Results 121 to 130 of about 545,864 (271)

The PX‐BAR membrane‐remodeling unit of sorting nexin 9 [PDF]

open access: yesThe EMBO Journal, 2007
Sorting nexins (SNXs) form a family of proteins known to interact with components in the endosomal system and to regulate various steps of vesicle transport. Sorting nexin 9 (SNX9) is involved in the late stages of clathrin-mediated endocytosis in non-neuronal cells, where together with the GTPase dynamin, it participates in the formation and scission ...
Pylypenko, Olena   +4 more
openaire   +3 more sources

SNX1 inhibits human ovarian cancer progression via regulation of the cell cycle, apoptosis and migration

open access: yesMolecular & Cellular Oncology
Sorting nexin 1 (SNX1), a member of the sorting nexin family, has been implicated in various cellular processes, yet its role in ovarian cancer (OV) remains poorly characterized.
Pin Li   +5 more
doaj   +1 more source

On the fate of early endosomes [PDF]

open access: yes, 2017
Proteins are endocytosed by various pathways into the cell. All these pathways converge at the level of the early endosome. The fate of the early endosome and how proteins are sorted into recycling and late endosomes/multi-vesicular body is a matter of ...
Spang, Anne
core  

Structural insights into how vacuolar sorting receptor recognizes the C‐terminal sorting determinant of a vicilin‐like seed storage protein

open access: yesThe FEBS Journal, Volume 293, Issue 1, Page 257-270, January 2026.
Soluble cargo proteins are sorted to the vacuoles via a receptor‐mediated mechanism. Combining crystallographic and mutagenesis studies, we showed how the C‐terminal sorting determinant (ctVSD) of vicilin‐like seed storage protein VL22 is recognized by the protease‐associated domain of Arabidopsis vacuolar‐sorting receptor 1.
Shu Nga Lui   +4 more
wiley   +1 more source

SNX25 regulates proinflammatory cytokine expression via the NF-κB signal in macrophages.

open access: yesPLoS ONE, 2021
Innate immunity is the first line of defense against bacterial infection and is initiated by macrophages. Sorting nexin 25 (SNX25) is an SNX family member and is reported to negatively regulate TGF-β signaling by enhancing TGF receptor degradation ...
Kazuya Nishimura   +4 more
doaj   +1 more source

A Robust Gene Expression Prognostic Signature for Overall Survival in High-Grade Serous Ovarian Cancer. [PDF]

open access: yes, 2019
The objective of this research was to develop a robust gene expression-based prognostic signature and scoring system for predicting overall survival (OS) of patients with high-grade serous ovarian cancer (HGSOC).
Hang, Bo   +8 more
core  

Analysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein processing [PDF]

open access: yes, 2018
The processing of amyloid precursor protein (APP) to the neurotoxic pro-aggregatory Aβ peptide is controlled by the mechanisms that govern the trafficking and localisation of APP.
Breusegem, Sophia   +2 more
core   +1 more source

Phylogeny, systematics and evolution of mimicry patterns in Neotropical limenitidine butterflies

open access: yesSystematic Entomology, Volume 51, Issue 1, January‐March 2026.
The most comprehensive phylogeny for Adelpha reveals that it is not monophyletic, supporting the description of the new genus Adelphina for the alala‐group. The rate of mimicry evolution increases towards the tropics, consistent with the hypothesis of stronger biotic interactions near the equator.
Erika Páez V.   +17 more
wiley   +1 more source

Generation of induced pluripotent stem cells (ARO-iPSC1-11) from a patient with autosomal recessive osteopetrosis harboring the c.212 + 1G > T mutation in SNX10 gene

open access: yesStem Cell Research, 2017
Pathogenic sequence variants in the Sorting Nexin 10 (SNX10) gene have been associated with autosomal recessive osteopetrosis (ARO) in human. In this study, an induced pluripotent stem cell (iPSC) line (ARO-iPSC1-11) was generated from an ARO patient ...
Maojia Xu   +3 more
doaj   +1 more source

Mechanisms of Membrane Curvature Generation in Membrane Traffic [PDF]

open access: yes, 2012
During the vesicular trafficking process, cellular membranes undergo dynamic morphological changes, in particular at the vesicle generation and fusion steps.
Hiroyuki Takatsu   +2 more
core   +3 more sources

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