Results 1 to 10 of about 1,856,875 (191)

Soluble Urokinase Plasminogen Activator Receptor and Venous Thromboembolism in COVID‐19 [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Venous thromboembolism (VTE) contributes significantly to COVID‐19 morbidity and mortality. The urokinase receptor system is involved in the regulation of coagulation.
Shengyuan Luo, Alexi Vasbinder, Jeanne M. Du‐Fay‐de‐Lavallaz, Joanne Michelle D. Gomez, Tisha Suboc, Elizabeth Anderson, Annika Tekumulla, Husam Shadid, Hanna Berlin, Michael Pan, Tariq U. Azam, Ibrahim Khaleel, Kishan Padalia, Chelsea Meloche, Patrick O'Hayer, Tonimarie Catalan, Pennelope Blakely, Christopher Launius, Kingsley‐Michael Amadi, Rodica Pop‐Busui, Sven H. Loosen, Athanasios Chalkias, Frank Tacke, Evangelos J. Giamarellos‐Bourboulis, Izzet Altintas, Jesper Eugen‐Olsen, Kim A. Williams, Annabelle Santos Volgman, Jochen Reiser, Salim S. Hayek   +29 more
doaj   +6 more sources

Soluble urokinase plasminogen activator receptor – What are the clinical potentials in psychiatry? [PDF]

Brain, Behavior, & Immunity - Health
Background: Mental disorders have been associated with systemic chronic inflammation, and conditions such as depression and schizophrenia are increasingly linked to inflammatory processes.
Franziska Grundtvig Huber, Milo Wolfgang Pilgaard Kristensen, Mette Ødegaard Nielsen, Torkel Vang, Jimmi Nielsen   +4 more
doaj   +4 more sources

Soluble Urokinase Plasminogen Activator Receptor Measurements: Influence of Sample Handling [PDF]

The International Journal of Biological Markers, 2001
Aim The influence of sample handling on soluble urokinase plasminogen activator receptor (suPAR) concentrations in serum and EDTA plasma was studied in 16 healthy premenopausal women.
R. Riisbro, I.J. Christensen, C. Høgdall, N. Brünner, E. Høgdall   +4 more
doaj   +4 more sources

Soluble urokinase plasminogen activator receptor and perioperative complications: a systematic review [PDF]

BMC Anesthesiology
Background Better informative predictive tools are required to improve risk-stratification in patients undergoing surgery. Soluble urokinase-type plasminogen activator receptor (suPAR) has the potential to predict postoperative complications. The primary
Ata B. Gungor, Prateek Pennathur, Hamza S. Guran, William Chu, Pavel S. Roshanov   +4 more
doaj   +5 more sources

Soluble urokinase plasminogen activator receptor is a prognostic biomarker in decompensated cirrhosis [PDF]

JHEP Reports
Background & Aims: Cirrhosis poses a significant healthcare burden, with decompensation and acute-on-chronic liver failure (ACLF) resulting in high morbidity and mortality. Reliable biomarkers of disease progression are urgently needed.
Sven Lamatsch, Mohsin Hassan, Kai Kappert, Hilmar Berger, Qingquan Bai, Zhengyang Zhao, Nirbaanjot Walia, Carlos De La Peña-Ramirez, Raphael Mohr, Münevver Demir, Juan Wang, Fabian Artusa, Richard Sittner, Fausto Andreola, Rhea Veelken, Florian van Boemmel, Jonas Schumacher, Niklas Aehling, Janett Fischer, Rajeshwar Mookerjee, Tianhui Hu, Thomas Berg, Rajiv Jalan, Frank Tacke, Pavitra Kumar, Cornelius Engelmann   +25 more
doaj   +5 more sources

Soluble urokinase plasminogen activator receptor and cardiotoxicity in doxorubicin-treated breast cancer patients: a prospective exploratory study [PDF]

Cardio-Oncology
Background Soluble urokinase plasminogen activator receptor is an inflammatory biomarker that may prognosticate cardiovascular outcomes. We sought to determine the associations between soluble urokinase plasminogen activator receptor and established ...
Jian Chu, Lillian Tung, Issam Atallah, Changli Wei, Melody Cobleigh, Ruta Rao, Steven B. Feinstein, Lydia Usha, Kathrin Banach, Jochen Reiser, Tochukwu M. Okwuosa   +10 more
doaj   +3 more sources

Soluble urokinase plasminogen activator receptor and outcomes in HFpEF: A TOPCAT ancillary study [PDF]

ESC Heart Failure
Aims Inflammation is postulated to be a key pathogenic mechanism in heart failure with preserved ejection fraction (HFpEF). Soluble urokinase plasminogen activator receptor (suPAR), a regulator of innate immune activity, is associated with incident heart
Christina G. Hutten, Annika Tekumulla, Anis Ismail, Alexi Vasbinder, Theresa Farhat, Pennelope Kunkle, Sascha N. Goonewardena, Ahmed Abdel‐Latif, Bertram Pitt, Salim S. Hayek   +9 more
doaj   +4 more sources

Proteomics-Based Soluble Urokinase Plasminogen Activator Receptor Levels Are Associated With Incident Heart Failure Risk [PDF]

JACC: Advances
Background: Higher soluble urokinase plasminogen activator receptor (suPAR) levels are associated with adverse outcomes in chronic heart failure (HF). Objectives: The authors assessed the association between proteomics-based suPAR levels and incident HF ...
Adithya K. Yadalam, MD, MSc, Matthew E. Gold, MD, Krishan J. Patel, MD, Chang Liu, PhD, MPH, Alexander C. Razavi, MD, MPH, PhD, Vardhmaan Jain, MD, Nishant Vatsa, MD, Daniel Gold, MD, Muhammad Owais, MBBS, Nisreen Haroun, MD, Yan V. Sun, PhD, Arshed A. Quyyumi, MD   +11 more
doaj   +4 more sources

Evaluation of Urokinase Plasminogen Activator Receptor, Soluble Urokinase Plasminogen Activator Receptor, and β1 Integrin in Patients with Hodgkin′s Lymphoma

Advanced Biomedical Research, 2017
Background: The objective of this study is to indicate the role of urokinase plasminogen activator receptor (uPAR), soluble uPAR (suPAR), and β1 integrin in tumor growth and invasion of lymph nodes from Hodgkin's lymphoma (HL) patients.
Shirin Kouhpayeh, Alireza Andalib, Marjan Gharagozloo, Mohammad Hossein Sanei, Nafiseh Esmaeil, Mohammad Reza Maracy   +5 more
doaj   +3 more sources

Soluble Urokinase Plasminogen Activator Receptor [PDF]

Stroke, 2014
Background and Purpose— Recent studies indicate that the urokinase system could have an important role in atherogenesis and plaque rupture. The relationships among the soluble urokinase plasminogen activator receptor (suPAR), carotid plaque, and incidence of ischemic stroke and coronary artery disease (CAD) events were studied ...
Margaretha, Persson, Gerd, Östling, Gustav, Smith, Viktor, Hamrefors, Olle, Melander, Bo, Hedblad, Gunnar, Engström   +6 more
core   +4 more sources