Results 91 to 100 of about 608,220 (356)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Transmission of mitochondrial DNA following assisted reproduction and nuclear transfer [PDF]

open access: yes, 2006
Review of the articleMitochondria are the organelles responsible for producing the majority of a cell's ATP and also play an essential role in gamete maturation and embryo development.
Alam   +200 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Viability of fibroblasts from "Curraleiro Pé Duro" cattle after different cryopreservation protocols

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2022
W.B.M. Pacheco   +9 more
doaj   +1 more source

Relationship between mRNA of immune factors expressed by milk somatic cells and bacteria present in healthy lactating Holstein cows

open access: yesJournal of Veterinary Research, 2019
The characteristics of immune factors in somatic cells from lactating dairy cows and their association with commensal bacteria in normal milk have not been clarified.
Ohtsuka Hiromichi   +5 more
doaj   +1 more source

Negative Cell Cycle Regulation and DNA Damage-inducible Phosphorylation of the BRCT Protein 53BP1 [PDF]

open access: yes, 2001
In a screen designed to discover suppressors of mitotic catastrophe, we identified the Xenopus ortholog of 53BP1 (X53BP1), a BRCT protein previously identified in humans through its ability to bind the p53 tumor suppressor.
Carpenter, Phillip B.   +3 more
core  

Stem-Like Adaptive Aneuploidy and Cancer Quasispecies [PDF]

open access: yes, 2013
We analyze and reinterpret experimental evidence from the literature to argue for an ability of tumor cells to self-regulate their aneuploidy rate. We conjecture that this ability is mediated by a diversification factor that exploits molecular mechanisms
Napoletani, Domenico   +2 more
core   +4 more sources

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

РАЗПРОСТРАНЕНИЕ И ДИАГНОСТИКА НА СУБКЛИНИЧНИТЕ МАСТИТИ ПРИ КОЗИТЕ В НАЧАЛОТО НА ЛАКТАЦИОННИЯ ПЕРИОД

open access: yesЖивотновъдни науки, 2014
The purpose of this study was to investigate the effectiveness of direct and indirect methods for diagnosis of subclinical mastitis in goats and prevalence of the disease in early lactation.
КАЛИН ХРИСТОВ   +3 more
doaj  

Ultrastructure of the ovary of Dermatobia hominis (Diptera: cuterebridae). I. Development during the 3rd larval instar

open access: yesMemorias do Instituto Oswaldo Cruz, 1990
The ultrastructure and distribution of gonial and somatic cells in the ovary of Dermatobia hominis was studied during the 3rd larval instar. In larvae weighing between 400 and 500 mg, the ovary is partially divided into basal and apical regions by oblong
E. A. Gregorio   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy