Results 181 to 190 of about 61,899 (269)

Blood–Brain Barrier: Structure, Function, Diseases, and Drug Delivery Systems

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract illustrates how blood–brain barrier‐targeted nanomedicine integrates diverse nanocarrier platforms with mechanism‐based therapeutic strategies to overcome delivery barriers in ischemic stroke, enabling targeted modulation of oxidative stress, inflammation, excitotoxicity, and neuronal survival.
Yanan He, Mengyao Qu, Lu Yu, Lipeng He, Yixun Lu, Jin Hong, Miao Sun, Huikai Yang, Weidong Mi, Hang Guo, Yulong Ma   +10 more
wiley   +1 more source

Gedunin Impacts Pancreatic Cancer Stem Cells Through the Sonic Hedgehog Signaling Pathway. [PDF]

Pharmaceuticals (Basel)
Perez K, Rodriguez S, Barragan J, Narayanan P, Ruiseco A, Rajkumar P, Ramirez N, Vasquez V, Lakshmanaswamy R, Subramani R.   +9 more
europepmc   +1 more source

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, Volume 40, Issue 4, Page 2003-2024, April 2026.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

CMKLR1/PKA signaling reinforces sonic hedgehog pathway to promote medulloblastoma pathogenesis. [PDF]

Oncogenesis
Wang S, Jiang T, Wang T, Yang Z, Wang T, Zhang X, Gou X, Jia L, Wang L, Song Y.   +9 more
europepmc   +1 more source

Managing Skin Side Effects Associated With Oncology Treatments: Asian Perspective on Use of Dermocosmetics

Asia-Pacific Journal of Clinical Oncology, Volume 22, Issue 2, Page 186-198, April 2026.
Skin adverse events (AEs) frequently accompany all types of anticancer treatments. This publication discusses how recent international guidance on best‐practices use of dermocosmetics can be adapted to the North Asia region (China, Hong Kong, Japan, Republic of Korea, and Taiwan).
Meng Pan, Jianguo Sun, Makoto Kawashima, You Chan Kim, Mison Chun, Chia‐Yu Chu, Yi‐Hsin Liang, Mee Chang, Delphine Kerob, Brigitte Dreno   +9 more
wiley   +1 more source

Unconventional Secretion of Angiogenic Sonic Hedgehog-Containing Extra-Large Extracellular Vesicles is Driven by PI3K-Rab18-GDP Signalling. [PDF]

J Extracell Biol
Wang S, Imai R, Kaneko Y, Tanaka Y.
europepmc   +1 more source

Klhl31 is assocaited with skeletal myogenesis and its expression is regulated by myogenic signals and Myf-5 [PDF]

, 2009
Adams, Alaa Abou-Elhamd, Alvares, Andrea Münsterberg, Angers, Boardman, Borello, Bork, Borycki, Borycki, Borycki, Brent, Buckingham, Christ, Delfini, Dietrich, Dietrich, Fan, Geetha-Loganathan, Gros, Hamburger, Hara, Hollyday, Marcelle, McDermott, Münsterberg, Münsterberg, Oliver Cooper, Pownall, Pownall, Scaal, Schmidt, Schmidt, Schubert, Smith, Stogios, Stogios, Summerbell, Sweetman, Tajbakhsh, Wu, Xue, Yu   +42 more
core   +1 more source

RNA‐Sequencing Reveals Two Subgroups of Eccrine Porocarcinomas and Poromas

Journal of Cellular and Molecular Medicine, Volume 30, Issue 8, April 2026.
ABSTRACT Eccrine porocarcinoma (EPC), a rare malignant eccrine gland tumour, remains molecularly understudied. Transcriptomic studies of EPC and benign eccrine poroma (EP) have identified recurrent fusions and expression changes, but differences distinguishing malignant EPC from benign EP are unclear.
Maya Puttonen, Sami Kilpinen, Maria von Willebrand, Kalle Ojala, Tom Böhling, Virve Koljonen, Harri Sihto   +6 more
wiley   +1 more source

Sonic Hedgehog Agonists Induce Repair Schwann Cells. [PDF]

Biotechnol Bioeng
Colchado D, Schofield JB, Hunter DA, Xia X, Yang M, Sacks JM, Wood MD, Li X.   +7 more
europepmc   +1 more source

Cardioprotective effects of prolyl hydroxylase inhibitors during reperfusion in myocardial infarction: A study using cardiosphere‐derived cells

Experimental Physiology, Volume 111, Issue 4, Page 2058-2072, 1 April 2026.
Abstract Cardiosphere‐derived cells (CDCs) are a promising in vitro model for studying myocardial ischaemia–reperfusion (I–R) injury and testing potential therapeutic interventions. This study investigated the suitability of CDCs as a model for myocardial infarction (MI) and the effects of prolyl hydroxylase inhibitor (PHI) administration during ...
Luca Salhöfer, Ulrike B. Hendgen‐Cotta, Joachim Fandrey, Timm Schreiber, Tristan Leu   +4 more
wiley   +1 more source