Results 171 to 180 of about 42,109 (300)

HDL nanoparticles targeting sonic hedgehog subtype medulloblastoma

, 2018
Medulloblastoma is the most common paediatric malignant brain cancer and there is a need for new targeted therapeutic approaches to more effectively treat these malignant tumours, which can be divided into four molecular subtypes.
Jonathan B. Bell, C. Shad Thaxton, Jonathan S. Rink, Jessica Clymer, Leonidas C. Platanias, Frank Eckerdt, Stewart Goldman   +6 more
core   +1 more source

Modulation of Ciliary Phosphoinositide Content Regulates Trafficking and Sonic Hedgehog Signaling Output [PDF]

, 2015
Marcelo Chávez, Sabrina Ena, Jacqueline Van Sande, Alban de Kerchove d’Exaerde, Stéphane Schurmans, Serge N. Schiffmann   +5 more
openalex   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Sonic Hedgehog, un morphogène en quête de fonction dans le cerveau adulte [PDF]

, 2011
Martial Ruat, Élodie Angot, Élisabeth Traiffort   +2 more
openalex   +1 more source

Gene expression dynamic analysis reveals co-activation of Sonic Hedgehog and epidermal growth factor followed by dynamic silencing [PDF]

, 2020
Vahed Maroufy, Pankil Shah, Arvand Asghari, Nan Deng, Rosemarie N.U. Le, Juan Camilo Ramírez, Ashraf Yaseen, W. Jim Zheng, Michihisa Umetani, Hulin Wu   +9 more
openalex   +1 more source

Genomic Contributors to Congenital Diaphragmatic Hernia: Results of Exome Sequencing in 560 Probands and Cross Reference of Findings in an Independent Cohort

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1821-1831, August 2026.
ABSTRACT There is a strong genetic contribution to the etiology of congenital diaphragmatic hernia (CDH). This study evaluated genetic testing results and diagnostic yield for fetuses and children with CDH. This was a retrospective cohort study of exome sequencing (ES) performed at GeneDx for fetuses and children ≤ 18 years of age with CDH compared ...
Justin Blair, Kevin Carratu, Natalie E. Rintoul, Holly L. Hedrick, William H. Peranteau, Catherine M. Avitabile, Kirsty McWalter, Paul Kruszka, Ian D. Krantz, K. Taylor Wild   +9 more
wiley   +1 more source

Cyclopamine targeting of sonic hedgehog may eradicate therapy-resistant brain tumor stem cells [PDF]

, 2007

openalex   +1 more source

Sphingosine‐1‐Phosphate Receptor 1 Regulates Competition Dependent Astrocyte Morphogenesis and Tiling in Murine Cortex

Glia, Volume 74, Issue 8, August 2026.
Neuronal contact‐induced expression of S1PR1 in astrocytes is regulated by JAK‐STAT3 signaling. Astrocytic S1PR1 modulates cortical astrocyte morphogenesis. Astrocytic S1PR1 regulates astrocyte territorial overlap/tiling in a competition dependent manner.
Jean Patrick M. Gonzales, Connor Tuck, Surya Chandra Rao Thumu, Soha Munir, Jaden Harris, Hunain (Zeik) Tariq, Paul Marcelli, Oscar Dominguez, Kaviya Suriyakumar Anbazagan, Sandeep K. Singh   +9 more
wiley   +1 more source

Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb.

, 1996
Hedgehog genes have been implicated in inductive signaling during development in a variety of organisms. A key element of the hedgehog signaling system is encoded by the gene patched.
MARIGO, Valeria, TABIN C. J., GOODRICH L. V., SCOTT M. P., JOHNSON R. L.   +4 more
core  

Downstream effects of Sonic hedgehog on glis3 and insulin expression

, 2022
Sonic hedgehog is known to play both permissive and restrictive roles during the formation of the pancreas in zebrafish. Glis3 is a transcription factor that has been implicated in the specification of insulin producing cells within the pancreas during ...
Shroat, Delaney
core