Results 171 to 180 of about 70,586 (295)

Supplementary methods from Epigenetic Switch between <i>SOX2</i> and <i>SOX9</i> Regulates Cancer Cell Plasticity

, 2023
Sheng‐Chieh Lin, Yu‐Ting Chou, Shih Sheng Jiang, Junn-Liang Chang, Chih‐Hung Chung, Yu-Rung Kao, I‐Shou Chang, Cheng‐Wen Wu   +7 more
openalex   +1 more source

Importance of SUMOylation Consensus Sequence of MAFK in Regulating EMT, Tumor Growth, Stemness, and Drug Resistance

Cancer Science, EarlyView.
In this study, we focused on SUMOylation, a posttranslational modification, and investigated the importance of its consensus sequence in MAFK. We demonstrated that the non‐SUMOylation mimic mutant MAFK (EA) impairs MAFK‐induced EMT, cellular migration and invasion, tumor and sphere formation, acquisition of stem‐like properties, and drug resistance ...
Thuy Linh Dang Cao, Yukari Okita, Reon Yahatabara, Manar A. Elhinnawi, Nuriza Ulul Azmi, Thanasis Poullikkas, Hozumi Motohashi, Mitsuyasu Kato   +7 more
wiley   +1 more source

SOX2 is a dispensable modulator of NUT carcinoma oncogenesis in mice. [PDF]

Life Sci Alliance
Luo C, Zheng D, Elnegiry A, Bhatara S, Mias GI, Tsoi MF, Yu J, Gu B.   +7 more
europepmc   +1 more source

Sox2 Transcriptionally Regulates Pqbp1, an Intellectual Disability-Microcephaly Causative Gene, in Neural Stem Progenitor Cells

, 2013
Chan Li, Hikaru Ito, Kyota Fujita, Hiroki Shiwaku, Yunlong Qi, Kazuhiko Tagawa, Takuya Tamura, Hitoshi Okazawa   +7 more
openalex   +2 more sources

Oesophageal Epithelial Cell‐Intrinsic MHCII Regulates Food Antigen‐Dependent Eosinophilic Esophagitis in an IFNγ‐Dependent Manner

Clinical &Experimental Allergy, EarlyView.
We found that oesophageal epithelial cells upregulate MHCII expression during active EoE in humans and a mouse model. MHCII expression by EECs was governed by IFNγ‐inducible transcriptional elements. EEC‐intrinsic MHCII promoted regulatory T cell accumulation and attenuated eosinophilic oesophageal inflammation.
Eric M. Rodríguez‐López, Rachel L. Clement, Megha Lal, Yusen Zhou, Stephen D. Carro, Charles‐Antoine Assenmacher, Ravi Gautam, Jarad Beers, Amanda B. Muir, Jonathan M. Spergel, Melanie A. Ruffner, Laurence C. Eisenlohr, David A. Hill   +12 more
wiley   +1 more source

SOX2 induces LPCAT1 expression to promote cholesterol metabolic reprogramming-mediated invasion and metastasis in osteosarcoma. [PDF]

Front Mol Biosci
Zhu L, Sun Y.
europepmc   +1 more source

DKK1 maintained cancer stem-like properties of esophageal carcinoma cells via ALDH1A1/SOX2 axis.

, 2017
Zhibin Lu, Cun‐Rong Zhou, Jiaojiao Hu, Lei Xiong, Zhuangzhuang Cong, Yi Shen   +5 more
openalex   +1 more source

Myeloid PD‐1 Regulates Astrocyte Development and Leads to Active Behaviours

Cell Proliferation, EarlyView.
During early neurodevelopment, PD‐1 ablation in myeloid cells influences myeloid proliferation/differentiation and causes sustained astrocyte overproliferation. PD‐1f/f; LysM‐Cre mice showed elevated astrocyte gene expression and behavioural changes.
Jie Qin, Chong Wang, Sihan Li, Yanyan Wang, Tingting He, Jianwei Jiao, Fen Ji   +6 more
wiley   +1 more source

Recent trend on sarcoma stem cell reprogramming towards study of disease progression: A systematic review. [PDF]

J Stem Cells Regen Med
Zulkifli NS, Ab-Rahim S, Muhamad M.
europepmc   +1 more source

Sex Determining Region Y-Box 2 (SOX2) Is a Potential Cell-Lineage Gene Highly Expressed in the Pathogenesis of Squamous Cell Carcinomas of the Lung

, 2010
Ping Yuan, Humam Kadara, Carmen Behrens, Ximing Tang, Denise M. Woods, Luisa M. Solis, Jiaoti Huang, Monica Spinola, Wenli Dong, Guosheng Yin, Junya Fujimoto, Edward Kim, Yang Xie, Luc Girard, César A. Moran, Waun Ki Hong, John D. Minna, Ignacio I. Wistuba   +17 more
openalex   +2 more sources