Results 221 to 230 of about 70,586 (295)

Par6/SOX2 interact to modulate stemness maintenance in glioma by regulating the EGFR/PI3K/AKT signaling cascade. [PDF]

Oncogene
Yang T, Zeng Y, Li Y, Huang Y, Meng X, Lu C, Zhu C, Liu P, Liu J, Hao S, Luo J, Cui W, Yang X.   +12 more
europepmc   +1 more source

SOX2 a master gene regulating progression in prostate cancer

, 2016
Diana Ribeiro
openalex   +1 more source

Lactate Dehydrogenase Inhibition Reverts the Fatty Acid‐Induced Neurotoxic Phenotype of Astrocytes

Glia, Volume 74, Issue 3, March 2026.
ALS models display increased LD accumulation. LD accumulation is linked to a neurotoxic phenotype in astrocytes. Lactate dehydrogenase inhibition reverts LD accumulation in ALS astrocytes. ABSTRACT Astrocytes are central to lipid metabolism in the central nervous system.
Daniel Esteve, Mariana Bresque, Daniel Okhuevbie, Sandhya Ramachandran, Mariana Pehar, Marcelo R. Vargas   +5 more
wiley   +1 more source

YTHDC2 suppresses bladder cancer by inhibiting SOX2-mediated tumor plasticity. [PDF]

Cell Death Dis
Cai Y, Zhu C, Shi MH, Zhang JH, Liu SY, Cui JL, Guo MM, Ming DJ, Zeng XT, Yuan S, Weng H.   +10 more
europepmc   +1 more source

SOX2 and cancer: current research and its implications in the clinic

, 2014
Kasia Weina, Jochen Utikal
openalex   +1 more source

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang, Bin Lu, Haotian Shang, Wanjing Ding, Chunhua Wei, Xiaotian Qi, Pengxing He   +6 more
wiley   +1 more source

Postnatal sustentacular cells as chromaffin progenitors and tumor cells of origin in VHL-related paragangliomas. [PDF]

NPJ Precis Oncol
Bullova P, Cui P, Arceo M, Zhu J, Li W, Plescher M, Poltorachenko V, Stripling K, Santangeli C, Mykhaylechko L, Kastriti ME, Larsson C, Juhlin CC, Mints M, Schlisio S.   +14 more
europepmc   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Identification, Isolation, and In Vitro Culture Trials of Ovarian Germ Stem Cells from Different Teleost Fish Species. [PDF]

Vet Sci
Varvara C, Ventriglia G, Pousis C, Di Gioia T, Zupa R, Del Frassino DM, Corriero A, Martinello T.   +7 more
europepmc   +1 more source

Engineering a Perfusion Bioreactor System for hiPSC‐Derived Progenitor Co‐Culture Capturing Microglial Features in CNS Development

Biotechnology and Bioengineering, Volume 123, Issue 2, Page 363-378, February 2026.
The authors report the development of a controlled and scalable 3D co‐culture system combining hiPSC‐derived erythromyeloid progenitors and neurospheres within the Ambr® 250 Modular platform operated with a newly designed perfusion system. This model faithfully recapitulates early microglia–neural interactions, enabling progenitor integration ...
Catarina M. Gomes, Inês de Sá, Margarida Delgado, Paula M. Alves, Catarina Brito   +4 more
wiley   +1 more source