Results 51 to 60 of about 6,536 (227)

Sonodynamic therapy reduces iron retention of hemorrhagic plaque [PDF]

Bioengineering & Translational Medicine, 2020
Abstract Intraplaque hemorrhage (IPH) plays a major role in the aggressive progression of vulnerable plaque, leading to acute cardiovascular events. We previously demonstrated that sonodynamic therapy (SDT) inhibits atherosclerotic plaque progression.
Bicheng Li, Jie Gong, Siqi Sheng, Minqiao Lu, Shuyuan Guo, Jianting Yao, Haiyu Zhang, Xuezhu Zhao, Zhengyu Cao, Xin Sun, Huan Wang, Yang Cao, Yongxing Jiang, Zhen Tian, Bin Liu, Hua Zhao, Zhiguo Zhang, Hong Jin, Ye Tian   +18 more
openaire   +3 more sources

Magnetically actuated sonodynamic nanorobot collectives for potentiated ovarian cancer therapy

Frontiers in Bioengineering and Biotechnology
Ovarian cancer presents a substantial challenge due to its high mortality and recurrence rates among gynecological tumors. Existing clinical chemotherapy treatments are notably limited by drug resistance and systemic toxic side effects caused by off ...
Yixuan Zhou, Yixuan Zhou, Ziqi Cao, Lixian Jiang, Ying Chen, Xiaoyu Cui, Jianrong Wu, Xue Xie, Longchen Wang, Tao Ying, Tao Ying   +10 more
doaj   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

Advanced Materials Interfaces, EarlyView.
xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing, Chen Hong, Fan Weijing, Huang Renyan, You Yang, Liu Guobin   +5 more
wiley   +1 more source

Sonodynamic therapy in combination with photodynamic therapy shows enhanced long-term cure of brain tumor

Scientific Reports, 2020
This article presents the construction of a multimodality platform that can be used for efficient destruction of brain tumor by a combination of photodynamic and sonodynamic therapy.
Ballav M. Borah, Joseph Cacaccio, Farukh A. Durrani, Wiam Bshara, Steven G. Turowski, Joseph A. Spernyak, Ravindra K. Pandey   +6 more
doaj   +1 more source

Dual Acting Polymeric Nano-Aggregates for Liver Cancer Therapy [PDF]

, 2018
Liver cancer treatments are often hindered by poor drug physicochemical properties, hence there is a need for improvement in order to increase patient survival and outlook.
Al-Shakarchi, W, Alsuraifi, A, Curtis, A, Hoskins, C   +3 more
core   +4 more sources

New perspectives for eye-sparing treatment strategies in primary uveal melanoma [PDF]

, 2022
Uveal melanoma is the most common intraocular malignancy and arises from melanocytes in the choroid, ciliary body, or iris. The current eye-sparing treatment options include surgical treatment, plaque brachytherapy, proton beam radiotherapy, stereotactic
Bilmin K., Czarnecka A. M., Fiedorowicz M., Kujawska T., Merks P., Rejdak R., Solnik M., Spalek M. J., Synoradzki K. J., Toro M. D.   +9 more
core   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Biomimetic Metal-Organic Framework Nanoparticles for Synergistic Combining of SDT-Chemotherapy Induce Pyroptosis in Gastric Cancer

Frontiers in Bioengineering and Biotechnology, 2022
In recent years, sonodynamic therapy (SDT) has been widely developed for cancer research as a promising non-invasive therapeutic strategy. Here, we synthesized zeolitic imidazole frameworks-8 (ZIF-8) and utilized its properties to encapsulate hydrophobic
Zhu Yu, Zhu Yu, Wenlong Cao, Wenlong Cao, Chuangye Han, Zhen Wang, Zhen Wang, Yue Qiu, Yue Qiu, Jiancheng Wang, Jiancheng Wang, Mengda Wei, Mengda Wei, Junfu Wang, Junfu Wang, Siwen Zhang, Siwen Zhang, Senfeng Liu, Shutian Mo, Junqiang Chen, Junqiang Chen   +20 more
doaj   +1 more source

Intracellular Reactive Oxygen Species Generation Induced by High‐Frequency Ultrasound in Thickness Vibration Mode

Advanced Science, EarlyView.
Cell‐sized high‐frequency ultrasound using a lithium niobate transducer, previously ignored in reactive oxygen species (ROS) production, generated intracellular ROS at frequencies higher than conventionally used. The intracellular generation of ROS by cell‐sized high‐frequency ultrasound revealed in this study is expected to be applied to innovative ...
Kotaro Fujishiro, Satoshi Okada, Filippo Rossi, Takahiro Kuchimaru, Yuta Kurashina   +4 more
wiley   +1 more source

Overcoming breast cancer cell treatment resistance by optimizing sonodynamic therapy and radiation sensitizers on lncRNA PVT1 and miR-1204 expression

Photodiagnosis and Photodynamic Therapy
Background: Acoustic cavitation is a foundational mechanism in ultrasound therapy, primarily through inertial cavitation resulting from microbubble collapse.
Ali Neshastehriz, Zeinab Hormozi-Moghaddam, Zahra Abedi Kichi, Seyedeh Mona Taheri, Seyed Mohammad Amini, Amir Aghaei   +5 more
doaj   +1 more source