Results 71 to 80 of about 402 (126)

Paracrine IL-33 stimulation enhances lipopolysaccharide-mediated macrophage activation.

open access: yesPLoS ONE, 2011
BackgroundIL-33, a member of the IL-1 family of cytokines, provokes Th2-type inflammation accompanied by accumulation of eosinophils through IL-33R, which consists of ST2 and IL-1RAcP. We previously demonstrated that macrophages produce IL-33 in response
Tatsukuni Ohno   +16 more
doaj   +1 more source

Secretome and Pathway Analysis of Stress Induced Disc Degeneration In Vitro

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Integrated secretome and phosphoprotein profiling of human nucleus pulposus cells revealed that IL‐1β and TLR2/6 activation induce a shared degenerative program, defined by consistent upregulation of IL‐6, IL‐8, GRO‐α, ICAM‐1, and MMP‐7 and convergence on NF‐κB/AP‐1 signaling.
Exarchos Kanelis   +4 more
wiley   +1 more source

Soluble ST2 – biomarker for prognosis and monitoring in decompensated heart failure

open access: yesKardiologiia, 2019
The review aims to appraise the value of determining the concentrations of the new biomarker sST2 for assessing prognosis and monitoring treatment effectiveness of patients with decompensated heart failure during an episode of decompensation and during long-term follow-up after discharge from the hospital.
A A, Skvortsov   +2 more
openaire   +3 more sources

Potential Biomarkers for Disease Stratification and Prognosis Prediction in Pediatric Asthma: LCN2, sST2 and FGF21

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 6, June 2026.
ABSTRACT Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers.
Xu Yang   +5 more
wiley   +1 more source

The effects of rosuvastatin on cardiac function and serum soluble ST2 and Galectin-3 concentrations in hemodialysis patients

open access: yesLinchuang shenzangbing zazhi, 2019
Objective To investigate the effects of rosuvastatin on cardiac function, lipid metabolism and serum soluble ST2 and Galectin-3 concentrations in hemodialysis patients.Methods Eighty patients who underwent hemodialysis from January 2018 to January 2019 ...
XU Li   +3 more
doaj  

Variations of circulating cardiac biomarkers during and after anthracycline-containing chemotherapy in breast cancer patients

open access: yesBMC Cancer, 2018
Background Over time, the chance of cure after the diagnosis of breast cancer has been increasing, as a consequence of earlier diagnosis, improved diagnostic procedures and more effective treatment options.
Pierre Frères   +11 more
doaj   +1 more source

Serum levels of Interleukin-33 and its soluble receptor ST2 in asthmatic patients

open access: yesEgyptian Journal of Chest Disease and Tuberculosis, 2014
Interleukin-33 is a member of IL-1 family of cytokines and binds to two receptors: ST2 (IL-1-R1) and IL-1 receptor accessory protein (IL-1RAP). There are two isoforms of ST2 proteins: ST2L, a transmembrane form, and a soluble ST2 (sST2), a secreted form,
Ensaf A. Azazi   +3 more
doaj   +1 more source

The soluble receptor ST2 is positively associated with occupational exposure to radiation

open access: yesInternational Journal of Radiation Biology, 2015
Purpose Radiation exposure, besides the risk of cancer, may also increase the risk of non-cancer diseases, including cardiovascular disease (CVD). This study investigates whether the soluble form of the ST2 receptor (sST2), an emerging prognostic marker in patients with CVD, can be used to monitor the CVD risk in individuals occupationally exposed to ...
Olya, Katsarska   +5 more
openaire   +2 more sources

Comparative analysis of diagnostic significance of biomarkers’ panels in cardiac recipients in the long term period after transplantation

open access: yesВестник трансплантологии и искусственных органов, 2017
Aim. To perform comparative analysis of the diagnostic efficacy of sCD40L, PDGF-BB, VEGF-A and ST2 in recipients with cardiac rejection in different periods after transplantation. Materials and methods. The study included 144 cardiac recipients aged from
O. P. Shevchenko   +7 more
doaj   +1 more source

ST2: Current status

open access: yesIndian Heart Journal, 2018
Cardiovascular diseases are leading cause of mortality and morbidity, and are responsible for 1 out of every 6 deaths in the United States.1 Cardiac remodeling is an important determinant of long term outcomes and occurrence of heart failure (HF).
Aditi Dattagupta, Sathyamurthy Immaneni
doaj   +1 more source

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