Results 31 to 40 of about 14,130 (288)

Expression of the insulin-like growth factor-II/mannose-6-phosphate receptor in multiple human tissues during fetal life and early infancy [PDF]

open access: yes, 1992
The insulin like growth factor-II/mannose-6-phosphate (IGF-II/M6P) receptor has been detected in many cells and tissues. In the rat, there is a dramatic developmental regulation of IGF-II/M6P receptor expression, the receptor being high in fetal and ...
Eisenmenger, Wolfgang   +5 more
core   +1 more source

Somatomedin C in dairy cows related to energy and protein supply and to milk production [PDF]

open access: yes, 2017
Somatomedin C and other hormones, as well as blood metabolites, were measured during the dry period and during lactation in dairy cows, given different amounts of energy and protein, to study metabolic and endocrine adaptations.
Binder, H.   +5 more
core  

The 'incidentaloma' of the pituitary gland. Is neurosurgery required? [PDF]

open access: yes, 1990
We describe a series of 18 patients with an intrasellar mass incidentally discovered by computed tomography or magnetic resonance imaging. The average size of the mass was 13 mm, with a range from 5 to 25 mm.
Allolio, Bruno   +4 more
core   +1 more source

Differences in the Expression of Insulin‐Like Growth Factor Signaling Pathway Members in Patients With Psoriasis Vulgaris and Controls

open access: yesMediators of Inflammation, Volume 2026, Issue 1, 2026.
Insulin‐like growth factors (IGFs) and IGF–binding proteins (IGFBPs) regulate cell proliferation, differentiation, metabolic processes, and immune activities. Psoriasis is a systemic inflammatory disease with metabolic disorders as an important comorbidity in the pathogenesis of which members of the IGF family could also play a role.
Holmannova Drahomira   +10 more
wiley   +1 more source

Massive reduction of RyR1 in muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes scoliosis

open access: yesThe Journal of Physiology, Volume 603, Issue 22, Page 6949-6977, November 15, 2025.
Abstract figure legend Intrafusal muscles contained within muscle spindles are endowed with ryanodie receptor 1 (RyR1) calcium channels and participate in proprioceptor function. Mutations in RyR1 linked to severe RYR1‐congenital myopathies affect calcium release from both extrafusal as well as intrafusal muscles.
Alexis Ruiz   +8 more
wiley   +1 more source

The in vitro and in vivo effects of human growth hormone administration on tumor growth of rats bearing a transplantable rat pituitary tumor (7315b) [PDF]

open access: yes, 1990
The direct effects of human GH and IGF-I on PRL secretion and cell proliferation were studied on PRL secreting rat pituitary tumor 7315b cells in vitro, as well as the effects in vivo of human GH administration on body weight, IGF-I levels and tumor size
Binnerts, A. (Arjen)   +4 more
core   +1 more source

Delayed Bone Maturation and Extended Growth Phase as Distinctive Features of 17α‐Hydroxylase/17,20‐Lyase Deficiency: A Retro‐Prospective Study of a Large Patient Cohort

open access: yesClinical Endocrinology, Volume 103, Issue 3, Page 303-310, September 2025.
ABSTRACT Introduction Worldwide, combined 17‐hydroxylase/17,20‐lyase deficiency (CYP17D) is a rare form of congenital adrenal hyperplasia, but it is the second most prevalent type in Brazil. An absence of sexual differentiation and hypergonadotropic hypogonadism arise from a reduction in the usual pattern of sex steroid formation in the adrenals and ...
Rafaela Fontenele   +9 more
wiley   +1 more source

A high‐resolution data set of fatty acid‐binding protein structures. III. Unexpectedly high occurrence of wrong ligands

open access: yesActa Crystallographica Section D, Volume 81, Issue 8, Page 451-464, August 2025.
Very high‐resolution fatty acid‐binding protein structures identified a substantial number of ligands that differ strongly from their expected structure. If different ligand chemistry is a potentially overlooked problem in other, lower resolution, crystal structures of protein–ligand complexes, it has repercussions for any study using such structures ...
Andreas Ehler   +4 more
wiley   +1 more source

Bromocriptine-associated ototoxicity [PDF]

open access: yes, 2007
Three patients treated with bromocriptine for chronic hepatic encephalopathy showed audiometric evidence of bilateral sensori-neural hearing-loss. Audiometrically, the hearing improved in all three patients when the bromocriptine dosage was reduced, thus
Ballantyne, J, Lanthier, PL, Morgan, MY
core   +1 more source

2‐Octyl cyanoacrylate adjuvant use in calcaneal tendon repair: A comparative experimental study in rabbits

open access: yesJournal of Experimental Orthopaedics, Volume 12, Issue 2, April 2025.
Abstract Purpose The treatment of Achilles tendon (AT) rupture can be conservative or surgical; the latter is better indicated in high‐performance athletes. The pursuit of faster recovery and reductions in skin complications and re‐ruptures have improved the tendon repair technique and early assisted rehabilitation programs.
Rogério de Andrade Gomes   +8 more
wiley   +1 more source

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