Results 211 to 220 of about 57,406 (251)

Somatostatin receptor imaging

Seminars in Nuclear Medicine, 2002
[(111)In-DTPA(0)]octreotide is a radiopharmaceutical with a great potential for the visualization of somatostatin receptor-positive tumors. The overall sensitivity of Somatostatin Receptor Imaging (SRI) to localize neuroendocrine tumors is high.
Kwekkeboom, Dik, Krenning, Eric
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Somatostatins and their receptors in fish

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2001
Somatostatin (SRIF) is a multigene family of peptides. SRIF-14 is conserved with identical primary structure in species across the vertebrates. The presence of multiple SRIF genes has been demonstrated in a number of fish species. Notably, three distinct SRIF genes have been identified in goldfish. One of these genes, which encodes [Pro(2)]SRIF-14, has
X, Lin, R E, Peter
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Somatostatin and Somatostatin Receptor Physiology

Endocrine, 2003
Since the discovery of somatostatin (SST) over three decades ago, its ubiquitous distribution and manifold functions are still being documented. SST is synthesized in the hypothalamus and transported to the anterior pituitary gland where it tonicaly inhibits GH and TSH secretion as well as being responsible for GH pulsatile release.
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Somatostatin receptors in the adrenal

Molecular and Cellular Endocrinology, 1986
Somatostatin receptors have been visualized in the adrenal by autoradiography using the iodinated Tyr3 derivative of the somatostatin octapeptide analog SMS 201-995 (H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr(ol), Sandostatin*). In the rat adrenal gland somatostatin receptors are not exclusively restricted to the glomerulosa cell layer, but can also be ...
R, Maurer, J C, Reubi
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The somatostatin receptor family

Life Sciences, 1995
The diverse biological effects of somatostatin (SST) are mediated through a family of G protein coupled receptors of which 5 members have been recently identified by molecular cloning. This review focuses on the molecular biology, pharmacology, expression, and function of these receptors with particular emphasis on the human (h) homologs.
Y C, Patel, M T, Greenwood, R, Panetta, L, Demchyshyn, H, Niznik, C B, Srikant   +5 more
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Somatostatin and somatostatin receptors in the diagnosis and treatment of gliomas

Journal of Neuro-Oncology, 1997
Somatostatin analogues are in clinical use for the diagnosis and treatment of several oncological indications, namely pituitary adenomas and endocrine gastrointestinal tumors. In addition for a variety of malignancies their potential value is being studied.
K, Lamszus, W, Meyerhof, M, Westphal
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[Somatostatin and somatostatin receptors in the prostate].

Minerva endocrinologica, 2001
Somatostatin (st) exerts a role in the control of prostate growth and function acting both at hypothalamus-hypophysis level and at glandular level. St analogues have been used to control prostate cancer (CaP) in clinical trials, with contradictory results.
SINISI, Antonio Agostino, BELLASTELLA A, PASQUALI, Daniela   +2 more
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Molecular biology of somatostatin receptors

Trends in Neurosciences, 1993
The neuropeptide somatostatin (SRIF) has diverse physiological actions in the brain and endocrine organs. A family of SRIF receptors has recently been cloned that may mediate the distinct biological effects of SRIF. These receptors have a high degree of amino acid sequence similarity among themselves, but their sequences are different from any other ...
G I, Bell, T, Reisine
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[Immunity and somatostatin receptors].

Minerva endocrinologica, 2001
The presence of at least three different types of somatostatin receptors in the thymus has been demonstrated using molecular biology techniques or radioimmunological methods. In view of the chemotactical activity shown by somatostatin in other lymphopoietic regions like bone marrow, it was hypothesised that this neuropeptide might play a role in ...
PELUSO G, MANSI, Luigi
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The Somatostatin Receptor In The GI Tract

Annual Review of Physiology, 1992
Since its isolation from the hypothalamus in 1973 (10), somatostatin has been shown to occur not only in the brain, but also in almost all peripheral tissues. This ubiquitous distribution and short half-life of somatostatin in the blood suggest that this peptide could play a local regulatory role and implies the involvement of receptors distributed ...
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