Results 101 to 110 of about 11,099 (162)

An Additional Lrp4 High Bone Mass Mutation Mitigates the Sost-Knockout Phenotype in Mice by Increasing Bone Remodeling.

Pathogenic variants disrupting the binding between sclerostin (encoded by SOST) and its receptor LRP4 have previously been described to cause sclerosteosis, a rare high bone mass disorder.
Schinke, Thorsten, Boudin, Eveline, Van Hul, Wim, Steenackers, Ellen, Kramer, Ina, Mateiu, Ligia, Yorgan, Timur A., Hendrickx, Gretl, Kneissel, Michaela, Mortier, Geert   +9 more
core   +2 more sources

Relationship of serum calciprotein particles， sclerostin， and dehydroepiandrosterone with coronary artery calcification in maintenance hemodialysis patients

Linchuang shenzangbing zazhi
ObjectiveTo investigate the relationships between serum calciprotein particles （CPPs）， sclerostin （SOST）， and dehydroepiandrosterone （DHEA） and coronary artery calcification （CAC） in maintenance hemodialysis （MHD） patients， and to evaluate the diagnostic
Chai Wen-xiu, Tian Cong-cong, Guo Chen-huan, Yang Li-juan, Li Yun-xia, Li Yun   +5 more
doaj  

Global Deletion of Sost Increases Intervertebral Disc Hydration but May Trigger Compensation

, 2020
Intervertebral discs (IVD) degenerate earlier than many other musculoskeletal tissues and will continue to degenerate with aging. IVD degeneration affects up to 80 percent of the adult population and is a major contributing factor to low back pain.
Kroon, Tori
core  

Increased endothelial sclerostin caused by elevated DSCAM mediates multiple trisomy 21 phenotypes

The Journal of Clinical Investigation
Trisomy 21 (T21), a recurrent aneuploidy occurring in 1:800 births, predisposes to congenital heart disease (CHD) and multiple extracardiac phenotypes.
David M. McKean, Qi Zhang, Priyanka Narayan, Sarah U. Morton, Viktoria Strohmenger, Vi T. Tang, Sophie McAllister, Ananya Sharma, Daniel Quiat, Daniel Reichart, Daniel M. DeLaughter, Hiroko Wakimoto, Joshua M. Gorham, Kemar Brown, Barbara McDonough, Jon A. Willcox, Min Young Jang, Steven R. DePalma, Tarsha Ward, Pediatric Cardiac Genomics Consortium Investigators, Richard Kim, John D. Cleveland, J.G. Seidman, Christine E. Seidman   +23 more
doaj   +1 more source

PKC Inhibition by Gö6976 Promotes Osteogenic Differentiation of Dental Follicle Cells Involving Rho-Dependent Pathway Dynamics. [PDF]

Biomedicines
Morsczeck C, Reck A, Bodensteiner T, Reichert TE, Beck HC.   +4 more
europepmc   +1 more source

A Comparative Study on the Influence of Zirconia and Titanium Nanoparticles on the Functionality of Osteocytes In Vitro. [PDF]

Int J Dent
Matouk MH, Aghila Rani KG, Kheder W, Ismail A, Samsudin AR, AlKawas S.   +5 more
europepmc   +1 more source

Osteocyte Mechanobiology in Peri-Implant Bone Adaptation: A Narrative Review and Hypothesis-Generating Framework for SOST/Wnt-Linked Cortical Stability. [PDF]

Cells
Kuc AE, Sulewska M, Hajduk G, Kuc P, Kuc N, Lis J, Kawala B, Sarul M.   +7 more
europepmc   +1 more source

Osteoblastic sclerostin loop3-LRP4 interaction required by sclerostin to inhibit bone formation. [PDF]

Bone Res
Wang L, Tao X, Jiang H, Ding S, Zhang N, Yang X, Wang S, Zhang Y, Li N, Li H, Li Z, Wen X, Sun M, Zhong C, So H, Liu J, Yu Y, Yue H, Luo X, Ferdinandy P, Zhang T, Zhang S, Zhang Z, Lu A, Zhang B, Zhang G.   +25 more
europepmc   +1 more source

CSF galanin and noradrenaline downregulation by psilocybin therapy in major depressive disorder. [PDF]

Neuropsychopharmacology
Paslawski W, Doyon D, Ekman CJ, Yngwe H, Mamula D, Zareba-Paslawska J, Beckman M, Xu ZD, Hökfelt T, Tiger M, Lundberg J, Svenningsson P.   +11 more
europepmc   +1 more source

Circulating Wnt Signaling Inhibitors and Osteoprotegerin in Women with Newly Diagnosed Overt Thyroid Dysfunction. [PDF]

Metabolites
Miteva MZ, Orbetzova MM, Nonchev BI, Davcheva DM, Gigov K.   +4 more
europepmc   +1 more source