Decoding the Role of Caveolin‐1 in Morphological Diversity and Self‐Renewal of Breast Cancer Cells
The silence of caveolin‐1 (Cav‐1) reproduced the morphological evolutionary behaviour of cancer cells, which is similar to the epithelial‐mesenchymal transition process. And Cav‐1 dependent morphological changes could affect cancer cell self‐renewal capacity through maintaining the morphological stability.
Shun Li +14 more
wiley +1 more source
Analysis of <i>OTX2</i>, <i>PAX6</i>, and <i>SOX2</i> Gene and Protein Expression Patterns in Ocular Development of Human and Rat Embryos. [PDF]
Junga A, Pilmane M, Fedirko P.
europepmc +1 more source
Phosphatase PPP1CC Regulates the First Lineage Segregation by GAS5 in Mouse Preimplantation Embryos
Subcortical GAS5 directs PPP1CC phosphatase spatiotemporal positioning during mouse morula‐blastocyst transition, controlling YAP dephosphorylation to drive first embryonic lineage specification. ABSTRACT The transcriptional effector of the Hippo signalling pathway, YAP, regulates the first lineage specification in mouse preimplantation embryos ...
Jianwu Wang +10 more
wiley +1 more source
Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review). [PDF]
Wang K +9 more
europepmc +1 more source
Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea [PDF]
Alain Dabdoub +6 more
openalex +1 more source
Vascularised Brain Organoids: Engineering Strategies and Neurobiological Applications
This review highlights emerging strategies to engineer vascularized brain organoids—including endothelial co‐culture, genetic induction, perfusion systems, and in vivo transplantation—and their applications in modelling neurovascular diseases, evaluating BBB drug delivery, and advancing regenerative medicine.
Yeajin Song +4 more
wiley +1 more source
Exosomal SNHG26 mediates immunosuppression by impairing NK cells in tongue cancer. [PDF]
Jiang Q, Xin Y, He F, Liu C, Qiu J.
europepmc +1 more source
P124 TRANSCRIPTION FACTORS SOX2 AND PDX-1 IN ULCERATIVE COLITIS AND ASSOCIATED NEOPLASIA - ARE THEY RELATED TO GASTRIC APOMUCIN EXPRESSION AND INVOLVED IN CARCINOGENESIS? [PDF]
Paula Borralho +5 more
openalex +1 more source
Abstract Objective Conditions presenting with both epilepsy and movement disorders (EPIMDs) range from relatively benign cases to severe developmental encephalopathies. However, the full clinical and genetic spectrum still needs to be better defined.
Davide Caputo +15 more
wiley +1 more source
Neurotransmitter receptor-associated gene signature: prognostic and immunosuppressive microenvironment in NSCLC. [PDF]
Yang Y +6 more
europepmc +1 more source

