Somatolactogens, Somatomedins, and Immunity
Journal of Dairy Science, 1993 The neuroendocrine and immune systems participate as active partners in host homeostatic and defense mechanisms. This partnership involves a complex intercommunication system employing an array of shared ligands and receptors. Hormones of the somatolactogen family have marked influences on immune events in vivo, including the maintenance of lymphoid ...
S, Arkins, R, Dantzer, K W, Kelley
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Cushing Syndrome Associated Myopathy: It Is Time for a Change [PDF]
Endocrinology and Metabolism, 2021 Cushing syndrome is the result of excessive levels of glucocorticoids. Endogenous Cushing syndrome is rare with an incidence of two to three cases per million per year.
Martin Reincke
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Insulin-Like Growth Factors, Binding Proteins and Their Role in Pregnancy in Patients With Diabetes. [PDF]
J Diabetes ResThe insulin‐like growth factor (IGF) axis, an evolutionarily conserved system, is critical in regulating cell growth, proliferation, and survival, affecting nearly all organ systems. This axis comprises two growth factors, IGF‐I and IGF‐II, and six insulin‐like growth factor–binding proteins (IGFBPs), modulating IGF activity.
Gladych-Macioszek A +5 more
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Prognostic significance of growth hormone in pediatric liver transplantation
Вестник трансплантологии и искусственных органов, 2023 Growth hormone (GH) plays a leading role in the regulation of cell and tissue metabolism and growth. Its effects are mediated through the so-called somatomedins, among which the most important is the liver-produced insulinlike growth factor 1 (IGF-1). It
R. M. Kurabekova +8 more
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, 1985 Primary cultures of skeletal muscle satellite cells were induced to proliferate by exposure to physiologic levels of somatomedins and pharmacologic levels of insulin.
Dodson, Michael Verne
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Delayed Bone Maturation and Extended Growth Phase as Distinctive Features of 17α-Hydroxylase/17,20-Lyase Deficiency: A Retro-Prospective Study of a Large Patient Cohort. [PDF]
Clin Endocrinol (Oxf)ABSTRACT Introduction Worldwide, combined 17‐hydroxylase/17,20‐lyase deficiency (CYP17D) is a rare form of congenital adrenal hyperplasia, but it is the second most prevalent type in Brazil. An absence of sexual differentiation and hypergonadotropic hypogonadism arise from a reduction in the usual pattern of sex steroid formation in the adrenals and ...
Fontenele R +9 more
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Degradation of somatomedins by the thioredoxin system [PDF]
, 1985 The insulin disulfide reducing thioredoxin system from rE.coli was used to investigate a possible mechanism of degradation for the two somatomedins, insulin-like growth factor I and II (IGF-I and -II).
Arne Holmgren +3 more
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Insulin-like Growth Factors in a clinical setting: Review of IGF-I
Biomedical Papers, 2015 Background and Aims: Interest in growth hormone (GH) is inextricably linked to the need for in depth understanding of the somatomedins (insulin-like growth factors) which are polypeptides structurally similar to insulin and with broad physiological ...
Zdenek Frysak +3 more
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Identification and characterization of insulin-like growth factor receptors on adult rat cardiac myocytes: linkage to inositol 1,4,5-trisphosphate formation. [PDF]
, 1992 Cultured cardiac myocytes from adult Sprague-Dawley rats express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose 6-phosphate (IGF-II/Man6P) receptors and respond to IGF-I with a dose-dependent accumulation of
Berg, Ingeborg +6 more
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Associations between Maternal and Fetal Levels of Total Adiponectin, High Molecular Weight Adiponectin, Selected Somatomedins, and Birth Weight of Infants of Smoking and Non-Smoking Mothers. [PDF]
Int J Environ Res Public Health, 2020 The aim of the study was to determine the relationships between maternal smoking, total adiponectin, high molecular weight adiponectin (HMW adiponectin), selected somatomedins, and the birth weight of newborns.
Chełchowska M +5 more
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