Results 31 to 40 of about 545,864 (271)

Sorting nexin 17 increases low-density lipoprotein receptor-related protein 4 membrane expression: A novel mechanism of acetylcholine receptor aggregation in myasthenia gravis. [PDF]

Front Immunol, 2022
Myasthenia gravis (MG) is characterized by autoimmune damage to the postsynaptic membrane of the neuromuscular junction (NMJ) with impaired postsynaptic acetylcholine receptor (AChR) aggregation.
He X, Zhou S, Ji Y, Zhang Y, Lv J, Quan S, Zhang J, Zhao X, Cui W, Li W, Liu P, Zhang L, Shen T, Fang H, Yang J, Zhang Y, Cui X, Zhang Q, Gao F.   +18 more
europepmc   +2 more sources

Sorting nexin 6 interacts with Cullin3 and regulates programmed death ligand 1 expression. [PDF]

FEBS Lett, 2021
Programmed death ligand 1 (PD‐L1) is critical for the ability of cancer cells to evade attacks by the host immune system. However, the molecular mechanisms controlling PD‐L1 expression have not been fully understood.
Ghosh C, Xing Y, Li S, Hoyle RG, Sun M, Li J, Sun Y.   +6 more
europepmc   +2 more sources

Sorting nexin 17 regulates ApoER2 recycling and reelin signaling.

PLoS ONE, 2014
ApoER2 is a member of the low density-lipoprotein receptor (LDL-R) family. As a receptor for reelin, ApoER2 participates in neuronal migration during development as well as synaptic plasticity and survival in the adult brain.
Pablo Sotelo, Pamela Farfán, María Luisa Benitez, Guojun Bu, María-Paz Marzolo   +4 more
doaj   +6 more sources

Loss of Intestinal Endosome-associated Protein Sorting Nexin 27 Disrupts Epithelial Barrier and Promotes Inflammation. [PDF]

Cell Mol Gastroenterol Hepatol
Deb S, Zhang Y, An Y, Xia Y, Sun J.
europepmc   +3 more sources

Structural basis for the hijacking of endosomal sorting nexin proteins by Chlamydia trachomatis

eLife, 2017
During infection chlamydial pathogens form an intracellular membrane-bound replicative niche termed the inclusion, which is enriched with bacterial transmembrane proteins called Incs.
Blessy Paul, Hyun Sung Kim, Markus C Kerr, Wilhelmina M Huston, Rohan D Teasdale, Brett M Collins   +5 more
doaj   +2 more sources

The Essential Role of Sorting Nexin 5 in Virus-Induced Autophagy [PDF]

Frontiers in Immunology, 2022
Dong-Yi Li, Jun-Hao Wen, Shan Liang, Ji-Xin Tang   +3 more
doaj   +2 more sources

Sorting nexin 1 loss results in increased oxidative stress and hypertension. [PDF]

FASEB J, 2020
Yang J, Asico LD, Beitelshees AL, Feranil JB, Wang X, Jones JE, Armando I, Cuevas SG, Schwartz GL, Gums JG, Chapman AB, Turner ST, Boerwinkle E, Cooper-DeHoff RM, Johnson JA, Felder RA, Weinman EJ, Zeng C, Jose PA, Villar VAM.   +19 more
europepmc   +3 more sources

SNX3 (Sorting Nexin 3) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2020
Sorting Nexin 3 (SNX3) gene maps to chromosome 6, minus strand and has 4 exons and 3 introns. There are 3 alternatively spliced isoforms (transcripts). SNX3 is a member of the sorting nexin family. Members of this family generally have BAR domains and phosphoinositide binding regions called the phox (PX) domain, and are involved in intracellular ...
Esra Çiçek, Ayca Circir Hatil, Merve Oyken, Harun Cingoz, Ayşe Elif Erson-Bensan   +4 more
openalex   +3 more sources

Endosomal localization and function of sorting nexin 1 [PDF]

Proceedings of the National Academy of Sciences, 2002
There are 17 human members of the sorting nexin (SNX) family of proteins that contain Phox (PX) domains. Yeast orthologs function in vesicular trafficking and mammalian proteins have been implicated in endocytic trafficking of cell surface receptors.
Qi Zhong, Cheri S. Lazar, Hélène Tronchère, Trey K. Sato, Timo Meerloo, Michele Yeo, Zhou Songyang, Scott D. Emr, Gordon N. Gill   +8 more
openalex   +5 more sources

Erratum for the Research Article: "Inhibiting sorting nexin 10 promotes mucosal healing through SREBP2-mediated stemness restoration of intestinal stem cells" by Bao et al.

Sci Adv
europepmc   +2 more sources