Results 151 to 160 of about 280,773 (255)

Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells

Nature Methods, 2016
Gaelen T. Hess, L. Frésard, K. Han, Cameron H. Lee, Amy Li, Karlene A. Cimprich, S. Montgomery, M. Bassik   +7 more
semanticscholar   +1 more source

Dissecting the impact of somatic hypermutation on SARS-CoV-2 neutralization and viral escape

, 2023
Korenkov M, Zehner M, Cohen-Dvashi H, Borenstein-Katz A, Kottege L, Janicki H, Vanshylla K, Weber T, Gruell H, Koch M, Diskin R, Kreer C, Klein F.   +12 more
europepmc   +1 more source

Position-Dependent Differential Targeting of Somatic Hypermutation. [PDF]

J Immunol, 2020
Zhou JQ, Kleinstein SH.
europepmc   +1 more source

Sex-Biased Aging Effects on Ig Somatic Hypermutation Targeting. [PDF]

J Immunol, 2021
Cui A, Chawla DG, Kleinstein SH.
europepmc   +1 more source

Immunoglobulin VH gene diversity and somatic hypermutation during SIV infection of rhesus macaques

, 2015
Kejun Guo, Kalani Halemano, Kimberly Schmitt, Miki Katuwal, Yaqiong Wang, Michael S. Harper, Karl J. Heilman, Takeo Kuwata, Edward B. Stephens, Mario L. Santiago   +9 more
openalex   +1 more source

Clonal Characterization and Somatic Hypermutation Assessment by Next-Generation Sequencing in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: A Detailed Description of the Technical Performance, Clinical Utility, and Platform Comparison. [PDF]

J Mol Diagn, 2023
Petrova-Drus K, Syed M, Yu W, Hutt K, Zlotnicki AM, Huang Y, Kamalska-Cyganik M, Maciag L, Wang M, Ma YG, Ho C, Moung C, Yao J, Nafa K, Baik J, Vanderbilt CM, Benhamida JK, Liu Y, Zhu M, Durham B, Ewalt MD, Salazar P, Rijo I, Baldi T, Mato A, Roeker LE, Roshal M, Dogan A, Arcila ME.   +28 more
europepmc   +1 more source

"First AID" for T cell adoptive transfer: TCR affinity maturation by somatic hypermutation.

, 2013
Yosi Gozlan, Alteber Zoya, Azulay Meir, Sharbi Yunger Adi, Esther Tzehoval, Lea Eisenbach   +5 more
openalex   +1 more source

Role of Dot1L and H3K79 methylation in regulating somatic hypermutation of immunoglobulin genes. [PDF]

Proc Natl Acad Sci U S A, 2021
Duan Z, Baughn LB, Wang X, Zhang Y, Gupta V, MacCarthy T, Scharff MD, Yu G.   +7 more
europepmc   +1 more source

Somatic hypermutation shapes the viral escape profile of SARS-CoV-2 neutralising antibodies. [PDF]

EBioMedicine
Bruhn M, Obara M, Gonzalez-Hernandez M, Reineking W, Salam A, Mirolo M, Hinrichs I, Mergani A, Bartsch Y, Schambach A, Zimmer G, Baumgärtner W, Osterhaus ADME, Kalinke U.   +13 more
europepmc   +1 more source

The mRNA tether model for activation-induced deaminase and its relevance for Ig somatic hypermutation and class switch recombination. [PDF]

DNA Repair (Amst), 2022
Liu D, Goodman MF, Pham P, Yu K, Hsieh CL, Lieber MR.   +5 more
europepmc   +1 more source