Results 1 to 10 of about 11,197 (138)

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene.

Journal of Experimental Medicine, 1990
Patricia J Gearhart
exaly  

The molecular basis of somatic hypermutation of immunoglobulin genes

Current Opinion in Immunology, 1996
Ursula Storb
exaly  

Reevaluation of the role of DNA polymerase θ in somatic hypermutation of immunoglobulin genes

DNA Repair, 2008
Huseyin Saribasak, Masayuki Yokoi, Fumio Hanaoka   +2 more
exaly  

Immunoglobulin kappa gene repertoire and somatic hypermutation patterns in follicular lymphoma

Blood Cells, Molecules, and Diseases, 2008
Tatjana Smilevska, Vasilis Bikos, Niki Stavroyianni   +2 more
exaly  

Control of gene conversion and somatic hypermutation by immunoglobulin promoter and enhancer sequences

Journal of Experimental Medicine, 2006
David G Schatz, Schatz David G
exaly  

Models of Somatic Hypermutation Targeting and Substitution Based on Synonymous Mutations from High-Throughput Immunoglobulin Sequencing Data

Frontiers in Immunology, 2013
Gur Yaari, Jason A Vander Heiden, Mohamed Uduman   +2 more
exaly  

Mapping the upstream boundary of somatic mutations in rearranged immunoglobulin transgenes and endogenous genes

Molecular Immunology, 1994
exaly  

Targets of somatic hypermutation within immunoglobulin light chain genes in zebrafish

Immunology, 2011
exaly  

Modulation of Pleurodeles waltl DNA polymerase mu expression by extreme conditions encountered during spaceflight. [PDF]

PLoS ONE, 2013
DNA polymerase µ is involved in DNA repair, V(D)J recombination and likely somatic hypermutation of immunoglobulin genes. Our previous studies demonstrated that spaceflight conditions affect immunoglobulin gene expression and somatic hypermutation ...
Véronique Schenten, Nathan Guéguinou, Sarah Baatout, Jean-Pol Frippiat   +3 more
doaj   +1 more source

Rapid Hypermutation B Cell Trajectory Recruits Previously Primed B Cells Upon Third SARS-Cov-2 mRNA Vaccination

Frontiers in Immunology, 2022
The COVID-19 pandemic shows that vaccination strategies building on an ancestral viral strain need to be optimized for the control of potentially emerging viral variants.
Lisa Paschold, Bianca Klee, Cornelia Gottschick, Edith Willscher, Sophie Diexer, Christoph Schultheiß, Donjete Simnica, Daniel Sedding, Matthias Girndt, Michael Gekle, Rafael Mikolajczyk, Mascha Binder   +11 more
doaj   +1 more source