Results 51 to 60 of about 14,130 (288)

The relationship between the concentration of insulin-like growth factor, leptin and lipid metabolism indices in the blood of dairy cows during different physiological periods

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки
Despite the evidence of the fundamental influence of the endocrine system on metabolism in ruminants, there is little literature on hormonal status. There is insufficient data on tissue hormones, particularly insulin-like growth factor and leptin.
M. R. Simonov, V. V. Vlizlo, T. О. Pundiak, B. V. Gutyj, L. G. Slivinska, I. I. Kovalchuk   +5 more
doaj   +1 more source

Scale‐Dependent Rheology of Synovial Fluid Lubricating Macromolecules

Small, Volume 20, Issue 21, May 23, 2024.
A multiscale methodology using optical tweezers is developed to examine the interactions between hyaluronic acid (HA) and proteoglycan‐4 (PRG4/lubricin), which are major lubricating biomolecules of synovial fluid in the joints. For the first time, the length scale dependent structure and rheology in solution are characterized, providing a framework for
Leonardo Martin‐Alarcon, Aleksandra Govedarica, Randy H. Ewoldt, Steven L. Bryant, Gregory D. Jay, Tannin A. Schmidt, Milana Trifkovic   +6 more
wiley   +1 more source

Proteoglycan 4 (PRG4) treatment improves skin wound healing in a porcine model

The FASEB Journal, Volume 38, Issue 6, 31 March 2024.
Proteoglycan 4 (PRG4) is commonly found in synovial fluid of the articular joint and serves as a boundary lubricant of articular cartilage. Interestingly, we show that human recombinant proteoglycan 4 (rhPRG4) improves healing of porcine full‐thickness skin injuries. rhPRG4 treatment decreases fibrosis, increases vascularization, and retains adipocytes
Nicoletta Ninkovic, Holly D. Sparks, Dragana Ponjevic, Greg Muench, Jeff A. Biernaskie, Roman J. Krawetz   +5 more
wiley   +1 more source

Guidelines on diagnostics and treatment of acromegaly (draft)

Ожирение и метаболизм
We recommend acromegaly to be ruled in all patients with characteristic changes in appearance (A3). In all patients without characteristic changes in appearance, we recommend to rule out acromegaly, if several clinical signs suspicious for acromegaly are
E. G. Przhiyalkovskaya, N. G. Mokrysheva, E. A. Troshina, G. A. Melnichenko, I. I. Dedov, M. B. Antsiferov, L. I. Astafieva, T. P. Bardymova, Zh. E. Belaya, G. R. Vagapova, S. Yu. Vorotnikova, A. Yu. Grigoriev, E. N. Grineva, L. K. Dzeranova, I. A. Ilovaiskaya, P. L. Kalinin, A. M. Lapshina, A. S. Lutsenko, E. O. Mamedova, E. I. Marova, M. A. Perepelova, E. A. Pigarova, V. S. Pronin, L. Ya. Rozhinskaya, Yu. Yu. Trunin, A. S. Shutova   +25 more
doaj   +1 more source

Comparative Study of IGFBP Properties in Toad and Rat Sera [PDF]

, 1993
The levels ofIGF-Ihave been simultaneously measured byradioimmunoassayin samples of the toadBufo arenarumand of normal male Wistar rats. In addition, the different fractions of IGF-I binding proteins (IGFBP) and their binding properties have been ...
Braziunas, D., Cortizo, Ana María, Gagliardino, J.J., Jasper, H.   +3 more
core   +2 more sources

Advances in the Use of Biologics and Biomaterials toward the Improvement of Pancreatic Islet Graft Survival in Type 1 Diabetes

Advanced NanoBiomed Research, Volume 4, Issue 3, March 2024.
Although islet transplantation has the potential to serve as a curative treatment for type 1 diabetes, there are many hurdles to achieving long‐term islet graft survival. This review discusses the recent advances in strategies to improve islet survival function using exogenous compounds and conformal coatings as a promising tool for improving islet ...
Michael Yilma Yitayew, Marina Luginina, Maryam Tabrizian   +2 more
wiley   +1 more source

The biophysical and compositional properties of human basement membranes

The FEBS Journal, Volume 291, Issue 3, Page 477-488, February 2024.
Basement membranes are exceptionally adaptable materials with both extremely stiff and highly elastic properties. This article highlights these features on a selection of human membranes and links them to compositional, biomechanical, and structural profiles down to a molecular level. The role of water in modulating these attributes is also scrutinized
Monica S. Schoenenberger, Willi Halfter, Alexia Ferrand, Kathrin Halfter, Alexandar Tzankov, Hendrik P. N. Scholl, Paul Bernhard Henrich, Christophe A. Monnier   +7 more
wiley   +1 more source

Quantification of insulin‐like growth factor‐I by liquid chromatography–mass spectrometry

Rapid Communications in Mass Spectrometry, Volume 38, Issue S1, January 2024.
We describe three methods of sample preparation for the liquid chromatography coupled with mass spectrometric measurement of insulin‐like growth factor‐I concentration in blood. One method involves trypsin digestion, the second involves intact protein quantification and the third method is a combination of the first two.
Danielle A. Moncrieffe, David A. Cowan
wiley   +1 more source

Molecular crosstalk between insulin‐like growth factors and follicle‐stimulating hormone in the regulation of granulosa cell function

Reproductive Medicine and Biology, Volume 23, Issue 1, January/December 2024.
Crosstalk between insulin‐like growth factors and follicle‐stimulating hormone in the regulation of ovarian antral follicles. Abstract Background The last phase of folliculogenesis is driven by follicle‐stimulating hormone (FSH) and locally produced insulin‐like growth factors (IGFs), both essential for forming preovulatory follicles.
Emily Hayes, Nicola Winston, Carlos Stocco   +2 more
wiley   +1 more source

Stimulation of body weight increase and epiphyseal cartilage growth by insulin like growth factor [PDF]

The ability of insulin-like growth factor (IGF) to induce growth in hypophysectomized immature rats was tested by continuous infusion of the partially purified factor at daily doses of 6, 21, and 46 mU for an 8-day period.
Ellis, S.
core   +1 more source