Results 191 to 200 of about 13,720 (213)
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Soluble ST2 in Ventricular Dysfunction
2015Heart failure is a commonly encountered condition associated with increased morbidity, mortality, and healthcare cost. For years, its management has been strongly influenced by the use of B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide biomarkers. In some cases, this approach does not always identify patients with heart failure
Silvia, Lupu, Lucia, Agoston-Coldea
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Soluble ST2 and Galectin-3 in Heart Failure
Clinics in Laboratory Medicine, 2014Circulating biomarkers that directly reflect disease progression, hemodynamics, and ventricular remodeling at a molecular level are critical to risk stratification in heart failure (HF), affording unique insights into pathophysiology not fully captured by traditional risk markers.
Ravi V, Shah, James L, Januzzi
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Soluble ST2 Serum Concentration and Renal Function in Heart Failure
Journal of Cardiac Failure, 2013Soluble ST2 (sST2) provides important prognostic information in patients with heart failure (HF). How sST2 serum concentration is related to renal function is uncertain. We evaluated the association between sST2 and renal function and compared its prognostic value in HF patients with renal insufficiency.Patients (n = 879; median age 70.4 years; 71.8 ...
Bayes-Genis, A +9 more
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Soluble ST2 and Soluble Markers of Fibrosis: Emerging Roles for Prognosis and Guiding Therapy
Current Cardiology Reports, 2020Biomarkers of cardiac fibrosis closely track the disease state that gives rise to heart failure. The purpose of this review is to highlight recent data on the use of soluble ST2, galectin-3, and procollagen, three markers of cardiac fibrosis, for aiding with prognostication, and to explore the use of these biomarkers for guiding therapy.Soluble ST2 ...
Justin, Sharim, Lori B, Daniels
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Soluble ST2 as a prognostic marker in community-acquired pneumonia
Journal of Infection, 2015Community-acquired pneumonia (CAP) is associated with high mortality when initial treatment fails. Early identification of these patients allows physicians to modify treatments earlier, increasing survival.Ninety-one hospitalized patients with CAP were studied.
Masato, Watanabe +13 more
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Long-term stability of soluble ST2 in frozen plasma samples
Clinical Biochemistry, 2010The aim of this study was to investigate the long-term in vitro stability of soluble ST2 (sST2).EDTA plasma samples were drawn from 15 individuals with various diseases. The Presage ST2 assay was used for measurement of sST2 concentrations directly after blood collection and after storing plasma samples for 18 months at -20 degrees C and -80 degrees C.
Benjamin, Dieplinger +4 more
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Small Molecule ST2 Inhibitors Cause Reduction of Soluble ST2 and Improve Gvhd and Survival In Vivo
Blood, 2016Abstract Activation of the membrane-bound Suppression of Tumorigenecity 2 (mST2) by Interleukin-33 (IL-33) in T cells leads to type-2 (Th2) and Foxp3+ regulatory (Tregs) immune responses. The mST2/IL-33 axis is not engaged when a ST2 splice isoform containing only the ST2 ectodomain and acting as a decoy receptor, called soluble ST2 ...
Chao-Yie Yang +7 more
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Soluble ST2 and galectin-3 in pediatric patients without heart failure
Clinical Biochemistry, 2015Soluble ST2 (ST2) and galectin-3 (Gal3) are biomarkers of myocardial fibrosis and remodeling. This study provides a foundation for the use of ST2 and Gal3 in pediatric patients by assessing values of these biomarkers among children without heart failure.Sera from 240 children, 40 males and 40 females from each of three age groups, (2-6 years, 7-11 ...
Jeffrey W. Meeusen +7 more
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Is Soluble ST2 a Novel Biomarker of Intracerebral Hemorrhage?
Neurology, 2023Nadareishvili, Zurab +1 more
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„Soluble ST2“ – neuer Biomarker der akuten Aortendissektion?
Der Kardiologe, 2018openaire +1 more source

