degrees C and -80 degrees C.
Benjamin, Dieplinger   +4 more
openaire   +2 more sources

Small Molecule ST2 Inhibitors Cause Reduction of Soluble ST2 and Improve Gvhd and Survival In Vivo

Blood, 2016
Abstract Activation of the membrane-bound Suppression of Tumorigenecity 2 (mST2) by Interleukin-33 (IL-33) in T cells leads to type-2 (Th2) and Foxp3+ regulatory (Tregs) immune responses. The mST2/IL-33 axis is not engaged when a ST2 splice isoform containing only the ST2 ectodomain and acting as a decoy receptor, called soluble ST2 ...
Chao-Yie Yang   +7 more
openaire   +1 more source

Soluble ST2 and galectin-3 in pediatric patients without heart failure

Clinical Biochemistry, 2015
Soluble ST2 (ST2) and galectin-3 (Gal3) are biomarkers of myocardial fibrosis and remodeling. This study provides a foundation for the use of ST2 and Gal3 in pediatric patients by assessing values of these biomarkers among children without heart failure.Sera from 240 children, 40 males and 40 females from each of three age groups, (2-6 years, 7-11 ...
Jeffrey W. Meeusen   +7 more
openaire   +2 more sources

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