Results 41 to 50 of about 545,864 (271)
Sorting nexin 3 induces heart failure via promoting retromer-dependent nuclear trafficking of STAT3. [PDF]
Cell Death Differ, 2021 Lu J +11 more
europepmc +2 more sources
Prognostic significance of sorting nexin family of osteosarcoma: A novel prognostic model
Asian Journal of SurgeryYongchao Wang, Rui Liu, Dexin Wang
doaj +2 more sources
Sorting Nexins in Protein Homeostasis [PDF]
Cells, 2020 Sorting nexins (SNXs) are a highly conserved membrane-associated protein family that plays a role in regulating protein homeostasis. This family of proteins is unified by their characteristic phox (PX) phosphoinositides binding domain. Along with binding to membranes, this family of SNXs also comprises a diverse array of protein-protein interaction ...
Cooper, Katrina F., Hanley, Sarah E.
openaire +3 more sources
SNX12 role in endosome membrane transport. [PDF]
PLoS ONE, 2012 In this paper, we investigated the role of sorting nexin 12 (SNX12) in the endocytic pathway. SNX12 is a member of the PX domain-containing sorting nexin family and shares high homology with SNX3, which plays a central role in the formation of ...
Véronique Pons +5 more
doaj +1 more source
Navigating the Controversies of Retromer-Mediated Endosomal Protein Sorting
Frontiers in Cell and Developmental Biology, 2021 The retromer complex was first identified more than 20 years ago through studies conducted in the yeast Saccharomyces cerevisiae. Data obtained using many different model systems have revealed that retromer is a key component of the endosomal protein ...
Yingfeng Tu, Matthew N. J. Seaman
doaj +1 more source
snz/SNX25 at the crossroad of endocytosis and lipid handling in autophagy
Autophagy Reports, 2022 Macroautophagy/autophagy is coupled to a myriad of intracellular processes, among which vesicular trafficking is an important contributor of membranes and proteins required at various stages, from autophagosome formation to degradation.
Annie Lauzier, Steve Jean
doaj +1 more source
An evolving understanding of sorting signals for endosomal retrieval
iScience, 2022 Summary: Complex mechanisms govern the sorting of membrane (cargo) proteins at endosomes to ensure that protein localization to the post-Golgi endomembrane system is accurately maintained.
Xin Yong +3 more
doaj +1 more source
Toward Understanding the Molecular Role of SNX27/Retromer in Human Health and Disease
Frontiers in Cell and Developmental Biology, 2021 Aberrations in membrane trafficking pathways have profound effects in cellular dynamics of cellular sorting processes and can drive severe physiological outcomes.
Mintu Chandra +6 more
doaj +1 more source
Journal of Fungi, 2022 Cellular recycling via autophagy-associated proteins is a key catabolic pathway critical to invasive fungal pathogen growth and virulence in the nutrient-limited host environment.
E. Keats Shwab +8 more
doaj +1 more source
Cargo selectivity of yeast sorting nexins [PDF]
Traffic, 2017 Sorting nexins are PX domain‐containing proteins that bind phospholipids and often act in membrane trafficking where they help to select cargo. However, the functions and cargo specificities of many sorting nexins are unknown. Here, a high‐throughput imaging screen was used to identify new sorting nexin cargo in the yeast Saccharomyces cerevisiae ...
Björn D.M. Bean +2 more
openaire +2 more sources