Results 21 to 30 of about 13,712 (280)

Reproductive, clinical and biological markers of perimenopause

open access: yesРепродуктивная эндокринология, 2018
The problems of aging women both in the world and in our country are becoming increasingly relevant. The sharp increase in the incidence among women of the age category, which coincides with the age of menopause, is a serious argument for considering ...
О. О. Єфіменко   +2 more
doaj   +1 more source

Astragalus polysaccharide ameliorates insulin resistance in HepG2 cells through activating the STAT5/IGF‐1 pathway

open access: yesImmunity, Inflammation and Disease, Volume 11, Issue 11, November 2023., 2023
Abstract Background Insulin resistance (IR) is considered as a major factor initiating type 2 diabetes mellitus and can lead to a reduction in glucose uptake that mainly occurs in the liver. Astragalus polysaccharide (APC), extracted from the traditional Chinese medicine, has been recorded to suppress IR.
Xinxin Yue, Wei Hao, Min Wang, Yang Fu
wiley   +1 more source

SIOP PODC–adapted treatment guidelines for craniopharyngioma in low‐ and middle‐income settings

open access: yesPediatric Blood &Cancer, Volume 70, Issue 11, November 2023., 2023
Abstract Pediatric craniopharyngioma is a rare tumor with excellent survival but significant long‐term morbidities due to the loco‐regional tumor growth or secondary to its treatment. Visual impairment, panhypopituitarism, hypothalamic damage, and behavioral changes are among the main challenges.
Nisreen Amayiri   +22 more
wiley   +1 more source

The Sequence and a Three-Dimensional Structural Analysis Reveal Substrate Specificity among Snake Venom Phosphodiesterases

open access: yesToxins, 2019
(1) Background. Snake venom phosphodiesterases (SVPDEs) are among the least studied venom enzymes. In envenomation, they display various pathological effects, including induction of hypotension, inhibition of platelet aggregation, edema, and paralysis ...
Anwar Ullah   +4 more
doaj   +1 more source

Thyroxine-binding globulin: investigation of microheterogeneity [PDF]

open access: yes, 1981
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland   +4 more
core   +1 more source

Endocortical Trabecularization in Acromegaly: The Cause for the Paradoxically Increased Vertebral Fracture Risk?

open access: yesJBMR Plus, Volume 7, Issue 10, October 2023., 2023
Normalization of disease activity was followed by an increase in BMD in lumbar spine (L1–L4) without changes in TBS, but a marked decrease in CBT in Femoral Neck and Calcar Region. These data imply endocortical trabecularization that could be linked to the high incidence of vertebral fractures following treatment of acromegaly. ABSTRACT Growth hormone (
Ansgar Heck   +6 more
wiley   +1 more source

Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1984
We have validated a method for extracting and measuring the tissue content of somatomedin C (Sm-C)/insulin-like growth factor I (IGF-I), a growth-hormone-dependent, growth-promoting peptide. The Sm-C content of tissue extracts was strongly growth-hormone
A. D'ercole, A. Stiles, L. Underwood
semanticscholar   +1 more source

Differential Tissue Response to Growth Hormone in Mice [PDF]

open access: yes, 2018
Growth hormone (GH) has been shown to act directly on multiple tissues throughout the body. Historically, it was believed that GH acted directly in the liver and only indirectly in other tissues via insulin‐like growth hormone 1 (IGF‐1).
Banerjee, Ronadip R.   +4 more
core   +2 more sources

Insulin-Like Growth Factor (IGF)-I and -11 and IGFBinding Proteins-l, -2, and -3 in Children and Adolescents with Diabetes Mellitus: Correlation with Metabolic Control and Height Attainment. [PDF]

open access: yes, 1995
The putative effects of diabetes and metabolic control on circulating levels of insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) remain controversial.
Blum, Werner F.   +6 more
core   +1 more source

Sleep Dysfunction in Fibromyalgia and Therapeutic Approach Options [PDF]

open access: yes, 2020
Fibromyalgia, characterised by persistent pain, sleep disturbance, fatigue and cognitive dysfunction, is a central sensitivity syndrome that also involves abnormality in peripheral generators and in the hypothalamic pituitary adrenal axis.
Lawson, Kim
core   +1 more source

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