Results 31 to 40 of about 1,398 (171)

A high‐resolution data set of fatty acid‐binding protein structures. III. Unexpectedly high occurrence of wrong ligands

Acta Crystallographica Section D, Volume 81, Issue 8, Page 451-464, August 2025.
Very high‐resolution fatty acid‐binding protein structures identified a substantial number of ligands that differ strongly from their expected structure. If different ligand chemistry is a potentially overlooked problem in other, lower resolution, crystal structures of protein–ligand complexes, it has repercussions for any study using such structures ...
Andreas Ehler, Christian Bartelmus, Joerg Benz, Inken Plitzko, Markus G. Rudolph   +4 more
wiley   +1 more source

2‐Octyl cyanoacrylate adjuvant use in calcaneal tendon repair: A comparative experimental study in rabbits

Journal of Experimental Orthopaedics, Volume 12, Issue 2, April 2025.
Abstract Purpose The treatment of Achilles tendon (AT) rupture can be conservative or surgical; the latter is better indicated in high‐performance athletes. The pursuit of faster recovery and reductions in skin complications and re‐ruptures have improved the tendon repair technique and early assisted rehabilitation programs.
Rogério de Andrade Gomes, Marco Antônio Percope de Andrade, Luiz Eduardo Moreira Teixeira, Bruno Jannotti Pádua, Sidney Max E. Silva, Matheus Maciel Vilela, Paulo Feliciano Sarquis Dias, Eduardo Paulino Júnior, Ivana Duval de Araújo   +8 more
wiley   +1 more source

Probiotics and Spirulina platensis Improved Growth Performance of Nile Tilapia (Oreochromis niloticus) by Upgrading Intestinal Morphology and Activating GH/IGF Axis

Aquaculture Research, Volume 2025, Issue 1, 2025.
Probiotics and spirulina are used to improve health, growth, and immunity of fish. The purpose of this study was to evaluate the effects of water additive probiotics and dietary Spirulina platensis on growth (weight gain (WG) and specific growth rate (SGR)), hematobiochemical parameters (hemoglobin (Hb) and blood glucose (Glu)), intestinal histology ...
Muallimul Islam, Haphsa Khanom, Naimul Islam, Fouzia Fariha, Bilal Ahamad Paray, Md Mahiuddin Zahangir, Md Shahjahan   +6 more
wiley   +1 more source

Nutritional Benefits of Lycopene and Beta‐Carotene: A Comprehensive Overview

Food Science &Nutrition, Volume 12, Issue 11, Page 8715-8741, November 2024.
This comprehensive review explores the sources, structures, physiochemical properties, absorption, metabolism, and functional advantages of lycopene and beta‐carotene, crucial carotenoid antioxidants for human health. We discuss their roles in disease prevention, including cardiovascular disease, cancer, and metabolic disorders, as well as their ...
Tabussam Tufail, Huma Bader Ul Ain, Sana Noreen, Ali Ikram, Muhammad Tayyab Arshad, Muhammed Adem Abdullahi   +5 more
wiley   +1 more source

Chondroitin sulfate in invertebrate development

Proteoglycan Research, Volume 2, Issue 4, October-December 2024.
Abstract Chondroitin sulfate (CS) is one of the most evolutionarily conserved glycosaminoglycans (GAGs). Although CS's function in skeletal development is well established in vertebrates, CS exists in more primitive animal species with no cartilage or bone, such as C.
Ayano Moriya, Eriko Nakato, Jin‐Ping Li, Hiroshi Nakato   +3 more
wiley   +1 more source

Low cholesterol levels are good markers for central hypothyroidism in case with dialysis using roxadustat

Clinical Case Reports, Volume 12, Issue 9, September 2024.
Key Clinical Message Recently, hypoxia‐inducible factor prolyl hydroxylase (HIF‐PH) inhibitors have been used for renal anemia, but side effects have also been reported. We report on the association of central hypothyroidism and cholesterol with roxadustat.
Serina Kita, Hiroshi Okuyama, Takaya Kondo, Mizuki Hayashi, Shinichiro Nakao, Toshitaka Sawamura, Keiji Fujimoto, Atsushi Nakagawa, Hitoshi Yokoyama, Kengo Furuichi   +9 more
wiley   +1 more source

Proteomic exploration of potential blood biomarkers in haemophilic arthropathy

Health Science Reports, Volume 7, Issue 9, September 2024.
Abstract Background and Aims The pathophysiology of haemophilic arthropathy (HA) is complex and largely undefined. Proteomic analyses provide insights into the intricate mechanisms of the HA. Our study aimed to identify differentially expressed proteins in relation to the severity of HA, explore their pathophysiological roles, and evaluate their ...
Nataša Kalebota, Ruđer Novak, Stela Hrkač, Porin Perić, Grgur Salai, Marko Močibob, Marija Pranjić, Zbyněk Zdráhal, Václav Pustka, Nadica Laktašić Žerjavić, Milan Milošević, Marijo Vodanović, Silva Zupančić Šalek, Lovorka Grgurević   +13 more
wiley   +1 more source

The Somatomedin Hypothesis: 2001 [PDF]

Endocrine Reviews, 2001
AbstractSince the original somatomedin hypothesis was conceived, a number of important discoveries have allowed investigators to modify the concept. Originally somatic growth was thought to be controlled by pituitary GH and mediated by circulating insulin-like growth factor-I (IGF-I, somatomedin C) expressed exclusively by the liver. With the discovery
D, Le Roith, C, Bondy, S, Yakar, J L, Liu, A, Butler   +4 more
openaire   +2 more sources

Early life interventions metformin and trodusquemine metabolically reprogram the developing mouse liver through transcriptomic alterations

Aging Cell, Volume 23, Issue 9, September 2024.
This study examined the effects of metformin (MF) and trodusquemine (MSI‐1436) on the livers of young, developing mice. We discovered that MSI‐1436 significantly alters mRNA and miRNA expression more potently than MF, impacting key metabolic pathways.
Sarah A. Ashiqueali, Augusto Schneider, Xiang Zhu, Ewelina Juszczyk, Mishfak A. M. Mansoor, Yun Zhu, Yimin Fang, Bianka M. Zanini, Driele N. Garcia, Natalie Hayslip, David Medina, Samuel McFadden, Robert Stockwell, Rong Yuan, Andrzej Bartke, Michael Zasloff, Shadab Siddiqi, Michal M. Masternak   +17 more
wiley   +1 more source

Somatomedin and growth retardation in children with chronic renal insufficiency

, 1978
A number of recent observations have brought into question a possible role for the somatomedins in explaining the growth failure which characterizes chronic renal disease in childhood [1–5].
Lewy, John E., VanWyk, Judson J.
core   +1 more source