Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Sustainable Urban Drainage Systems (SUDS) - More than a Drainage Solution?
Shawn G. Kennedy +3 more
openalex +1 more source
High-Order Nyström Solution of the Volume - EFIE for TE-Wave Scattering
Stephen D. Gedney Gang Liu
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
When Blue Turns the Green Off: Implications of Methylene Blue Interference in Indocyanine Green Near-Infrared Fluorescence Imaging. [PDF]
Gariboldi EM +4 more
europepmc +1 more source
STABILIZED FEM SOLUTION OF VARIABLE COEFFICIENT CONVECTION-DIFFUSION EQUATION [PDF]
S. Han Ayd{\i}n
openalex +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Exploring the new classes of optical soliton solutions with diverse structure for the (2+1)-dimensional paraxial equation in fiber optics via two analytical methods. [PDF]
Ibrahim IS +6 more
europepmc +1 more source
GNSI Decision Brief: Beyond Intervention: Sustainable Solutions for Haiti’s Security Needs [PDF]
Heather Ward, Sarah Brown
openalex +1 more source

