Results 91 to 100 of about 608,220 (356)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Transmission of mitochondrial DNA following assisted reproduction and nuclear transfer [PDF]
Review of the articleMitochondria are the organelles responsible for producing the majority of a cell's ATP and also play an essential role in gamete maturation and embryo development.
Alam +200 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Viability of fibroblasts from "Curraleiro Pé Duro" cattle after different cryopreservation protocols
W.B.M. Pacheco +9 more
doaj +1 more source
The characteristics of immune factors in somatic cells from lactating dairy cows and their association with commensal bacteria in normal milk have not been clarified.
Ohtsuka Hiromichi +5 more
doaj +1 more source
Negative Cell Cycle Regulation and DNA Damage-inducible Phosphorylation of the BRCT Protein 53BP1 [PDF]
In a screen designed to discover suppressors of mitotic catastrophe, we identified the Xenopus ortholog of 53BP1 (X53BP1), a BRCT protein previously identified in humans through its ability to bind the p53 tumor suppressor.
Carpenter, Phillip B. +3 more
core
Stem-Like Adaptive Aneuploidy and Cancer Quasispecies [PDF]
We analyze and reinterpret experimental evidence from the literature to argue for an ability of tumor cells to self-regulate their aneuploidy rate. We conjecture that this ability is mediated by a diversification factor that exploits molecular mechanisms
Napoletani, Domenico +2 more
core +4 more sources
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
РАЗПРОСТРАНЕНИЕ И ДИАГНОСТИКА НА СУБКЛИНИЧНИТЕ МАСТИТИ ПРИ КОЗИТЕ В НАЧАЛОТО НА ЛАКТАЦИОННИЯ ПЕРИОД
The purpose of this study was to investigate the effectiveness of direct and indirect methods for diagnosis of subclinical mastitis in goats and prevalence of the disease in early lactation.
КАЛИН ХРИСТОВ +3 more
doaj
The ultrastructure and distribution of gonial and somatic cells in the ovary of Dermatobia hominis was studied during the 3rd larval instar. In larvae weighing between 400 and 500 mg, the ovary is partially divided into basal and apical regions by oblong
E. A. Gregorio +3 more
doaj +1 more source

