Results 71 to 80 of about 6,809 (170)
Paracrine IL-33 stimulation enhances lipopolysaccharide-mediated macrophage activation.
BackgroundIL-33, a member of the IL-1 family of cytokines, provokes Th2-type inflammation accompanied by accumulation of eosinophils through IL-33R, which consists of ST2 and IL-1RAcP. We previously demonstrated that macrophages produce IL-33 in response
Tatsukuni Ohno +16 more
doaj +1 more source
Serum soluble ST2 is associated with ER-positive breast cancer [PDF]
Abstract Background ST2, a member of the interleukin (IL)-1receptor family, regulates Th1/Th2 immune responses in autoimmune and inflammatory conditions. However, the role of ST2 signaling in tumor growth and metastasis of breast cancers has not been investigated.
Lu, Da-peng +6 more
openaire +2 more sources
Dike B Ojji,1,2 Sandrine Lecour,2 Olusoji M Adeyemi,3 Karen Sliwa2,4 1Cardiology Unit, Department of Medicine, University of Abuja Teaching Hospital, Gwagwalada, Abuja, Nigeria; 2Department of Medicine, Faculty of Health Sciences, Hatter Institute for ...
Ojji DB, Lecour S, Adeyemi OM, Sliwa K
doaj
A Novel Cardiac Bio-Marker: ST2: A Review
Cardiovascular diseases (CVD) are the major cause of death worldwide. The identification of markers able to detect the early stages of such diseases and/or their progression is fundamental in order to adopt the best actions in order to reduce the ...
Marco Matteo Ciccone +7 more
doaj +1 more source
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li +8 more
wiley +1 more source
MSCs exert anti‐inflammatory, anti‐fibrotic and regenerative effects in pulmonary fibrosis. MSC‐derived exosomes reproduce many therapeutic benefits of parental MSCs. Preconditioning and genetic modification improve MSC therapeutic performance. Current preclinical and clinical evidence supports the translational potential of MSC‐based therapies ...
Hajar Nasiri +8 more
wiley +1 more source
Allogeneic hematopoietic stem cell transplantation remains a potentially curative therapy for many hematological malignancies; however, its success is significantly limited by acute graft‐versus‐host disease (aGVHD), a leading cause of post‐transplant morbidity and mortality in which endothelial dysfunction plays a central role.
Katarina Klinar, Helena Podgornik
wiley +1 more source
Objective To investigate the effects of rosuvastatin on cardiac function, lipid metabolism and serum soluble ST2 and Galectin-3 concentrations in hemodialysis patients.Methods Eighty patients who underwent hemodialysis from January 2018 to January 2019 ...
XU Li +3 more
doaj
Background Over time, the chance of cure after the diagnosis of breast cancer has been increasing, as a consequence of earlier diagnosis, improved diagnostic procedures and more effective treatment options.
Pierre Frères +11 more
doaj +1 more source
Sequence of Immunological Events During IgE‐Mediated Allergic Reactions to Food
ABSTRACT Food allergies (FA) represent a significant global health burden. Upon allergen re‐exposure, allergic patients exhibit a sequence of symptoms that vary in terms of affected organ systems, severity, time of onset and allergen reactivity thresholds.
N. A. Nagy +7 more
wiley +1 more source

