Results 131 to 140 of about 66,215 (305)

The Suppression of Medulloblastoma Cell Migration Using Clinically Significant Doses of Simvastatin through Mevalonate Pathway Targeting

open access: yesProceedings
Aims: Medulloblastoma (MBs), the most prevalent malignant paediatric brain tumour, exhibits distinct subgroups—Wingless (WNT), Sonic Hedgehog (SHH), Group 3 (G3), and Group 4 (G4)—and each is characterized by unique molecular signatures and clinical ...
Charley Comer   +1 more
doaj   +1 more source

Genetic Mapping of Orofacial Traits Reveals a Single Genomic Region Associated With Differences in Multiple Parameters of Jaw Size Between Astyanax mexicanus Surface and Cavefish

open access: yesEvolution &Development, EarlyView.
By performing a genetic association study in cave × surface fish F2 hybrids, we discovered that premaxilla width, dentary length, and maxillary length are all significantly associated with a region on Chromosome 13 containing 109 genes. ABSTRACT The regulation of bone size is a poorly understood and complex developmental process.
Amanda K. Powers   +7 more
wiley   +1 more source

Coupling of Smoothened to inhibitory G proteins reduces voltage-gated K [PDF]

open access: yes, 2018
SMO (Smoothened), the central transducer of Hedgehog signaling, is coupled to heterotrimeric Gi proteins in many cell types, including cardiomyocytes.
Al-Owais, Moza   +6 more
core   +1 more source

sonic hedgehog

open access: yes
Citation: 'sonic hedgehog' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11232 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial
openaire   +1 more source

The spectrum of breast in situ papillary carcinomas with invasion and invasive breast carcinomas with papillary features: an overview of histological subtypes and diagnostic challenges

open access: yesHistopathology, EarlyView.
Invasive breast carcinomas with papillary features (IBCP) comprise diverse subtypes with variable architecture, histopathology, and clinical behaviour. This review outlines evolving classification, diagnostic criteria, and treatment implications, highlighting challenges in distinguishing in situ from invasive lesions. Standardised diagnostic approaches
Emad A Rakha   +2 more
wiley   +1 more source

Publisher's Note: Cilia-localized GID/CTLH ubiquitin ligase complex regulates protein homeostasis of sonic hedgehog signaling components

open access: green, 2022
Friederike Hantel   +10 more
openalex   +2 more sources

Sonic hedgehog is essential for proximal-distal outgrowth of the limb bud in salamanders [PDF]

open access: gold, 2021
Sruthi Purushothaman   +2 more
openalex   +1 more source

Does any fish scale of a fish have the same number of marks? A case study for two Mugilidae species

open access: yesJournal of Fish Biology, EarlyView.
Abstract This study evaluates the difference in growth marks in scales from nine body areas of two Mugilidae species from the Gulf of Mexico: Mugil curema and Mugil cephalus. It addresses whether the different body areas show more (or fewer) marks, and which area(s) would be more useful in fish biology studies relying on mark analysis.
Ebenecer Guerra   +6 more
wiley   +1 more source

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