Results 191 to 200 of about 29,104 (247)

The Imperative of Involving Nurses When Reviewing Psychiatric Medication: a Qualitative Study of Implementing Physician‐Led Medication Reviews for Psychiatric Outpatients With Diabetes

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.
ABSTRACT Background We previously found that implementing medication reviews by a physician specialised in clinical pharmacology at interdisciplinary conferences with prescribing physicians and nurses led to a relative reduction in the number of drugs and potentially inappropriate prescriptions (PIPs) in psychiatric outpatients with diabetes.
Johan Frederik Mebus Meyer Christensen, Elisabeth Mebus Meyer Christensen, Ulla Christensen, Signe Düring, Gesche Jürgens   +4 more
wiley   +1 more source

The amino terminal domain of the human α7 nicotinic acetylcholine receptor subunit leads to the functional expression of human/insect receptors

British Journal of Pharmacology, Volume 183, Issue 13, Page 3517-3537, July 2026.
Human α7 receptors have been characterised in terms of pharmacological properties. Insertion of the N‐terminal domain of the human α7 subunit leads to honeybee and cockroach chimeric receptors activated by ACh and inhibited by α‐Bgt. Insertion of the human cys‐loop leads to cockroach chimeric receptors modulated by PNU.
Alison Cartereau, Chloé Veront, Alexandra Cremades, Priscilla Martin, Remi Gojard, Nicolas Galland, Emiliane Taillebois, Dieudonnée Togbé, Jean‐Yves Le Questel, Steeve H. Thany   +9 more
wiley   +1 more source

Ph‐Negative Acute Lymphoblastic Leukemia in the Older Adults: Biology, Therapeutic Strategies and Unmet Needs

European Journal of Haematology, Volume 117, Issue 1, Page 24-41, July 2026.
ABSTRACT Acute lymphoblastic leukaemia (ALL) in older adults represents a growing clinical challenge, driven by an ageing population, adverse disease biology, and reduced tolerance to intensive chemotherapy. Although pediatric‐inspired regimens have improved outcomes in younger adults with Philadelphia chromosome (Ph)‐negative ALL, survival in older ...
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Santino Caserta, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Marco Fiorillo, Nicola Amodio, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Targeting the Menin–KMT2A Axis in Acute Leukemia: From Epigenetic Dependency to Clinical Translation

European Journal of Haematology, Volume 117, Issue 1, Page 132-143, July 2026.
ABSTRACT Acute leukemias characterized by a shared epigenetic dependency on the menin–KMT2A axis rely on aberrant HOX‐driven transcriptional programs that sustain leukemic self‐renewal and impair differentiation. This dependency is most evident in KMT2A‐rearranged and NPM1‐mutated acute myeloid leukemia (AML), but also extends to other HOX‐dependent ...
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Santino Caserta, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Mamdouh Skafi, Nicola Amodio, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Stomatal Decoupling From Photosynthesis Under High Temperatures Is Consistent With Stomatal Optimisation

Global Change Biology, Volume 32, Issue 7, July 2026.
Many leaf gas exchange models predict that photosynthesis and stomatal conductance are tightly coupled and respond in parallel to changing environmental conditions. However, experiments show that when temperatures increase beyond the thermal optimum of photosynthesis, stomatal conductance may continue to rise while photosynthesis declines, facilitating
Simon R. G. Jones, Georg Wohlfahrt, Andrew D. Friend, Peter J. Franks, Alexander W. Cheesman, Lucas A. Cernusak, Haoyu Diao, Xiaolong Feng, Josef Urban, Tyeen Taylor, Martijn Slot, Lina M. Mercado, Peter M. Cox   +12 more
wiley   +1 more source

Thermally Activated Deformation Mechanisms in MgO Investigated via High Temperature Scanning Indentation

Journal of the American Ceramic Society, Volume 109, Issue 7, July 2026.
ABSTRACT Magnesium oxide (MgO) serves as a model material for plastically deformable ceramics. In previous studies, it has mainly been investigated via uniaxial compression, with studies often focusing on a particular deformation mechanism and temperature range. In this work, the novel high temperature scanning indentation (HTSI) nanoindentation method
Marcel Sos, Oliver Preuß, Sebastian Bruns, Karsten Durst   +3 more
wiley   +1 more source

To Beet or Not (Just) to Beet: Ecology, Virulence and Genomic Insights Into the Leaf Spot Disease Causative Pseudomonas syringae pv. aptata

Molecular Plant Pathology, Volume 27, Issue 7, July 2026.
We profile Pseudomonas syringae pv. aptata, causing bacterial leaf spot on chenopods and cucurbits, highlighting epidemiology, virulence mechanisms and integrated disease management strategies. ABSTRACT Taxonomy Kingdom Bacteria; Phylum Proteobacteria; Class Gammaproteobacteria; Family Pseudomonadaceae; Genus Pseudomonas; Species Pseudomonas syringae ...
Ivan Nikolić, Iva Rosić, Olja Medić, Tamara Ranković, Marina Sokić, Tanja Berić, Jelena Lozo, Slaviša Stanković   +7 more
wiley   +1 more source

The vesicle trafficking R‐SNARE VAMP714 connects auxin responses, ROS and ion homeostasis in Arabidopsis under salt stress

New Phytologist, Volume 251, Issue 1, Page 207-227, July 2026.
Network of VAMP714‐dependent interactions during salt stress. Summary Plant responses to salt stress include an altered root architecture mediated by ion imbalances, reactive oxygen species (ROS) accumulation, and altered hormonal responses. Auxin is implicated in these processes.
Jialei Sun, Julien Agneessens, Jennifer F. Topping, Keith Lindsey   +3 more
wiley   +1 more source

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4-Quinolones and the SOS response

Journal of Medical Microbiology, 1989
The SOS DNA repair system is induced in bacteria treated with 4-quinolones. However, whether the response exacerbates or repairs the damage caused by these drugs is still unclear. The recA13 and the recB21 mutations impair recombination repair and render bacteria unable to induce the SOS response when treated with nalidixic acid or other agents that ...
C S, Lewin, B M, Howard, N T, Ratcliffe, J T, Smith   +3 more
openaire   +2 more sources