Results 181 to 190 of about 66,099 (245)

Sex Determining Region Y-Box 2 (SOX2) Is a Potential Cell-Lineage Gene Highly Expressed in the Pathogenesis of Squamous Cell Carcinomas of the Lung

, 2010
Ping Yuan, Humam Kadara, Carmen Behrens, Ximing Tang, Denise M. Woods, Luisa M. Solis, Jiaoti Huang, Monica Spinola, Wenli Dong, Guosheng Yin, Junya Fujimoto, Edward Kim, Yang Xie, Luc Girard, César A. Moran, Waun Ki Hong, John D. Minna, Ignacio I. Wistuba   +17 more
openalex   +2 more sources

Neural Organoids Protect Engineered Heart Tissues From Glucolipotoxicity by Transferring Versican in a Co‐Culture System

Cell Proliferation, EarlyView.
In this study, Bai et al. established a co‐culture system between neural organoids (NOs) and engineered heart tissues (EHTs) and demonstrated that NOs could secrete versican, which was absorbed by EHTs to ameliorate glucolipotoxicity. ABSTRACT Metabolic disorders could cause dysregulated glucose and lipid at the systemic level, but how inter‐tissue ...
Baochen Bai, Jiting Li, Ze Wang, Yuhan Yang, Jieqing He, Gonglie Chen, Yufan Zhang, Yan Qi, Zhongjun Wan, Lin Cai, Run Wang, Kai Wang, Dongyu Zhao, Jingzhong Zhang, Weihua Huang, Ronald X. Xu, Mingzhai Sun, Xiao Han, Yan Liu, Donghui Zhang, Wanying Zhu, Jian Liu, Yuxuan Guo   +22 more
wiley   +1 more source

AKT1 as a therapeutic target for platinum-resistant SOX2 positive ovarian cancer cells. [PDF]

Sci Rep
Xue M, Kang L, Zhang Y, Yuan X, Li J, Zhang R, Wong J.   +6 more
europepmc   +1 more source

EphB Signaling Directs Peripheral Nerve Regeneration through Sox2-Dependent Schwann Cell Sorting

, 2010
Simona Parrinello, Ilaria Napoli, Sara Ribeiro, Patrick Wingfield Digby, Marina Fedorova, David B. Parkinson, Robin D. S. Doddrell, Masanori Nakayama, Ralf H. Adams, Alison C. Lloyd   +9 more
openalex   +1 more source

FAM20C Modulates Neuronal Differentiation in Hypoxic–Ischemic Brain Damage via KAP1 Phosphorylation and LINE1 RNA m6A‐Dependent H3K9me3 Regulation

Cell Proliferation, EarlyView.
FAM20C regulates the composition of the YTHDC1‐NCL‐KAP1‐LINE1 RNAs complex, thereby affecting neuronal differentiation in hypoxic–ischemic brain damage (HIBD). ABSTRACT Neurodevelopmental impairment due to hypoxic–ischemic brain damage (HIBD) lacks effective biomarkers and therapeutic targets.
Chen‐xi Feng, Mei Wang, Gen Li, Si‐jia Chu, Di Wu, Xiao‐han Hu, Li‐xiao Xu, Mei Li, Xing Feng   +8 more
wiley   +1 more source

SOX2 Is an Oncogene Activated by Recurrent 3q26.3 Amplifications in Human Lung Squamous Cell Carcinomas

, 2010
Thomas Hussenet, Soraya Dali, Exinger Julien, Ben Monga, Bernard Jost, Doulaye Dembélé, Nadine Martinet, Christelle Thibault-Carpentier, Joerg Huelsken, Élisabeth Brambilla, Stanislas du Manoir   +10 more
openalex   +2 more sources

Tumour Cell Size Control and Its Impact on Tumour Cell Function

Cell Proliferation, EarlyView.
The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley   +1 more source

Single-cell transcriptomics of ventral forebrain progenitors identifies Evf2 enhancer lncRNA-enhancer gene guidance through direct RNA binding and RNP recruitment domains. [PDF]

Nat Commun
Li E, Chakraborty A, Kohtz SJ, Cajigas I, Hinojosa-Gonzalez L, Shiau F, Bertossi R, Vassar RJ, Kessler JA, Ay F, Clark BS, Kohtz JD.   +11 more
europepmc   +1 more source

Cell Type‐Specific IL‐5Rα Distribution and IL‐5‐Induced CCL11 Expression in Human Nasal Epithelium

Allergy, EarlyView.
Yosep Kim, Miran Kang, Juhee Seo, Subin Kim, Min‐Seok Rha, Chang‐Hoon Kim, Hyung‐Ju Cho   +6 more
wiley   +1 more source

Myeloid PD‐1 Regulates Astrocyte Development and Leads to Active Behaviours

Cell Proliferation, EarlyView.
During early neurodevelopment, PD‐1 ablation in myeloid cells influences myeloid proliferation/differentiation and causes sustained astrocyte overproliferation. PD‐1f/f; LysM‐Cre mice showed elevated astrocyte gene expression and behavioural changes.
Jie Qin, Chong Wang, Sihan Li, Yanyan Wang, Tingting He, Jianwei Jiao, Fen Ji   +6 more
wiley   +1 more source