Results 41 to 50 of about 6,219 (205)
Cardiovascular Diabetology, 2017 Context A previous genome-wide association study showed that a genetic variant of sortilin was associated with the risk of coronary artery disease (CAD). However, the role of circulating sortilin is still unknown.
Tae Jung Oh +9 more
doaj +1 more source
Carbamylated sortilin associates with cardiovascular calcification in patients with chronic kidney disease. [PDF]
, 2022 Sortilin, an intracellular sorting receptor, has been identified as a cardiovascular risk factor in the general population. Patients with chronic kidney disease (CKD) are highly susceptible to develop cardiovascular complications such as calcification ...
Kaesler, Nadine +21 more
core +1 more source
Sortilin and the risk of cardiovascular disease
Revista Portuguesa de Cardiologia (English Edition), 2013 Plasma low-density lipoprotein cholesterol (LDL-C) levels are a key determinant of the risk of cardiovascular disease, which is why many studies have attempted to elucidate the pathways that regulate its metabolism. Novel latest-generation sequencing techniques have identified a strong association between the 1p13 locus and the risk of cardiovascular ...
Maria Francisca, Coutinho +3 more
openaire +2 more sources
Regional and Cellular Mapping of Sortilin Immunoreactivity in Adult Human Brain
Frontiers in Neuroanatomy, 2019 Sortilin is a member of the vacuolar protein sorting 10 protein (VPS10P) domain receptor family, which carries out signal transduction and protein transport in cells.
Shu-Yin Xu +12 more
doaj +1 more source
Neural Regeneration Research, 2020 Prolonged activation of adenosine A1 receptor likely leads to damage of dopaminergic neurons and subsequent development of neurodegenerative diseases.
Yun-Cheng Lv +9 more
doaj +1 more source
Neoplasia: An International Journal for Oncology Research, 2018 Neurotensin (NTS), a 13–amino acid peptide which is distributed predominantly along gastrointestinal tract, has multiple physiologic and pathologic functions, and its effects are mediated by three distinct NTS receptors (NTSRs).
Ji Tae Kim +5 more
doaj +1 more source
Cardiovascular Diabetology, 2020 Background Peripheral artery disease (PAD) represents one of the most relevant vascular complications of type 2 diabetes mellitus (T2DM). Moreover, T2DM patients suffering from PAD have an increased risk of major adverse cardiovascular events (MACE) and ...
Federico Biscetti +12 more
doaj +1 more source
Science-Business eXchange, 2010 The largest ever genomewide association study meta-analysis has led to the identification of 59 new genetic variants associated with plasma lipid levels. The researchers have partnered with Alnylam Pharmaceuticals to elucidate how to target one of the leads, sortilin 1, in cardiovascular disease.
openaire +1 more source
Maternal serum sortilin levels in gestational diabetes mellitus
, 2021 Objective To evaluate the serum sortilin levels in pregnant women with gestational diabetes mellitus (GDM) and to compare the results with normoglycemic healthy pregnant women and observe the relationship between serum sortilin levels and biochemical ...
ÖZALP, MİRAÇ +7 more
core +1 more source
Developmental Dynamics, EarlyView.Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini +2 more
wiley +1 more source