Results 101 to 110 of about 37,487 (203)
The role of primary cilia and sonic hedgehog signalling in adrenal development function.
, 2012 PhDPrimary cilia are sensory organelles found on most vertebrate cells during interphase. They play key roles in development, cell signalling and cancer, and are involved in signal transduction pathways such as Hh and Wnt signalling.
Cogger, Kathryn
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The recklessness of Sonic the Hedgehog
, 2023 Sonic the Hedgehog is naturally very athletic and enjoys running at top speeds. His complete disregard for his well‑being could lead to many health problems once he is past his teenage years.
Gakhal, Gurleen
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LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain
Nature Communications, 2016 Epigenetic regulation plays a key role in cortical development. Here the authors show that Rcor2, a co-repressor of the histone demethylase LSD1/KDM1A complex, regulates neural progenitor cell proliferation and cortical neurogenesis by repressing sonic ...
Yixuan Wang +11 more
doaj +1 more source
, 2006 We show that desert hedgehog ( dhh), a signaling molecule expressed by Schwann cells, is essential for the structural and functional integrity of the peripheral nerve.
Umehara, F +6 more
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Cell migration domains in the chick telencephalon [PDF]
, 1996 Little is known about the process by which the vertebrate forebrain (the diencephalon and telencephalon) becomes regionalized during development.
Montgomery, John Michael
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Fast-tracking morphogen diffusion
, 2006 The readout of morphogen concentrations has been proposed to be an essential mechanism allowing embryos to specify cell identities (Wolpert Trends Genet 12 (1996) 359), but theoretical and experimental results have led to conflicting ideas as to how ...
Olivier Cinquin, Cinquin, O
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Sonic hedgehog regulates patterning in early embryos.
, 1996 Recently, a new family of genes, homologues of the Drosophila segment polarity gene hedgehog, has been cloned in vertebrates. One of them, Sonic hedgehog, is expressed in tissues that are known to be inductive centres for patterning early embryos ...
MARIGO, Valeria +5 more
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Genome-wide analysis of gene expression and alternative splicing in human medulloblastoma
, 2010 Medulloblastoma is a malignant embryonal tumour of the cerebellum which most commonly affects children. A subset of tumours is thought to arise from cerebellar granule cell precursors (GCPs) that fail to undergo normal neuronal development, following ...
Menghi, F.
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ProceedingsAims: Medulloblastoma (MBs), the most prevalent malignant paediatric brain tumour, exhibits distinct subgroups—Wingless (WNT), Sonic Hedgehog (SHH), Group 3 (G3), and Group 4 (G4)—and each is characterized by unique molecular signatures and clinical ...
Charley Comer +1 more
doaj +1 more source
, 2014 Due to the development of drug resistance, the outcome for the majority of patients with acute myeloid leukemia (acute myelogenous leukemia; AML) remains poor.
Lu, Frank Leigh;Yu, Ching-Chia;Chiu, Huei-Hsuan;Liu, Hsingjin Eugene;Chen, Shao-Yin;Lin, Shufan;Goh, Ting-Yi;Hsu, Hsin-Chih;Chien, Chih-Han;Wu, Han-Chung;Chen, Ming-Shan;Schuyler, Scott C.;Hsieh, Wu-Shiun;Wu, Mei-Hwan;Lu, Jean +1 more
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