Results 51 to 60 of about 6,809 (170)

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

INTERLEUKINE-33 AND SOLUBLE ST2 AND THEIR CORRELATION WITH ASTHMA SEVERITY AND AS FUTURE THERAPEUTIC TARGETS. [PDF]

Zagazig University Medical Journal, 2014
Interleukin-33 is a member of IL-1 family of cytokines and binds to two receptors: ST2 (IL-1-R1) and IL-1 receptor accessory protein (IL-1RAP). There are Two isoforms of ST2 proteins: ST2L which is a transmembrane form and a soluble ST2 (sST2) which is a
Ensaf Azazi, Ashraf El-shora, Enas Tantawy, Marwa Elsayd   +3 more
doaj   +1 more source

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source

Soluble ST2 – a new biomarker in heart failure

Cardiovascular Medicine, 2019
This article summarises insights and discussion points from the first meeting of the Swiss working group on cardiovascular bio­markers.
Patric Biaggi, Camille Ammann, Mauro Imperiali, Angelika Hammerer-Lercher, Tobias Breidthardt, Christian Müller, Alan Maisel, Frank Ruschitzka   +7 more
openaire   +1 more source

Soluble ST2, a modulator of the inflammatory response, in preterm and term labor [PDF]

The Journal of Maternal-Fetal & Neonatal Medicine, 2013
Intra-amniotic infection/inflammation (IAI) is causally linked with spontaneous preterm labor and delivery. The ST2L receptor and its soluble form (sST2) are capable of binding to interleukin (IL)-33, a member of the IL-1 superfamily. Members of this cytokine family have been implicated in the onset of spontaneous preterm labor in the context of ...
T. Stampalija, T. Chaiworapongsa, R. Romero, A.L. Tarca, G. Bhatti, P.J. Chiang, N.G. Than, E. Ferrazzi, S.S. Hassan, L. Yeo   +9 more
openaire   +3 more sources

Regulation of interleukin 33/ST2 signaling of human corneal epithelium in allergic diseases

International Journal of Ophthalmology, 2013
AIM: To identify the function of ST2 and explore the role of IL-33/ST2 signaling in regulating the pro-allergic cytokine production in human corneal epithelial cells (HCECs).METHODS: Human corneal tissues and cultured primary HCECs were treated with IL ...
Jing Lin
doaj   +1 more source

Association of IL1R1 Coding Variant With Plasma-Level Soluble ST2 and Risk of Aortic Dissection

Frontiers in Cardiovascular Medicine, 2021
Objective: Aortic dissection (AD) is characterized by an acute onset, rapid progress, and high mortality. Levels of soluble ST2 (sST2) on presentation are elevated in patients with acute AD, which can be used to discriminate AD patients from patients ...
Wenxi Jiang, Wenxi Jiang, Xue Wang, Xue Wang, Pei Gao, Fengjuan Li, Fengjuan Li, Ke Lu, Xin Tan, Xin Tan, Shuai Zheng, Shuai Zheng, Wang Pei, Wang Pei, Meiyu An, Meiyu An, Xi Li, Rong Hu, Yongliang Zhong, Junming Zhu, Jie Du, Jie Du, Yuan Wang, Yuan Wang   +23 more
doaj   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

Seminal Biomarkers and Sperm Proteomic Signatures Differentiate Acute and Chronic Male Accessory Gland Inflammation

Andrology, EarlyView.
ABSTRACT Background Male accessory gland inflammation (MAGI) comprises a heterogeneous group of inflammatory conditions that may differentially affect the seminal microenvironment and sperm function. However, whether transrectal ultrasound (TRUS)‐defined MAGI phenotypes correspond to distinct biological profiles remains insufficiently characterized ...
Emanuela Teveroni, Fiorella Di Nicuolo, Giorgia Mazzuccato, Alessandro Oliva, Emanuele Pierpaolo Vodola, Francesca Mancini, Carla Di Nardo, Edoardo Vergani, Michela Cicchinelli, Federica Iavarone, Cassandra Serantoni, Giuseppe Maulucci, Alessia Riente, Alfredo Pontecorvi, Andrea Urbani, Domenico Milardi, Silvia Baroni   +16 more
wiley   +1 more source

Role of Soluble ST2 as a Marker for Rejection after Heart Transplant [PDF]

Korean Circulation Journal, 2016
Endomyocardial biopsy is obligatory during the first year after heart transplant (HTx) for the surveillance of acute rejection. Previous attempts using cardiac biomarkers for the detection of rejection failed to show enough evidence to substitute endomyocardial biopsy.
Lee, Ga Yeon, Choi, Jin-Oh, Ju, Eun-Seon, Lee, Yoo-Jung, Jeon, Eun-Seok   +4 more
openaire   +2 more sources