Results 271 to 280 of about 128,394 (306)

Somatostatin

New England Journal of Medicine, 1983
Fonction de la somatostatine dans la regulation des ilots pancreatiques. La somatostatine dans la fonction gastrointestinale. La somatostatine endogene dans la pathogenese d'affections digestives. Mecanismes d'action de la somatostatine. Fonctions neurologiques. Alterations en pathologie cerebrale. Utilisation de la somatostatine en clinique.
Ghirlanda, G, UCCIOLI, LUIGI, Manna, R, Altomonte, L, BERTOLI, ALDO, Raimondo, S, Greco, A.   +6 more
  +9 more sources

Somatostatin and somatostatin analogues in oncology

Cancer Treatment Reviews, 1989
La somatostatine, et ses analogues, sa structure, sa pharmacologie, son effet antiproliferatif, et son activite anticancereux sont ...
H. Parmar, A. Bogden, B. De Rouge, R.H. Phillips, S.L. Lightman, M. Mollard   +5 more
openaire   +3 more sources

Somatostatin and Somatostatin Receptors

2009
The biological effects of somatostatin (SST) were first encountered unexpectedly in the late 1960s in two unrelated studies, one by Krulich et al. (1968) who reported on a growth hormone (GH)-releasing inhibitory substance from hypothalamic extracts, and the other, by Hellman and Lernmark (1969), on the presence of a potent insulin inhibitory factor ...
Ujendra Kumar, Michael P. Grant
openaire   +3 more sources

Somatostatin analogues: Are they analogues of somatostatin?

Journal of Endocrinological Investigation, 2002
Dear Sir, Somatostatin (SRIH) was discovered because of its surprising inhibitory effect on GH secretion (1), and thus appropriately named. Later on, its ubiquitousness and the inhibiting activity on pancreatic hormones and on other types of hormones, rendered its name too restrictive. It was by then too late to change it.
openaire   +3 more sources

Evolutionary history of the somatostatin and somatostatin receptors

Journal of Genetics, 2009
Somatostatin and its receptors have a critical role in mammalian growth through their control pattern of secretion of growth hormone, but the evolutionary history of somatostatin and somatostatin receptors are ill defined. We used comparative whole genome analysis of Danio rerio, Carassius auratus, Xenopus tropicalis, Gallus gallus, Monodelphis ...
Muhammad Moaeen-ud-Din, Muhammad Moaeen-ud-Din, Li Guo Yang   +2 more
openaire   +3 more sources

Somatostatin and Somatostatin Receptor Physiology

Endocrine, 2003
Since the discovery of somatostatin (SST) over three decades ago, its ubiquitous distribution and manifold functions are still being documented. SST is synthesized in the hypothalamus and transported to the anterior pituitary gland where it tonicaly inhibits GH and TSH secretion as well as being responsible for GH pulsatile release.
openaire   +2 more sources

Somatostatin and thyroid

Journal of Endocrinological Investigation, 2003
We discuss the recent knowledge concerning domatostatin action in follicular and parafollicular cell function regulation.
ZATELLI, Maria Chiara, ROTI E, DEGLI UBERTI, Ettore   +2 more
openaire   +3 more sources

Somatostatin analogs

The Journal of Peptide Research, 2001
Abstract:  Somatostatin is a hypothalamic peptide hormone that inhibits the secretion of growth hormone, glucagon, insulin, gastrin and secretin, and also plays a role in neural transmission. Because of its wide range of possible clinical applications hundreds of somatostatin analogs have been synthesized and bioassayed to date.
A. Janecka, M. Zubrzycka, T. Janecki
openaire   +3 more sources

Somatostatin-28, somatostatin-14 and somatostatin analogs: Effects on thermoregulation

Brain Research, 1981
Somatostatins, somatostatin-14, somatostatin-28, and desAA [D-Trp8]-somatostatin, with differential potencies, act in the brain to reverse chemical-induced hypothermia and to produce hyperthermia. Somatostatins are more potent and loger acting than prostaglandin E2 in producing hyperthermia.
N. Ling, Jean Rivier, Marvin R. Brown
openaire   +3 more sources

Somatostatin Analogs Inhibit Somatostatin Release*

Endocrinology, 1979
To determine if, like insulin, somatostatin inhibits its own secretion from the pancreas, nonimmunoreactive analogs of somatostatin were perfused in an isolated dog pancreaticoduodenal preparation using a nonrecirculating system. [D-Trp8-D-Cys14]somatostatin, at a concentration of 200 ng/ml, blocked the response of somatostatin-like immunoreactivity ...
Roger H Unger, R. E. Dobbs, Marvin R. Brown, Wylie Vale, E. Ipp, J. Rivier   +5 more
openaire   +3 more sources