Results 191 to 200 of about 66,099 (245)

Human adult hippocampal neurogenesis in health and disease. [PDF]

Aging Brain
Alonso-Moreno MC, Gallardo-Caballero M, Prádanos-Senén AV, Llorens-Martín M.   +3 more
europepmc   +1 more source

Dysregulation of Rho‐Associated Coiled‐Coil Protein Kinase1 Depletes Neural Stem Cell Pool and Impairs Hippocampal Neurogenesis After Traumatic Brain Injury

Cell Proliferation, EarlyView.
Following TBI, hippocampal neurogenesis in mice is impaired and affects cognitive function. This impairment is associated with the upregulation of p‐AKT/AKT mediated by ROCK1. ABSTRACT Traumatic brain injury (TBI) represents a global health burden, often resulting in persistent neurological deficits due to impaired hippocampal neurogenesis ...
Chaoqun Yao, Long Jin, Jun Zhong, Qianying Huang, Zhongwei Bao, Shaolong Zhou, Chaohua Wang, Huanhuan Li, Xiaowei Yuan, Zhen Wang, Ning Du, Jingxuan Yu, Huanran Chen, Xuyang Zhang, Hongfei Ge, Jianheng Wu   +15 more
wiley   +1 more source

α7 nicotinic acetylcholine receptors regulate radial glia fate in the developing human cortex. [PDF]

Nat Commun
Mukhtar T, Siebert CV, Wang Y, Pebworth MP, White ML, Wu T, Huang TI, Zuo G, Ross J, Baltazar J, Upadhyay V, Shankar M, Zhou L, Lombardi-Coronel I, Mandala I, Adam MA, Wang S, Bi Q, Hoekman MFM, Li J, Kriegstein AR.   +20 more
europepmc   +1 more source

Comparison of clinical manifestations and immunoreactivities of Meckel's diverticulum with and without gastric heteroplasia. [PDF]

Front Pediatr
Zhang TT, Zhou XG, Cai P, Zhang RY, Zhu ZW.   +4 more
europepmc   +1 more source

Evolutionary Analysis of Transcriptional Regulation Mediated by Cdx2 in Rodents

Cell Proliferation, EarlyView.
Our study (1) represented a first systematic analysis of species‐specific adaptation in the DNA binding pattern of transcription factor; (2) represented a first study of cis‐regulation between two reproductively isolated species by using a novel allodiploid system; (3) demonstrated a higher conservation of transcriptional output than that of DNA ...
Weizheng Liang, Guipeng Li, Yukai Wang, Wencheng Wei, Rui Chen, Siyue Sun, Diwen Gan, Hongyang Yi, Bernhard Schaefke, Yuhui Hu, Qi Zhou, Wei Li, Huanhuan Cui, Wei Chen   +13 more
wiley   +1 more source

Cellular senescence-related gene signatures in idiopathic pulmonary fibrosis: insights from bioinformatics. [PDF]

Front Immunol
Weng S, Zuo J, Mo J, Ye L.
europepmc   +1 more source

Sox2 expression in breast tumours and activation in breast cancer stem cells

, 2011
Olatz Leis, Arrate Eguiara, Erika López‐Arribillaga, María Jesus Alberdi, Susana Hernández-García, Kepa Elorriaga, Atanasio Pandiella, Ricardo Rezola, Ángel G. Martín   +8 more
openalex   +1 more source

Transcription Factor TCF12‐Mediated Maternal Gene Expressions in Mouse Oocyte Are Prerequisites of Successful Fertilisation and Zygotic Genome Activation

Cell Proliferation, EarlyView.
Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao, Chi Zhang, Zuo‐Qi Deng, Yue‐xin Qiu, Zhao Zhang, Heng‐Yu Fan, Jing Li, Hong‐Bo Wu   +7 more
wiley   +1 more source

All-Trans Retinoic Acid Induces Differentiation and Downregulates Stemness Markers and MGMT Expression in Glioblastoma Stem Cells. [PDF]

Cells
Tang J, Yang R.
europepmc   +1 more source

Foxg1 and Retinoic Acid Signaling Regulate Zonal Patterning in the Developing Olfactory Epithelium

Development, Growth &Differentiation, EarlyView.
ABSTRACT Odor information processing begins in the olfactory epithelium (OE), which in mice is spatially divided into two zones: the dorsomedial zone (D‐zone), responsible for innate aversive behaviors, and the ventrolateral zone (V‐zone), associated with learning‐dependent behaviors.
Anzu Kuriyama, Carina Hanashima
wiley   +1 more source