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A Critical Role for Sorting Nexin 1 in the Trafficking of Metabotropic Glutamate Receptors. [PDF]
Sharma R, Gulia R, Bhattacharyya S.
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β-Adrenergic Receptor Recycles Via a Membranous Organelle, Recycling Endosome, by Binding with Sorting Nexin27 [PDF]
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Sorting nexin-21 is a scaffold for the endosomal recruitment of huntingtin.
Danson CM +3 more
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Sorting Nexin 9 facilitates podocin endocytosis in the injured podocyte
有 佐々木
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SNX17 regulates Notch pathway and pancreas development through the retromer-dependent recycling of Jag1 [PDF]
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Sorting out the cellular functions of sorting nexins
Nature Reviews Molecular Cell Biology, 2002Sorting nexins are a diverse group of cellular trafficking proteins that are unified by the presence of a phospholipid-binding motif - the PX domain. The ability of these proteins to bind specific phospholipids, as well as their propensity to form protein-protein complexes, points to a role for these proteins in membrane trafficking and protein sorting.
Carolyn A, Worby, Jack E, Dixon
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Retromer and sorting nexins in endosomal sorting
Biochemical Society Transactions, 2015The evolutionarily conserved endosomal retromer complex rescues transmembrane proteins from the lysosomal degradative pathway and facilitates their recycling to other cellular compartments. Retromer functions in conjunction with numerous associated proteins, including select members of the sorting nexin (SNX) family.
Matthew, Gallon, Peter J, Cullen
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Tissue-specific regulatory role of Sorting Nexin 27 in the intestinal inflammation
Physiology, 2023The sorting nexin (SNX) family involves in endocytosis and protein trafficking. SNX27 specifically binds and directs the sorting transmembrane proteins containing PDZ-binding motif and is critical in protein-protein interactions in various organs.
Jilei Zhang +6 more
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