Results 151 to 160 of about 545,864 (271)

Role of Retromer Complex in Neurodegenerative Diseases

Frontiers in Aging Neuroscience, 2016
Retromer is a protein complex that plays a central role in endosomal trafficking, and retromer dysfunction has been linked to a growing number of neurological disorders.
Li eChaosi, Syed Zahid Ali Shah, Zhao eDeming, Lifeng eYang   +3 more
doaj   +1 more source

Amyloid β-protein oligomers upregulate the β-secretase, BACE1, through a post-translational mechanism involving its altered subcellular distribution in neurons [PDF]

, 2015
Quantification of fluorescence intensities in axons and dendrites. After double immunofluorescent staining of primary neurons with anti-BACE1 (green) and anti-MAP2 (red) antibodies, specimens were examined under a LSM780 microscope.
Ai Hosaka, Akira Tamaoka, Daisuke Tanokashira, Fuyuki Kametani, Naomi Mamada, Wataru Araki   +5 more
core   +4 more sources

Intracellular trafficking of begomoviruses in the midgut cells of their insect vector.

PLoS Pathogens, 2018
Begomoviruses are exclusively transmitted by whiteflies in a persistent circulative manner and cause considerable economic losses to crop production worldwide.
Wen-Qiang Xia, Yan Liang, Yao Chi, Li-Long Pan, Jing Zhao, Shu-Sheng Liu, Xiao-Wei Wang   +6 more
doaj   +1 more source

SNX27: A trans-species cognitive modulator with implications for anxiety and stress susceptibility

Neurobiology of Stress
Sorting Nexin 27 (SNX27) is a brain-enriched endosome-associated cargo adaptor that shapes excitatory control, being relevant for cognitive and reward processing, and for several neurological conditions.
Gisela Armada, Susana Roque, Cláudia Serre-Miranda, Liliana Ferreira, Ana Vale, Ana João Rodrigues, Wanjin Hong, Margarida Correia-Neves, Neide Vieira   +8 more
doaj   +1 more source

CHARACTERIZATION OF THE UBIQUITIN LIGASE, UBE4B, IN ENDOCYTIC TRAFFICKING [PDF]

, 2017
Endocytosis is a process by which cells internalize membrane proteins to remove them from the plasma membrane, allowing cells to regulate the cell surface expression of transmembrane proteins.
Sirisaengtaksin, Natalie, Sirisaengtaksin, Natalie   +1 more
core   +1 more source

Higher order assembly of Sorting Nexin 16 controls tubulation and distribution of neuronal endosomes [PDF]

, 2018
Shiyu Wang, Zechuan Zhao, Avital A. Rodal   +2 more
openalex   +1 more source

Sorting nexin 17 facilitates LRP recycling in the early endosome [PDF]

, 2005
Peter van Kerkhof, Jiyeon Lee, Lynn M. McCormick, Elena Tetrault, Wenyan Lü, Marissa J. Schoenfish, Viola Oorschot, Ger J. Strous, Judith Klumperman, Guojun Bu   +9 more
openalex   +1 more source

Recognition and remodeling of endosomal zones by sorting nexins

Biochimica et Biophysica Acta (BBA) - Biomembranes
The proteolipid code determines how cytosolic proteins find and remodel membrane surfaces. Here, we investigate how this process works with sorting nexins Snx1 and Snx3. Both proteins form sorting machines by recognizing membrane zones enriched in phosphatidylinositol 3-phosphate (PI3P), phosphatidylserine (PS) and cholesterol.
Michael Overduin, Rakesh Bhat
openaire   +2 more sources

Circulating Anti-Sorting Nexins 16 Antibodies as an Emerging Biomarker of Coronary Artery Disease in Patients with Obstructive Sleep Apnea

, 2020
Yusuke Katsumata, Jiro Terada, Takuma Matsumura, Ken Koshikawa, Seiichiro Sakao, Go Tomiyoshi, Natsuko Shinmen, Rika Nakamura, Hideyuki Kuroda, Kengo Nagashima, Yoshio Kobayashi, Eiichi Kobayashi, Yasuo Iwadate, Xiaomeng Zhang, Takaki Hiwasa, Koichiro Tatsumi   +15 more
openalex   +1 more source

CHC22 clathrin recruitment to the early secretory pathway requires two-site interaction with SNX5 and p115

The EMBO Journal
The two clathrin isoforms, CHC17 and CHC22, mediate separate intracellular transport routes. CHC17 performs endocytosis and housekeeping membrane traffic in all cells.
Joshua Greig, George T Bates, Daowen I Yin, Kit Briant, Boris Simonetti, Peter J Cullen, Frances M Brodsky   +6 more
doaj   +1 more source