Results 191 to 200 of about 70,586 (295)

Decoding the Role of Caveolin‐1 in Morphological Diversity and Self‐Renewal of Breast Cancer Cells

open access: yesCell Proliferation, EarlyView.
The silence of caveolin‐1 (Cav‐1) reproduced the morphological evolutionary behaviour of cancer cells, which is similar to the epithelial‐mesenchymal transition process. And Cav‐1 dependent morphological changes could affect cancer cell self‐renewal capacity through maintaining the morphological stability.
Shun Li   +14 more
wiley   +1 more source

Phosphatase PPP1CC Regulates the First Lineage Segregation by GAS5 in Mouse Preimplantation Embryos

open access: yesCell Proliferation, EarlyView.
Subcortical GAS5 directs PPP1CC phosphatase spatiotemporal positioning during mouse morula‐blastocyst transition, controlling YAP dephosphorylation to drive first embryonic lineage specification. ABSTRACT The transcriptional effector of the Hippo signalling pathway, YAP, regulates the first lineage specification in mouse preimplantation embryos ...
Jianwu Wang   +10 more
wiley   +1 more source

Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea [PDF]

open access: bronze, 2008
Alain Dabdoub   +6 more
openalex   +1 more source

Vascularised Brain Organoids: Engineering Strategies and Neurobiological Applications

open access: yesCell Proliferation, EarlyView.
This review highlights emerging strategies to engineer vascularized brain organoids—including endothelial co‐culture, genetic induction, perfusion systems, and in vivo transplantation—and their applications in modelling neurovascular diseases, evaluating BBB drug delivery, and advancing regenerative medicine.
Yeajin Song   +4 more
wiley   +1 more source

Genetic complexity in pediatric onset epilepsy‐movement disorder syndromes: Insights from a cohort of 97 subjects

open access: yesEpilepsia, EarlyView.
Abstract Objective Conditions presenting with both epilepsy and movement disorders (EPIMDs) range from relatively benign cases to severe developmental encephalopathies. However, the full clinical and genetic spectrum still needs to be better defined.
Davide Caputo   +15 more
wiley   +1 more source

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